Clinical trials: Cerebral Vascular Disorder
Stroke
Transitional Care Model for Patients With Stroke
Patients with stroke benefitted from superior improvements in physical function, particularly when performing activities of daily living, fewer visits to the emergency room, less depression symptoms, and improved health-related…
- Trial name
- NCT06280599
- Testing
- Transitional care model
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Kaohsiung Medical University
Stroke, Ischemic
Comparison of Robot Assisted Gait Training and Body Weight Supported Treadmill Training Using Gait Analysis and SEMG Measurements
The aim of our randomized controlled clinical trial was to analyze the effects of robotic-assisted gait training and body-weight-supported treadmill training on gait analysis parameters and lower extremity agonist and antagonist…
- Trial name
- NCT06715098
- Testing
- RoboGait, RehaWalk, Conventional
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Pamukkale University
Kinesiophobia, Stroke
Examining the Relationship Between the Presence of Kinesiophobia in Stroke Patients and Balance, Gait, Pain, and Social Participation Levels
The aim of this study is to detect the presence of kinesiophobia, which may affect treatment in stroke patients, and to have an idea about its relationship with kinesiophobia by examining factors such as balance, gait, pain and…
- Trial name
- NCT06202287
- Testing
- Balance measurements using the HUR Smart balance device, balance tests, and other surveys.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Motor Dysfunction
Closed-Loop SCS-BCI for Post-Stroke Hemiplegia
This study evaluates a new closed-loop rehabilitation system for stroke survivors with arm weakness. The system combines a brain-computer interface (BCI, a special cap that reads brain signals), spinal cord stimulation (a…
- Conditions
- Stroke, Motor Dysfunction, Brain-computer Interface, Spinal Cord Stimulation (SCS)
- Trial name
- CL-SCS-BCI (NCT07903116)
- Testing
- Spinal Cord Stimulation, Non-invasive Brain-Computer Interface, Hand Exoskeleton
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute
Treatment Evaluation of Acute Stroke for Using in Regenerative Cell Elements
The primary objectives of this study is to evaluate the efficacy of HLCM051 on functional outcome in subjects with acute ischemic stroke and to evaluate the safety of HLCM051 in subjects with acute ischemic stroke.
- Trial name
- TREASURE (NCT02961504)
- Testing
- HLCM051
- Where
- Japan
- Volunteers
- 206 people
- Sponsor
- Healios K.K.
Stroke
The Application of Thermal Stimulation on Functional Recovery of Stroke Patients
In literature review, thermal stimulation (TS) intervention is effective in facilitating upper extremity functional recovery in stroke patients.
- Trial name
- NCT01418404
- Testing
- Noxious TS, Innocuous TS, High Frequency of Noxious TS
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Mitochondrial Diseases
EPI-743 for Mitochondrial Respiratory Chain Diseases
This study will evaluate the safety and efficacy of EPI-743 in participants with severe mitochondrial respiratory chain diseases who are considered to be within 90 days of end-of-life care.
- Trial name
- NCT01370447
- Testing
- EPI-743
- Where
- 16 sites in United States
- Sponsor
- PTC Therapeutics
Ischemic Stroke
Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 300 mg clopidogrel were assessed…
- Trial name
- NCT06591338
- Testing
- Ticagrelor 90 MG, Clopidogrel, Aspirin 75 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Ischemic Cerebrovascular Accident
Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke
This study is to test a hypothesis that temporary implantation of JRecanTM blood flow recanalisation device within 6.5 hours of symptom onset of acute ischemic stroke due to a major intracranial artery occlusion following IV…
- Trial name
- NCT02347358
- Testing
- JRecanTM blood FR device, IV r-tPA
- Volunteers
- 100 people
- Sponsor
- The Second Artillery General Hospital
Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
Screening Patients With Fabry Disease in Patients With Hypertrophic Cardiomyopathy or Left Ventricular Hypertrophy
The purpose of this study was to understand the epidemiological status of Fabry in patients with hypertrophic cardiomyopathy or left ventricular hypertrophy through multi-center early identification of high-risk patients in…
- Conditions
- Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy, Fabry Disease
- Trial name
- SEARCH (NCT06169358)
- Where
- China
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Pulmonary Hypertension
Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease
To evaluate the acute effect of recombinant human brain natriuretic peptide(rhBNP) on pulmonary hypertension of acute exacerbations of chronic pulmonary disease.
- Trial name
- NCT02742909
- Testing
- rhBNP
- Where
- China
- Volunteers
- 9 people
- Sponsor
- LI ZHAO
Stroke, Hemineglect
Effect of Immersive Virtual Reality With Multisensory Stimulation on the Functional Impact of Hemineglect Secondary to a Right-Sided Stroke
A stroke is a common and potentially serious condition that affects 130,000 people each year in France. It is the second leading cause of major cognitive disorders after Alzheimer's disease.
- Conditions
- Stroke, Hemineglect, Neuropsychology, Virtual Reality
- Trial name
- NEGLISENS (NCT06719063)
- Testing
- Multisensory Virtual Reality
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hopital La Musse
Stroke, Acute
Bed Bridge Test in Acute Stroke Patients
Studies examining the validity and reliability of easy-to-apply muscle strength and mobility outcome measures in the acute and subacute phases of stroke are quite limited.
- Trial name
- NCT07155538
- Testing
- Assesment test for Validity and Reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gaziantep Islam Science and Technology University
Ischemic Stroke, Ischemia
Biomarkers of Acute Stroke in Clinic
The proposed study will investigate the clinical use of the ISCDX test that may differentiate between diverse stroke etiologies as listed below: Aim 1: Differentiate between cardioembolic and large artery atherosclerotic ischemic…
- Conditions
- Ischemic Stroke, Ischemia, Atrial Fibrillation, Transient Ischemic Attack
- Trial name
- BASIC (NCT03897478)
- Testing
- ISCDX blood test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ischemia Care LLC
Cerebrovascular Accident
Safety and Efficacy of Autologous Stem Cell Therapy in Chronic Stroke
The purpose of this study was to study the safety and effect of stem cell therapy on the functional recovery in patients with chronic stroke.
- Trial name
- NCT02065778
- Testing
- Autologous bone marrow mononuclear cell transplantation
- Where
- India
- Sponsor
- Neurogen Brain and Spine Institute
Primary Hypertension
China Stroke Primary Prevention Trial
The purpose of this trial is to confirm that enalapril maleate and folic acid tablets is more effective in preventing stroke among the patients with primary hypertension when compared to enalapril maleate.
- Trial name
- CSPPT (NCT00794885)
- Testing
- Enalapril/folic acid, Enalapril maleate
- Where
- 2 sites in China
- Volunteers
- 20,702 people
- Sponsor
- Shenzhen Ausa Pharmed Co.,Ltd
Ischemic Heart Disease, Transient Ischemic Attack
TomVasc - Vascular Effects of Tomato Extract
Does tomato extract improve blood vessel function in healthy people and people with cardiovascular disease? Atherosclerosis ('furring' of the arteries) affects the functioning of blood vessels, narrowing and eventually blocking…
- Conditions
- Ischemic Heart Disease, Transient Ischemic Attack, Stroke, Peripheral Vascular Disease
- Trial name
- TomVasc (NCT01100385)
- Testing
- Ateronon
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Acute Stroke, Paresis
Study of Robot-assisted Arm Therapy for Acute Stroke Patients
The purpose of this study is to compare standard occupational therapy to a combination of conventional (standard) and robotic therapy.
- Trial name
- NCT00785343
- Testing
- Reo Go robotic arm trainer, Conventional Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Acute Ischemic Stroke
Safety of DS-1040b in Acute Ischemic Stroke Patients Treated With Thrombectomy
The aim of this study is to find out if DS-1040b is safe and tolerable in acute ischemic stroke patients with thrombectomy. Four groups will receive different doses of DS-1040b by intravenous infusion for 6 hours.
- Trial name
- NCT03198715
- Testing
- DS1040b
- Where
- 20 sites in Japan
- Volunteers
- 42 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Stroke
Assistive Soft Robotic Glove Intervention Using Brain-Computer Interface for Elderly Stroke Patients
This research aims to integrate and develop a novel Brain-Computer Interface (BCI) controlled soft robotic glove, evaluate the ability of the glove in achieving common hand grasping postures and to assess the efficacy of the…
- Trial name
- NCT03277508
- Testing
- BCI Robot Assisted Hand Therapy, CPM Robot Assisted Hand Therapy
- Where
- Singapore
- Volunteers
- 11 people
- Sponsor
- National University Hospital, Singapore