Clinical trials: Cerebrovascular Apoplexy
Stroke
Effects of CHRIST on Upper Limb Function in Children With Pediatric Stroke
Pediatric stroke poses significant challenges due to its impact on a child's developing brain. Both ischemic and hemorrhagic strokes in children can result in long-term motor, sensory, and cognitive impairments, particularly…
- Trial name
- NCT07441057
- Testing
- CHRIST
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Stroke, Atrial Fibrillation
Prolonged Cardiac ECG Patch Versus Conventional Holter For Detecting Atrial Fibrillation After Cerebral Ischemic Event
The aim of this study is to compare the diagnostic yield of water-resistant, wireless 7-day cardiac ECG patch versus conventional 24-hour Holter recording in detecting paroxysmal atrial fibrillation in patients admitted with…
- Trial name
- PROVE-AF (NCT05082467)
- Where
- Malaysia
- Volunteers
- 320 people
- Sponsor
- Sarawak General Hospital
Ischemic Stroke
The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the…
- Trial name
- NCT03948399
- Testing
- Duplex scanning of carotid arteries, ABI measurement
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Subacute Stroke, Balance Deficits
Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients
This study examines how Inspiratory Muscle Training (IMT) combined with the Abdominal Drawing-In Maneuver (ADIM) affects balance, gait, and breathing in stroke patients.
- Trial name
- NCT06838871
- Testing
- Inspiratory Muscle Training (IMT) with Abdominal Drawing-In Maneuver (ADIM) training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Sahmyook University
Acute Ischemic Stroke
Mildronate for Acute Ischemic Stroke
Mildronate an inhibitor of carnitine-dependent metabolism, is considered an anti-ischemic drug. This study aims to evaluate the efficacy and safety of mildronate injection in treating acute ischemic stroke.
- Trial name
- NCT01831011
- Testing
- mildronate injection, cinepazide maleate injection, aspirin
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Xijing Hospital
Stroke, Hypertension
Controlled Education Of Patients After Stroke
The main objective of the study is to compare the benefit of optimised follow-up by nursing personnel from the vascular neurology department, including therapeutic follow-up and an educational program directed to the patient and…
- Trial name
- CEOPS (NCT02132364)
- Testing
- optimised follow-up
- Where
- 17 sites in France
- Volunteers
- 290 people
- Sponsor
- University Hospital, Lille
Cervical Artery Dissection, Carotid Artery Dissection
To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection
This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants…
- Conditions
- Cervical Artery Dissection, Carotid Artery Dissection, Vertebral Artery Dissection, Stroke
- Trial name
- CADISS (NCT00238667)
- Testing
- Antiplatelet (Aspirin, Dipyridamole, clopidogrel), Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- St George's, University of London
Spasticity, Muscle
Dry Needling and Botulinum Toxin in the Management of Poststroke Spasticity
Stroke is a clinical picture that can result in loss of motor, sensory and cognitive functions or coma. Approximately 75% of stroke survivors develop disability and one of the causes of disability is the presence of spasticity.
- Trial name
- NCT03747900
- Testing
- Botulinum Toxin Type A, Botulinum Toxin Type A and dry needling.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Stroke
Attendance and Adherence to Aerobic Exercise After Stroke
Stroke is a common cause of functional impairment and a disease that requires large financial resources and days of care(1). For a few years now, group or individual cardiorespiratory training has been a recommended part of…
- Trial name
- NCT07007507
- Testing
- Aerobic Exercise
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Ostergotland County Council, Sweden
Stroke, Healthy Adult
tVNS Responsiveness Testing With Pupil Size
The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults.
- Trial name
- NCT06335199
- Testing
- Unilateral Left tVNS stimulation, Bilateral tVNS stimulation, Unilateral Right tVNS stimulation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Stroke, Cerebrovascular
Reactive Standing Balance Step Training Post Stroke
The purpose of this study is to investigate the effectiveness of reactive step training on the timing and frequency of perturbation induced paretic leg stepping in persons post stroke.
- Trial name
- NCT05772936
- Testing
- Balance training
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwestern University
Stroke, Spasticity
Rectus Femoris Tenotomy Versus Botulinum Toxin A for Stiff Knee Gait After Stroke
Stiff knee gait is defined as the lack of knee flexion in the swing phase of gait. Stiff knee gait is a frequent condition among stroke patients leading to reduce gait speed and increase energy cost.
- Trial name
- NCT02114736
- Testing
- Tenotomy of the proximal rectus femoris tendon, Botulinum Toxin injection in the rectus femoris muscle
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital of Mont-Godinne
Stroke
Effects of BIONESS in Rehabilitation of Stroke
A four-weeks randomized clinical two-period crossover-design study will be conducted. Each patient will be randomized in a two separate consecutive treatment periods (Parallel Group Design).
- Trial name
- EFES-BIO-SEP (NCT04767360)
- Testing
- Bioness-300
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- LMU Klinikum
Stroke, Stroke, Acute
Earlier Mobilization Post Acute Thrombolysis
This is a phase III trial trying to determine whether 12-hour bed rest following IV thrombolysis therapy (i.e. tPA) for ischemic stroke is non-inferior to 24-hour bed rest by measure of outcomes on the modified Rankin Scale (mRS)…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- EMPATHY-I (NCT04153942)
- Testing
- Mobilization
- Sponsor
- Brian Silver
Stroke
Telemedicine's Utility for Augmenting Clinical Trials and Informed Consent TACTIC
This is a 6 year, Phase I, Clinical Research Protocol to study the feasibility of using a telemedicine system for performing research in a remote hospital system.
- Trial name
- NCT00390286
- Where
- United States
- Sponsor
- University of California, San Diego
Stroke
Reliability and Validity of The Figure of 8 Walk Test With and Without Dual-Task
For people with stroke, walking on a curved path is more difficult than walking on a straight path and can lead to falls. Most of the outcome scales assessing the gait of people with stroke involve walking in a straight line or…
- Trial name
- NCT06540482
- Testing
- Reliability test
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Afyonkarahisar Health Sciences University
Atrial Fibrillation (AF), Stroke
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation
The purpose of the ANT-006 study is to evaluate the bleeding profile of abelacimab relative to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.
- Trial name
- AZALEA-TIMI 71 (NCT04755283)
- Testing
- Abelacimab, Rivaroxaban
- Where
- 92 sites in United States, Canada and 5 more
- Volunteers
- 1,287 people
- Sponsor
- Anthos Therapeutics, Inc.
Stroke
Effect of tDCS on Upper Extremity After Strokes
The investigators hypothesize that transcranial direct current stimulation (tDCS) can improve upper limb motor recovery in the sub-acute phase of stroke patients.
- Trial name
- NCT02987361
- Testing
- DC-STIMULATOR PLUS
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Chonbuk National University Hospital
Traumatic Brain Injury, Ischemic Stroke
Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor
The goals of the project are to evaluate a noninvasive monitor of brain metabolism and blood flow in critically ill humans. If validated, such a reliable noninvasive brain blood flow and metabolism monitor, by allowing…
- Conditions
- Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- NNOM (NCT02983786)
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Pennsylvania
Stroke
Perfusion Enhancement With Respiratory Impedance in Stroke (PERI-Stroke)
This is a non-randomized phase 2 study designed to asses the mean flow velocity (MFV) and cerebral blood flow (CBF) response to non-invasive respiratory impedance.
- Trial name
- PERI-Stroke (NCT03476954)
- Testing
- Respiratory Impedance (RI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
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