Clinical trials: Cerebrovascular Apoplexy
Post-stroke Shoulder Pain
Repetitive Transcranial Magnetic Stimulation in Hemiplegic Shoulder Pain
Shoulder pain after stroke is one of the most common complications of stroke. Underlying mechanisms of shoulder pain after stroke still completely is not clarified.
- Trial name
- NCT05601921
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Izmir Katip Celebi University
Stroke
Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke
Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited.
- Trial name
- NCT01855633
- Testing
- Traditional Theta burst stimulation (TBS), Modified TBS rTMS
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Dongtan Sacred Heart Hospital
Stroke, Acute Ischemic Stroke
Mobilisation After Endovascular Stroke Treatment
The goal of this observational study is to learn how the timing of mobilisation after endovascular thrombectomy (EVT) affects complications in patients with acute ischaemic stroke.
- Conditions
- Stroke, Acute Ischemic Stroke, Acute Ischemic Stroke AIS, Endovascular Thrombectomy
- Trial name
- MAESTRO (NCT07860333)
- Testing
- Mobilisation
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Ischemic Stroke
Evaluation of the Safety and Performance of Magneto Microcatheter
A prospective, open label single arm feasibility study to evaluate the safety and performance of the Magneto Microcatheter in patients diagnosed with acute ischemic stroke and planned for thrombectomy procedure.
- Trial name
- NCT04466033
- Testing
- Magneto Microcatheter
- Where
- 3 sites in Hungary, Israel
- Volunteers
- 4 people
- Sponsor
- Magneto Thrombectomy Solutions
Cerebrovascular Accident
Use of a Mechanically Passive Rehabilitation Device in Vietnam: Impact on Upper Extremity Hemiparesis After Stroke
The goal of this project is to test a device (Zondervan et al, 2013) that can provide active assistance for arm training for people in Vietnam with severe to moderate stroke, but that is also simple and does not rely on powered…
- Trial name
- NCT02327767
- Testing
- Resonating Arm Exerciser
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- California State University, Northridge
Ischemic Stroke, Haemorrhagic Stroke
COAgulation Disorders in Ischaemic and Haemorrhagic Stroke
In this study the investigators will assess both procoagulant and anticoagulant pathways using thrombin generation and platelet function tests; as well as neuronal ischemia using cell free DNA in all patients presenting with…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- COADIHS (NCT05974111)
- Testing
- blood sampling
- Where
- Belgium
- Volunteers
- 379 people
- Sponsor
- Ziekenhuis Oost-Limburg
Ischemic Stroke
Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)
The current guideline recommends to give antithrombotic treatment 24 hours after intravenous thrombolysis in acute ischemic stroke.
- Trial name
- NCT05193071
- Testing
- Aspirin 100mg; Clopidogrel 300mg
- Where
- 2 sites in China
- Volunteers
- 1,022 people
- Sponsor
- General Hospital of Shenyang Military Region
Ischemic Stroke, Acute, Stroke
NeuroGlove fMRI Study
This is a prospective, single center, interventional clinical study containing two cohorts the treatment cohort and control cohort. A total of 13 subjects will be enrolled.
- Trial name
- NCT05961293
- Testing
- NeuroGlove
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
Psychosocial, Narrative
Psychosocial Wellbeing Following Stroke
The purpose of this feasibility study is to develop and initially test a dialogue-based psychosocial intervention aimed at promoting coping and psychosocial wellbeing following an acute stroke.
- Conditions
- Psychosocial, Narrative, Coping, Quality of Life
- Trial name
- NCT01912014
- Testing
- Psychosocial support and counselling
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- University of Oslo
Stroke
Clinical Study of the Efficacy and Safety of Spinal Cord Stimulation in Patients With Limb Motor Dysfunction Following Stroke
To assess the efficacy and safety of spinal cord stimulation in treating post-stroke limb motor disorders, we propose to conduct a clinical trial.
- Trial name
- NCT07627516
- Testing
- Spinal cord stimulator
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease, Atrial Fibrillation
Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS)
Antiplatelet therapy is indispensable for the prevention of stent thrombosis in patients who underwent coronary artery stenting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Stroke, Fetal Blood Loss
- Trial name
- REWRAPS (NCT02024230)
- Testing
- Rivaroxaban or Warfarin
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Fujita Health University
Acute Ischemic Stroke
Hemofiltration in Acute Ischemic Stroke
Ischemic stroke is accompanied by a three to four hundred percent increase in the brain's extracellular fluid (ECF) and cerebrospinal fluid (CSF) concentration of glutamate, which diffuses and damages surrounding neurons.
- Trial name
- HAISM (NCT03454867)
- Testing
- Hemofiltration, Standard acute ischemic stroke treatment
- Volunteers
- 37 people
- Sponsor
- University Medical Center, Kazakhstan
Stroke, Cancer
Mechanisms of Ischemic Stroke in Cancer Patients
The purpose of this study is to better understand the causes of stroke in people with cancer. Active cancer increases the risk of stroke.
- Trial name
- MOST-CA (NCT02604667)
- Testing
- Blood tests, Transcranial Doppler Microemboli Detection Study
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Weill Medical College of Cornell University
Stroke, Acute Cerebrovascular Accident
Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times.
- Conditions
- Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death
- Trial name
- NCT06253000
- Testing
- Cryoablation, Radiofrequency ablation
- Where
- Russia
- Volunteers
- 158 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Malignant Media Infarction, Stroke
Optic Nerve Sonography to Monitor Intracranial Pressure After Ischemic sTrokE - The ONSITE Study
The goal of the ONSITE study is to investigate whether an increase Optic nerve sheath diameter (ONSD) may help to predict intracranial hypertension (IH) after stroke.
- Conditions
- Malignant Media Infarction, Stroke, Intracranial Hypertension
- Trial name
- ONSITE (NCT06939114)
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- University of Zurich
Stroke, Acute
SPT-07A Injection in Patients With Acute Ischemic Stroke (AIS): A Phase III Clinical Trial
This is a multicenter, randomized, double-blind, placebo-controlled, parallel controlled clinical trial in Chinese patients with acute ischemic stroke.
- Trial name
- SPAIR-2 (NCT05159947)
- Testing
- SPT-07A injection
- Where
- China
- Volunteers
- 1,112 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Stroke
Independent Use of Brain Measurement-Based Rehabilitation System by Stroke Survivors
The Axem Home study is a randomized open label trial analyzing the safety and feasibility of coupling the Axem Home prototype device with exercise to improve motor recovery following a stroke.
- Trial name
- NCT05016193
- Testing
- Axem Home Prototype Device, Rehabilitation Exercise Program
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Traumatic Brain Injury, CVA (Cerebrovascular Accident)
The Brain Injury Neurorehabilitation Project
The primary objective of The Brain Injury Neurorehabilitation Project is a systematic effort to generate cutting edge research in brain injury and cognitive rehabilitation that will advance neurorehabilitation research.
- Trial name
- NCT06556316
- Testing
- Cognitive Intervention with the Categorization Program, Social Cognitive Communication Program, Non-Invasive Brain Stimulation with tDCS
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Ischemic Stroke
Neuroactive Steroids in Acute Ischemic Stroke
Despite several scientific and technological advances, there is no single neuroprotective treatment that can reverse the brain damage after acute ischemic stroke (AIS).
- Trial name
- NCT02914106
- Testing
- Observational Study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Militar Central, Argentina
Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease
Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)
This phase III trial compares the effect of adding tocilizumab to standard of care versus standard of care alone in treating cytokine release syndrome (CRS) in patients with SARS-CoV-2 infection.
- Conditions
- Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease, Chronic Renal Failure, Coronary Artery Disease
- Trial name
- NCT04361552
- Testing
- Best Practice, Tocilizumab
- Where
- United States
- Sponsor
- Emory University
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