Clinical trials: Cerebrovascular Apoplexy
Coma, Traumatic Brain Injury
Continuous Quantified EEG in NeuroIntensive Care
To evaluate the ability of NICU (NeuroIntensive Care Unit) staff to interpret, before and after a training period, symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG (continuous…
- Conditions
- Coma, Traumatic Brain Injury, Subarachnoid Hemorrhage, Ischemic Stroke
- Trial name
- CrazyEEG (NCT02901262)
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Multiple Sclerosis, Stroke
Short Arm Human Centrifuge Therapeutic Training and Rehabilitation (GRACER1)
The study is a single blind randomized controlled trial (RCT) designed to examine the benefit of a short arm human centrifuge intervention program (SAHC) combined with exercise, compared to a standard of care (SOC) rehabilitation…
- Conditions
- Multiple Sclerosis, Stroke, Pulmonary Disease, Chronic Obstructive, Aged
- Trial name
- GRACER1 (NCT04369976)
- Testing
- ARTIFICIAL GRAVITY COMBINED WITH EXERCISE
- Where
- Greece
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Greek Aerospace Medical Association and Space Research
Stroke
Cervical Proprioceptive Neuromuscular Facilitation and Stabilization Exercises in Stroke Patients
Randomization order tracking will be done with sequentially numbered containers. Patients participating in the study will be blinded as to which treatment group they will be included in.
- Trial name
- NCT06237140
- Testing
- PNF+ biofeedback exercise group
- Where
- Turkey (Türkiye)
- Sponsor
- Suleyman Demirel University
Ischemic Stroke, Hypercholesteremia
Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis
This study will be conducted at six medical institutions in Taiwan, recruiting patients who visit neurology outpatient clinics or are hospitalized within 30 days after an ischemic stroke.
- Trial name
- NCT07307989
- Testing
- statin + ezetimibe, Statin monotherapy (rosuvastatin or atorvastatin)
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Cerebral Venous System
Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy
The VAST study is a single-center prospective observational study that enrolled individuals with acute ischemic stroke (AIS) within 24 hours onset.
- Conditions
- Stroke, Cerebral Venous System, Reperfusion Injury
- Trial name
- VAST (NCT03838289)
- Testing
- multimodal magnetic resonance imaging or computed tomography
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Non-invasive Brain Stimulation (NIBS) and Dual-task Walking After Stroke
The study aims to identify neural locus critical for dual-task walking (walking and talking) in individuals with stroke. To achieve this aim, the investigators apply repetitive transcranial magnetic stimulation (rTMS) to…
- Trial name
- NCT03442868
- Testing
- high frequency rTMS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Texas Woman's University
Stroke, Muscle Tone Abnormalities
Stroke and Assessment of Muscle Tone
Spasticity is defined as a state of increased muscle tone, which evokes an increased resistance to a passive and fast stretching of the muscle.
- Conditions
- Stroke, Muscle Tone Abnormalities, Pain, Muscle Spasticity
- Trial name
- NCT03814460
- Testing
- Assessment of Tone, Pain and Thickness
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Seville
Ischemic Cerebrovascular Accident
Stepwise Screening for Silent Atrial Fibrillation After Stroke
The main hypothesis of this work is that an approach combining clinical parameters and biomarker assays could improve the understanding and prediction of the occurrence of silent atrial fibrillation (AF) in the acute phase after…
- Trial name
- SAFAS (NCT03570060)
- Testing
- Blood sample, Long term ECG monitor, Monitoring ECG
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Stroke, Ischemic, Quadrantanopia
Vision Loss Impact on Navigation in Virtual Reality
The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving.
- Conditions
- Stroke, Ischemic, Quadrantanopia, Hemianopsia, Homonymous, Hemianopia, Homonymous
- Trial name
- NCT06047717
- Testing
- Virtual Reality Driving Task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Stroke, Carotid Stenosis
PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis
Ischaemic stroke is a major cause of death and disability worldwide. In patients with recent stroke, the 18F-fluoride positron emission tomography-computed tomography highlights high-risk culprit carotid plaque and is more…
- Trial name
- NCT03215550
- Testing
- CEA, 18F PET-MRI, Transcranial Doppler
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Stroke, Hemiparesis
Efficacy Basics of Bihemispheric Motorcortex Stimulation After Stroke
The aim of the study is to investigate whether the combination of bihemispheric ("dual") transcranial direct current stimulation (tDCS) and motor training on 5 consecutive days facilitates motor recovery in chronic stroke.
- Trial name
- NCT01969097
- Testing
- tDCS, Motor training
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Symptomatic Chronic Middle Cerebral Artery Occlusion, Infarction, Middle Cerebral Artery
Extracranial-intracranial Bypass Surgery for Symptomatic Chronic Middle Cerebral Artery Occlusion: the CMOSS-2 Trial
The CMOSS-2 trial is a government-funded, prospective, multicenter, randomized controlled trial. It will recruit symptomatic chronic occlusion of the middle cerebral artery in patients with severe hemodynamic insufficiency.
- Trial name
- NCT05899582
- Testing
- Extracranial-Intracranial Bypass Surgery, Medical treatment alone
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Xuanwu Hospital, Beijing
Blood Disease, Cerebrovascular Accident
Stroke Prevention in Sickle Cell Anemia (STOP 2)
To determine how long blood transfusions are needed for primary stroke prevention. Also, to determine the duration of risk associated with abnormal transcranial Doppler ultrasound (TCD) and to determine the specificity of the…
- Conditions
- Blood Disease, Cerebrovascular Accident, Anemia, Sickle Cell
- Trial name
- NCT00006182
- Testing
- Blood Transfusion
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ischemic Stroke, Occlusion, Cerebrovascular
Revive AIS Patients ImmeDiately
This is a multicenter, prospective registry clinical study to evaluate the real-world efficacy and safety of intra-arterial treatment for acute ischemic stroke using Revive SE device on the basis of standardised medical treatment.
- Trial name
- RAPID (NCT03007082)
- Testing
- Revive SE intracranial thrombectomy device
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changhai Hospital
Stroke, Cerebral Infarction
Platelet Hyperreactivity to Aspirin and Stroke
STUDY QUESTIONS What is the real prevalence of platelet "resistance" to aspirin during the acute phase of stroke and after 3 months, and 1 year, as measured using different platelet function tests? Do all methods measure similar…
- Conditions
- Stroke, Cerebral Infarction, Cardiovascular Diseases, Vascular Diseases
- Trial name
- PLARAS (NCT00766896)
- Testing
- Aspirin (platelet sensitive versus platelet hyperreactivity)
- Where
- Brazil
- Volunteers
- 203 people
- Sponsor
- University of Sao Paulo
Stroke
Post-stroke Nurse-led Rehabilitation to Improve Functional Activity and Community Participation in Bangladesh
Stroke causes various levels of disability which decreases physical function for a prolonged period. The purpose of this study is to evaluate the effectiveness of a nurse-led rehabilitation program including a multidisciplinary…
- Trial name
- NCT07384650
- Testing
- in daily routine practice
- Where
- Bangladesh
- Volunteers
- 166 people
- Sponsor
- Hiroshima University
Hemiparesis as Late Effect of Cerebrovascular Disease
Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
This is a single-blinded randomized control trial aiming to explore the use of immersive virtual reality (VR) training in conjunction with real-life tasks therapy in 75 first time stroke patients with upper limb weakness.
- Trial name
- NCT04360460
- Testing
- Immersive virtual reality + related functional translation into real-life, Immersive virtual reality + non-related translation into real-life
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Loma Linda University
Stroke, Brain Injuries, Traumatic
Gait Training Through a Novel Over-ground Wearable Robotic System in People With Pyramidal Hemisyndromes
Over-ground exoskeletons for gait rehabilitation are studied enough in people suffering spinal cord injury, and its clinical use is escalating in the industrialized countries.
- Conditions
- Stroke, Brain Injuries, Traumatic, Brain Tumor Benign
- Trial name
- GAITGO (NCT04559724)
- Testing
- Indego Therapy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke, Telerehabilitation
Effects of Maximum Versus Minimum Supervised Telerehabilitation on Upper Limb Function in Post Stroke Patients
This single-blinded randomized controlled trial aims to compare the effectiveness of maximum versus minimum therapist supervision during home-based telerehabilitation for improving upper limb motor function, task performance…
- Conditions
- Stroke, Telerehabilitation, Upper Limb
- Trial name
- NCT07803003
- Testing
- Maximum supervision telerehabilitation, Minimum Supervision Telerehabilitation
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Stroke
Constraint Induced Movement Therapy for Walking in Individuals Post Stroke
To compare the effect of constraint induced movement therapy (CIMT) vs. treadmill training only on walking function in individuals post-stroke, a 6 week, single-blind, randomized training study will be conducted with three…
- Trial name
- NCT03264261
- Testing
- robotic training, treadmill training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shirley Ryan AbilityLab
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