Clinical trials: Cerebral Venous Sinus Thrombosis
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Sinus Thrombosis, Intracranial
Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
Background: Endovascular thrombolysis, with or without mechanical clot removal (ET), may be beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT), who have a poor prognosis despite treatment with…
- Trial name
- TOACT (NCT01204333)
- Testing
- Endovascular thrombolysis, Heparin
- Where
- 15 sites in Canada, China and 4 more
- Volunteers
- 67 people
- Sponsor
- Jan Stam, MD, PhD
Cerebral Venous Sinus Thrombosis
MENA Regional Endovascular Intervention for Venous Cerebral Venous Sinus Thrombosis
REVIVE-CVST is a multicenter, prospective, randomized, open-label, blinded-endpoint (PROBE) trial evaluating whether early endovascular thrombectomy (EVT) combined with standard anticoagulation improves outcomes compared to…
- Trial name
- REVIVE-CVST (NCT07548346)
- Testing
- Endovascular Thrombectomy, Anticoagulation Therapy
- Where
- 14 sites in Egypt, Jordan and 6 more
- Volunteers
- 440 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Cerebral Venous Sinus Thrombosis
Endovascular Treatment or Standard Medical Care for Cerebral Venous Sinus Thrombosis(ESCORT)
Background: It has not been extensively studied in differing populations that endovascular treatment (EVT) for acute and subacute CVST with multimodal imaging selection improves the functional outcome better than standard medical…
- Trial name
- ESCORT (NCT06583889)
- Testing
- Heparin, Endovascular treatment
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Venous Sinus Thrombosis
The Dedicated Venous Sinus Thrombectomy Stent for Endovascular Treatment of Cerebral Venous Sinus Thrombosis.
A prospective, single-center, open-label,randomized, controlled,non-inferiority clinical trial will be conducted to evaluate the safety and efficacy of a dedicated venous sinus thrombectomy stent for endovascular treatment of…
- Trial name
- NCT05291585
- Testing
- the dedicated venous sinus thrombectomy stent, balloon catheter thrombectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ji Xunming,MD,PhD
Stroke, Superior Sagittal Sinus Thrombosis
Comparison of the Radiological Pattern Between the Cerebral Stroke of Arterial and Venous Origin
There are few published data on the patterns of parenchymal imaging abnormalities in a context of cerebral venous thrombosis (CVT).
- Conditions
- Stroke, Superior Sagittal Sinus Thrombosis, Venous Thromboses
- Trial name
- PATTERN (NCT03611894)
- Testing
- radiological comparison
- Where
- 2 sites in France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Intracranial Thrombosis
Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates
Our overall aim is to examine if ultrasound is as accurate as MRI and/or CT in the evaluation of dural venous sinuses. We hypothesize that sonography will be accurate (accuracy >80%) for diagnosing specific anatomic findings of…
- Trial name
- NCT00555932
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- The Hospital for Sick Children
Cerebral Venous Sinus Thrombosis, CSF Pressure Increased
Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales
This is a single-center, retrospective, open-label study. This study is planned to investigate the accuracy of mRS and NIHSS, comparing with the accuracy of CSF pressure and papilledema grade in assessing cerebral venous sinus…
- Conditions
- Cerebral Venous Sinus Thrombosis, CSF Pressure Increased, Papilledema
- Trial name
- NCT03273179
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Thromboembolism
A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT)
This is a multi-center, prospective, international, randomized (1:1), open-label study with two parallel groups. This phase III study is planned to investigate the efficacy and safety of dabigatran etexilate versus dose-adjusted…
- Trial name
- NCT02913326
- Testing
- Dabigatran etexilate, Warfarin
- Where
- 36 sites in France, Germany and 7 more
- Volunteers
- 120 people
- Sponsor
- Boehringer Ingelheim
Stroke, Acute Stroke
Stroke and Cerebrovascular Diseases Registry
This is a single institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the fifth leading cause of death in the United States.
- Conditions
- Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke
- Trial name
- NCT03281590
- Where
- United States
- Volunteers
- 4,594 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cerebral Vein Thrombosis
Venous Sinus Thrombosis : Clinical Picture and Outcome
Cerebral venous sinus thrombosis (cvst) is an underdiagnosed neurological condition with variable clinical presentations and variable risk factors CVST is often an underdiagnosed cause of acute or slowly progressive neurological…
- Trial name
- NCT05211102
- Volunteers
- 50 people
- Sponsor
- Assiut University
Cerebral Vein Thrombosis, Cerebral Venous Sinus Thrombosis
Multicenter Registry Study Of Cerebral Venous Thrombosis In China (RETAIN-CH)
This study will investigate the epidemiology, risk factors, diagnostics, treatment, and the long-term prognosis of cerebral venous thrombosis in China.
- Trial name
- NCT05448248
- Where
- China
- Volunteers
- 3,276 people
- Sponsor
- Capital Medical University
Cerebral Venous Sinus Thrombosis
Dabigatran Versus Rivaroxaban in Cerebral Venous Thrombosis
Along with the current clinical trial, the efficacy and safety of a 150 mg Bid dabigatran administered within 24 hours of randomization after having first-ever cerebral venous thrombosis compared to 20 mg rivaroxaban were…
- Trial name
- NCT06551402
- Testing
- Dabigatran Etexilate 150mg, Rivaroxaban 20 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Cerebral Venous Sinus Thrombosis
Dabigatran Versus Apixaban in Cerebral Venous Thrombosis
Along with the current clinical trial, the efficacy and safety of a 150 mg Bid dabigatran administered within 24 hours of randomization after having first-ever cerebral venous thrombosis compared to apixaban 5mg Bid were assessed…
- Trial name
- NCT06551415
- Testing
- Dabigatran Etexilate 150mg, Apixaban 5MG
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Venous Sinus Thrombosis, Cranial
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding…
- Trial name
- NCT05413837
- Testing
- anotomy and variation of venous sinus, the level of biomarker in bood
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Cerebral Venous Sinus Thrombosis
Glymphatic Function and White Matter Integrity in Cerebral Venous Disorders
Cerebral venous disorders, including cerebral venous sinus stenosis (CVSS) and cerebral venous sinus thrombosis (CVST), can obstruct venous blood drainage, leading to intracranial hypertension.
- Trial name
- NCT07072663
- Testing
- Baseline and 3-month follow-up, Baseline
- Where
- China
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Venous Thromboembolism
Thrombosis Outcomes in Pediatric Venous Thromboembolism
'The TOP Study' is a prospective cohort study whose main objective is to develop better prognostic biomarkers and identify children at risk of adverse thrombotic outcomes very early in the course after an initial venous…
- Trial name
- TOP (NCT03068923)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Texas Southwestern Medical Center
Cerebral Vein Thrombosis, Cerebral Venous Sinus Thrombosis
The Norwegian Cerebral Venous Thrombosis Study
The NoCVT study will investigate CVT (2014-2023) in a large Norwegian population (> 3 millions) using several approaches combining existing health registries, clinical databases and new prospectively collected clinical data to…
- Trial name
- NoCVT (NCT05021198)
- Where
- Norway
- Volunteers
- 600 people
- Sponsor
- University Hospital, Akershus
Lateral Sinus Thrombosis, Mastoiditis
Otogenic CSVT Retrospective Case Series and Associated Thrombophilia
The aim of this study is to report the clinical presentation, Microbiological, laboratory and imaging evaluation, prothrombotic factors analysis, medical and surgical management and outcomes in children with Otogenic Cerebral…
- Conditions
- Lateral Sinus Thrombosis, Mastoiditis, Otitis Media
- Trial name
- CSVT PCR (NCT03864055)
- Where
- Israel
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel