Clinical trials: Cerebral Vascular Accident
Chronic Stroke
Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke
Stroke often impairs lower limb control, resulting in gait abnormalities and difficulties in dual-task performance, such as walking while engaging in cognitive activities.
- Trial name
- NCT06818240
- Testing
- Active transcranial direct current stimulation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Ischemic Stroke
Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on DA414
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and Food Effects of DA414 Granules in Chinese healthy subjects with single and multiple doses.
- Trial name
- DA414 (NCT06525168)
- Testing
- DA414 Granules
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Chendu DIAO Nine Hong Pharmaceutical Factory
Stroke, Myocardial Infarction
Impact of a Therapeutic Education Program of Patient on the Evolution of the Cardiovascular Chronic Disease
The Exploration Center for Prevention and Treatment of Atherosclerosis (CEPTA, Bordeaux Hospital University) showed that following myocardial infarct (MI) or ischemic stroke (TIA or stroke), the global management (medical and…
- Trial name
- ETHEPAT (NCT02819791)
- Testing
- Optimized conventional therapy alone, Optimized conventional therapy with therapeutic education
- Where
- France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Bordeaux
Stroke, Acute, Brain Edema
Automatic PredICtion of Edema After Stroke
To use machine learning for early detection of malignant brain edema in patients with MCA ischemia
- Trial name
- APICES (NCT04057690)
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,687 people
- Sponsor
- University Hospital Tuebingen
Ischemic Stroke
Stem Cell Infusion in the Treatment of Patients with Neurological Sequelae After Ischemic Stroke
This trial is to investigate the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs (UC-MSCs) in combination with standard neurological complications after ischemic stroke…
- Trial name
- NCT05292625
- Testing
- UC-MSC infusion via intravenous route, UC-MSC infusion via intrathecal route, standard stroke treatment and rehabilitation therapy
- Where
- Vietnam
- Volunteers
- 48 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Stroke
Unilateral Strength Training and Mirror Therapy for Chronic Stroke Patients
This is a pilot randomised controlled trial investigating a combination of unilateral strength training (cross-education) and mirror therapy for the rehabilitation of lower limb impairment following a stroke.
- Trial name
- NCT03497650
- Testing
- Mirror Therapy, Cross-Education of Strengthening.
- Where
- Ireland
- Volunteers
- 35 people
- Sponsor
- Institute of Technology, Sligo
Ischemic Stroke
Efficacy of Transcranial Direct Current Stimulation in Acute Ischemic Stroke
Non-invasive brain stimulation (tDCS) such as transcranial direct current stimulation (TDCS) has been reported to be effective in improving motor performance and safe in participants with cerebral infarction.
- Trial name
- DAS (NCT04938076)
- Testing
- Transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- Incheon St.Mary's Hospital
Ischemic Stroke
Clinical Trial to Assess the Efficacy and to Evaluate Safety of HT047 in Patients With Acute Ischemic Stroke
To assess the efficacy and to evaluate safety of HT047 in patients with acute ischemic stroke
- Trial name
- NCT02828540
- Testing
- HT047 High-dose group, HT047 Low-dose group
- Where
- 8 sites in South Korea
- Volunteers
- 78 people
- Sponsor
- Hocheol Kim
Stroke, Aphasia
MIT Intensive Treatment Study
This study is examining the use of intensive melodic intonation therapy and video feedback as a means of aiding individuals with nonfluent aphasia and co-occurring motor speech impairments.
- Conditions
- Stroke, Aphasia, Motor Speech
- Trial name
- MITTXS (NCT06213376)
- Testing
- Melodic Intonation Therapy, Video Feedback Performance Review
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Nevada State University
Stroke, Hemiplegia
Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation
The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical stimulation (EES) of the spinal…
- Trial name
- Stroke-BSI (NCT07610850)
- Testing
- ARC-BSI Stroke system
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Hemianopsia
tDCS Associated to Blindsight Rehabilitation for the Treatment of Homonymous Hemianopsia
Homonymous hemianopia is one of the most common symptoms following a neurologic damage and has many negative effects on functional abilities and daily activities.
- Trial name
- TABRTHH (NCT02956668)
- Testing
- Blindsight Training associated to tDCS, Blindsight Training alone
- Where
- Italy
- Sponsor
- University of Milano Bicocca
Hemiparetic Stroke
Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments
Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over the past two decades.
- Trial name
- NCT07599774
- Testing
- High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Carle Foundation Hospital
Intracerebral Hemorrhage
Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial
Rationale: Management of blood pressure (BP) in the acute phase of intracerebral hemorrhage (ICH) remains controversial. Although it has been established that there is a transient moderate reduction of perihematoma cerebral blood…
- Trial name
- ICH ADAPT (NCT00963976)
- Testing
- labetalol/hydralazine/enalapril
- Where
- 4 sites in Canada
- Volunteers
- 74 people
- Sponsor
- University of Alberta
Aneurysmal Subarachnoid Hemorrhage
Decompressive Craniectomy After Aneurysmal Subarachnoid Hemorrhage (DECIDE-SAH)
DECIDE-SAH is an international, multicenter, retrospective, observational, non-interventional secondary-use cohort study of adults with aneurysmal subarachnoid hemorrhage (aSAH).
- Trial name
- DECIDE-SAH (NCT07872774)
- Testing
- Decompressive craniectomy
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Essen
Ischemic Stroke, Acute, Tumor Progression
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of AIS With Active Cancer
Explore with active cancer patients with acute ischemic stroke in the human body characteristic microorganism disorder to clinical prognosis of the predictive value of the secondary objective: to observe with active cancer…
- Trial name
- NCT05553990
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke, Atrial Fibrillation
Stroke Lesion Pattern on MRI and Atrial Fibrillation
The aim of this retrospective cohort study is to investigate the relationship between lesion pattern on Magnetic Resonance Imaging (MRI) and atrial fibrillation in patients with acute ischemic stroke.
- Trial name
- SLPAF (NCT02606890)
- Testing
- MRI
- Volunteers
- 1,000 people
- Sponsor
- Charite University, Berlin, Germany
Ischemic Stroke
Mild and Rapidly Improving Stroke Study
The objective of this study is to determine the 90-day outcomes of mild and rapidly improving ischemic stroke.
- Trial name
- MaRISS (NCT02072681)
- Where
- 97 sites in United States
- Volunteers
- 2,175 people
- Sponsor
- University of Miami
Stroke
Locomotor Experience Applied Post Stroke Trial
The purpose of this study is to compare two different treatments to improve walking after stroke (or post-stroke).
- Trial name
- LEAPS (NCT00243919)
- Testing
- Early locomotor training program, Late locomotor training program, Home Exercise Program
- Where
- 8 sites in United States
- Volunteers
- 408 people
- Sponsor
- Duke University
Heart Disease Risk Factors
mHealth-supported Coach
A randomised controlled trial to evaluate the effects of a personalised mHealth-supported coach programme in the middle-aged group with stroke risk.
- Trial name
- NCT05422729
- Testing
- mHealth-supported coaching, Conventional Health coaching
- Where
- Hong Kong
- Volunteers
- 164 people
- Sponsor
- Food and Health Bureau, Hong Kong
Cerebral Infarction
Glycemia and Ischemia Reperfusion Brain Injury in Patients With Acute Cerebral Infarction Treated With Mechanical Thrombectomy
Postictus hyperglycemia is associated with an accelerated transformation of the ischemic penumbra into an infarct area, with increased infarct size, worse recanalization, reduced cerebral perfusion, increased ischemia reperfusion…
- Trial name
- NCT05871502
- Testing
- Subcutaneous blood glucose monitoring device
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
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