Clinical trials: Cerebral Vascular Accident
Acute Ischemic Stroke
MRI-based Artificial Intelligence Software (NNS-SOT) for Onset Time Estimation in Lesion With Acute Ischemic Stroke
This study evaluates the efficacy of investigational device named Stroke Onset Time Artificial Intelligence(AI) (Model name:NNS-SOT).
- Trial name
- NCT06160726
- Where
- South Korea
- Volunteers
- 474 people
- Sponsor
- Nunaps Inc
Stroke
Rehabilitation of the Stroke Hand at Home
The purpose of this research is to evaluate a therapy delivery system for stroke patients that provide accessible, affordable stroke care.
- Trial name
- HAAPI (NCT01144715)
- Testing
- Hand Mentor (TM) robotic stroke therapy device, Home Therapy Program
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Kinetic Muscles
Tbi, Vasospasm
Cerebral Autoregulation and Vasospasm in Patients With TBI
Traumatic brain injury (TBI) affects 1.5 million patients per year in the United States, resulting in more than 50,000 deaths and more than 230,000 hospitalizations annually.
- Conditions
- Tbi, Vasospasm, Cerebral Ischemia, Cerebral Infarct
- Trial name
- NCT02351518
- Testing
- No intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cardiac Output, Decreased Cardiac Output
Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients
The objective of this study is to investigate the hemodynamic effects of two strategies of alveolar recruitment maneuver in patients undergoing major abdominal surgery in the operating room
- Conditions
- Cardiac Output, Decreased Cardiac Output, Hemodynamic Monitoring, Blood Pressure
- Trial name
- CHARM-Bloc (NCT05365113)
- Testing
- alveolar recruitment maneuver
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Stroke, Chronic Stroke Patients
RESPARK - Brain Q for Chronic Stroke
This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers non-invasive…
- Conditions
- Stroke, Chronic Stroke Patients, Cerebrovascular Accident (CVA)
- Trial name
- NCT07095920
- Testing
- Device: Q Therapeutic System (BQ 3.0) - Active
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Ischemic Stroke
Stroke and Tocotrienol: Unique Role in Neuroprotection
Phase III, single-centre, double-blind, randomised, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of oral Vitamin E (Mixed Tocotrienol) for 6 months in patients with moderate ischemic stroke.
- Trial name
- SATURN (NCT02263924)
- Testing
- Tocotrienol
- Where
- Malaysia
- Volunteers
- 150 people
- Sponsor
- Seberang Jaya Clinical Research Centre
Stroke
The Prehospital Selection of Acute Stroke Patients
The aim of this study is to develop and validate a simple prehospital stroke scale, which would predict the presence of large vessel occlusion (LVO) in patients with acute stroke.
- Trial name
- NCT03072524
- Testing
- FAST PLUS test
- Where
- 4 sites in Czechia
- Volunteers
- 400 people
- Sponsor
- University Hospital Ostrava
Lacunar Strokes
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts
The aim of this study is to determine in patients with a recent lacunar strokes (<15 days), the natural history of cognitive disturbances and disability.
- Trial name
- DHU-LAC (NCT03552926)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Pulmonary Ventilation
Ventilatory Muscle Training in Stroke
The purpose of the present study is to determine the utility and effectiveness of combined inspiratory (IMT) and expiratory muscle training (EMT) in improving ventilatory function in people who are disabled by long-term stroke…
- Conditions
- Stroke, Pulmonary Ventilation, Exercise Therapy
- Trial name
- NCT02828943
- Testing
- IMT with High Resistance EMT, IMT with Low Resistance EMT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
DIROXIMEL FUMARATE TO REDUCE PERIHAEMATOMAL OEDEMA IN INTRACEREBRAL HAEMORRHAGE: DOUBLE BLIND RANDOMIZED CLINICAL TRIAL
Spontaneous intracerebral haemorrhage (ICH) is a life-threatening condition, still devoided of specific treatment. Peri-haematomal oedema (PHO) develops in the ensuing days after ICH onset and worsens functional outcome.
- Trial name
- DARLENE (NCT07275515)
- Testing
- DRF
- Where
- France
- Volunteers
- 192 people
- Sponsor
- University Hospital, Lille
Acute Ischemic Stroke
Study on the Effectiveness and Safety of Nitrone for Injection in Patients With Acute Ischemic Stroke
The main purpose of the study: To evaluate the effect of nitrosone 1 special for patients with acute ischemic cerebral stroke. The secondary purpose of the study: To evaluate the effectiveness of the injection of nitrosone I.
- Trial name
- NCT04951440
- Testing
- Nitrate ketone oxazine
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Stroke
Feasibility Study of Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program Among People With Stroke in Bang
Stroke causes major disability issues in Bangladesh and often leaves people unable to look after themselves, work, or participate in family and community life.
- Trial name
- NCT07272759
- Testing
- Occupation-Based 'Remediation, Education, Adaptation, Promotion' (REAP) Program
- Where
- Bangladesh
- Volunteers
- 6 people
- Sponsor
- Tokyo Metropolitan University
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Anticoagulation, Atrial Fibrillation
AntiCoagulation Tracking InterVention and Evaluation
Anticoagulants are a leading cause of acute injury from adverse drug events, leading to ~20,000 serious injuries reported to the Food and Drug Administration per year and more than 220,000 emergency department visits annually.
- Conditions
- Anticoagulation, Atrial Fibrillation, Atrial Flutter, Pulmonary Embolus/Emboli
- Trial name
- ACTIVE (NCT04059965)
- Testing
- Panel Management for Anticoagulation Therapy, Usual Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke, Caregiver Social Support
Optimizing Stroke Family Caregiver Support Across the Care Continuum by Improving the Timing of Intervention Delivery
About 50% of stroke survivors have limitations in their activities of daily living on return to the community. Family caregivers provide invaluable support to these individuals during their recovery and rehabilitation.
- Conditions
- Stroke, Caregiver Social Support, Caregiver Mental Health, Caregiver Sense of Control Over Life
- Trial name
- NCT00958607
- Testing
- Timing it Right Stroke Family Support Person Intervention, Self-directed program
- Where
- Canada
- Volunteers
- 310 people
- Sponsor
- University of Toronto
Post Stroke Delirium
Melatonin for Prevention of Post Stroke Delirium
Post stroke delirium is prevalent in 10-30% of all stroke patients. We aimed to investigate wether Melatonin 2mg may prevent post stroke delirium.
- Trial name
- NCT04122599
- Testing
- Melatonin
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Tuebingen
Cerebral Infarction, Brain Ischemia
Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke
Based on previous studies comparing Duteplase[a recombinant tissue plasminogen activator (rt-PA) very similar to alteplase] doses, we performed a clinical trial with 0.6mg/kg, which is lower than the internationally approved…
- Trial name
- NCT00147316
- Testing
- Alteplase
- Where
- Japan
- Volunteers
- 103 people
- Sponsor
- Tanabe Pharma Corporation
Upper Extremity Paresis, Stroke, Chronic
Non-invasive Trigeminal and Vagus Nerve Stimulation for Stroke Subjects With Chronic Upper Extremity Deficits
This is a single-center, multiphase pilot study of 16 subjects with residual upper extremity deficits at least six months after a supratentorial ischemic or hemorrhagic stroke.
- Trial name
- NCT06288217
- Testing
- NeuraStasis Stimulator System (Non-Invasive Trigeminal and Vagus Nerve Stimulation), Upper Limb Rehabilitation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NeuraStasis, Inc
Stroke
Real-time Neuromuscular Control of Exoskeletons
The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature.
- Trial name
- NCT04661891
- Testing
- Isometric contractions, Isokinetic contractions, Dynamic contractions
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence.
- Trial name
- CN-NINM (NCT06386510)
- Testing
- Strength training, Cranial nerve non-invasive neuromodulation
- Where
- 3 sites in Canada
- Volunteers
- 74 people
- Sponsor
- Université de Sherbrooke
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