Clinical trials: Cerebrovascular Apoplexy
Stroke, Non-communicable Disease
Make My Day - a Stroke Prevention Program
The purpose of this study is to evaluate the effects of a person-centered stroke prevention program implemented in primary healthcare.
- Trial name
- NCT05279508
- Testing
- Make My Day - stroke prevention program
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Karolinska Institutet
Stroke, Upper Limb Function
Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation
Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training.
- Trial name
- T-STAR (NCT06842095)
- Testing
- Transcranial Alternating Current Stimulation (beta-tACS)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Oxford
Spinal Cord Injuries, Stroke
Wheelchair Cushion Comparison Study: SAFETY
Purpose: To examine the safety of the use of two wheelchair cushions for healthy individuals with intact sensation and individuals post stroke and spinal cord injury with impaired sensation.
- Conditions
- Spinal Cord Injuries, Stroke, Healthy Adults
- Trial name
- NCT03430375
- Testing
- Alternating air wheelchair cushion, Static air cushion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke
Additional Effects of Motor Imaginary Technique Along With Task Oriented Trunk Control Training
The aim of this randomized controlled trial is determine additional effects of motor imagery technique along with task oriented training on trunk control, posture, balance and mobility.
- Trial name
- NCT06877819
- Testing
- Motor Imaginary Technique alongwith task-oriented training, Task Oriented Training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Stroke
Vitamin D and Stroke
Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin…
- Trial name
- NCT02916030
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Antiphospholipid Syndrome, Ischemic Stroke
Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKE
Antiphospholipid syndrome (APS) has a close association with ischemic stroke; however, the optimal treatment strategy for APS-related stroke has yet to be established.
- Conditions
- Antiphospholipid Syndrome, Ischemic Stroke, Transient Ischemic Attack, Cerebrovascular Disease
- Trial name
- APS-STROKE (NCT05995600)
- Testing
- Antiplatelet Drug, Warfarin
- Where
- 32 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Brain Ischemia, Stroke
Effects Of DP-b99 On Neurological Function In Subjects With Acute Ischemic Hemispheric Stroke
This study will examine if DP-b99 can improve neurological function (for example strength and coordination) in the 3 months after an acute stroke
- Conditions
- Brain Ischemia, Stroke, Cerebrovascular Disorders
- Trial name
- NCT00190047
- Testing
- DP-b99
- Where
- 22 sites in Germany, Israel
- Volunteers
- 150 people
- Sponsor
- D-Pharm Ltd.
Stroke
Increasing Physical Activity in Stroke Survivors Using STARFISH
There is good evidence of the effectiveness of regular physical activity in the primary and secondary prevention of stroke. STARFISH is a smartphone-based application designed as a behavioural change intervention to encourage the…
- Trial name
- NCT01792349
- Testing
- STARFISH intervention
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- NHS Greater Glasgow and Clyde
Acute Ischemic Stroke
Safety and Preliminary Efficacy of Hibernation-Like Therapy (Chlorpromazine and Promethazine) in Patients With Acute Ischemic Stroke (AIS) Eligible for Reperfusion Therapy.
This is a single-center, dose-escalation and dose-expansion Phase I study designed to evaluate the safety of hibernation-like therapy (Chlorpromazine and Promethazine, C+P) and observe improvements in infarct volume in patients…
- Trial name
- CHILL-S (NCT07364344)
- Testing
- Hibernation-like Therapy (Chlorpromazine and Promethazine, C+P)
- Volunteers
- 57 people
- Sponsor
- Ji Xunming,MD,PhD
Anticoagulation With Direct Oral Anticoagulants
Point-of-Care Testing of Coagulation in Patients Treated With Direct Oral Anticoagulants Extended
The investigators' study aims to test the correlation between CoaguChek point-of-care aPTT testing (Roche, Switzerland) and low plasma levels of all four currently EMA approved direct oral anticoagulants (DOAC; apixaban…
- Trial name
- POCT-DOAC ext (NCT04679298)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Tobacco Use Disorder
Smoking Termination Opportunity for inPatients
The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute smoking related illness, to assist patients through withdrawal by use of a…
- Trial name
- STOP (NCT01141855)
- Testing
- Champix, Counselling alone
- Where
- 3 sites in Australia
- Volunteers
- 392 people
- Sponsor
- The Queen Elizabeth Hospital
Spinal Cord Injury, Stroke
Brain/Neural Hand Exoskeleton Control for Restoration of Bimanual Tasks
This study investigates whether spinal cord injury and stroke survivors (n=10) are able to operate a brain/neural hand exoskeleton (B/NHE) based on electroencephalography (EEG) and electrooculography (EOG) for restoration of…
- Trial name
- NCT04440709
- Testing
- Brain/neural hand exoskeleton (B/NHE)
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- University Hospital Tuebingen
Stroke, Brain Computer Interface
BCI for Hemiparetic Upper Extremities in Patients Due to Stroke
Non-invasive brain-computer interface (BCI) technology is one of the new training approaches to achieve motor restoration through a closed-loop system from brain activity through event-related desynchronization (ERD) after motor…
- Trial name
- NCT05778448
- Testing
- Brain Computer Interface/ Functional Electrical Stimulation/ Virtual Reality
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Virtual Reality in Occupational Therapy Upper Limb Stroke Rehabilitation
The study aims to assess the feasibility of using Resynk, a virtual reality (VR) software platform for upper limb rehabilitation for stroke survivors, both in acute hospital settings and in the community (home, private nursing…
- Trial name
- NCT07032155
- Testing
- Resynk VR session, Using Resynk VR on stroke survivors
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- eXRt Intelligent Healthcare
Stroke
Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke Patients
Rehabilitative treatment in stroke survivors has shown to be effective in improving functional outcome and reducing dependency. Plasticity of the central nervous system, along with coping strategies and adaptations, seems to play…
- Trial name
- NCT00967408
- Testing
- Escitalopram, Rehabilitative treatment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Stroke
Repetitive Bihemispheric Transcranial Direct Current Stimulation After Stroke
Non-invasive repetitive bi-hemispheric transcranial direct current stimulation (tDCS) may restore post-stroke bi-hemispheric balance by increase peri-lesional cortex activity and suppress abnormal inhibition from non-lesional…
- Trial name
- NCT02731508
- Testing
- Bihemispheric transcranial direct current stimulation
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Ischemic Stroke, Intracranial Artery Occlusion
Rescue Stenting for Failed Endovascular Thrombectomy in Acute Ischemic Stroke (ReSET)
This study is a prospective, open-label, multi-center, registry study, designed to show that rescue stenting is safe and effective for emergency large vessel occlusion (ELVO) patients who have mechanical thrombectomy failure.
- Trial name
- NCT03993340
- Testing
- Rescue stenting
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Yonsei University
Non-valvular Atrial Fibrillation
Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
The purpose of this study are 1) to characterize the primary and secondary prevention patients, 2) to calculate incidence rates of stroke/SE or major bleeding in each cohort and 3) to investigate for Japanese secondary prevention…
- Trial name
- NCT05321810
- Testing
- Apixaban, Warfarin
- Where
- Japan
- Volunteers
- 193,565 people
- Sponsor
- Pfizer
Ischemic Stroke
Serial ECG Versus Holter to Detect Atrial Fibrillation in Elderly Ischemic Stroke Patients
Paroxysmal atrial fibrillation is often undetected because characteristics such as short duration, episodic, and frequently asymptomatic nature make it challenging to diagnose at the bedside, leading to suboptimal secondary…
- Trial name
- NCT02578979
- Testing
- Electrocardiogram, Holter
- Where
- 6 sites in Taiwan
- Volunteers
- 826 people
- Sponsor
- Chang Gung Memorial Hospital
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