Clinical trials: Cerebrovascular Disease
Stroke
Virtually Assisted Home Rehabilitation After Acute STroke (VAST-rehab)
The purpose of this study is to investigate the feasibility of a virtual education and virtual visit program in engaging patients with rehabilitation at home after stroke.
- Trial name
- VAST-rehab (NCT05659784)
- Testing
- Telerehabilitation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebrovascular Disorders, Smoking Cessation
Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease
Research Aims The aims of this research study are to determine whether cost-free smoking cessation pharmacotherapy: 1. Helps smokers with Transient Ischemic Attack (TIA) or stroke to quit smoking over the long-term, compared to…
- Trial name
- NCT00962988
- Testing
- Cost-Free Pharmacotherapy Group, Prescription Only Group
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiovascular Diseases, Carotid Stenosis
Recurrent Carotid Stenosis
To determine whether recurrent stenosis following carotid endarterectomy could be reduced by pre- and post-operative oral administration of platelet-inhibiting drugs.
- Conditions
- Cardiovascular Diseases, Carotid Stenosis, Cerebrovascular Disorders, Heart Diseases
- Trial name
- NCT00000527
- Testing
- aspirin, dipyridamole
- Sponsor
- Emory University
Dysphagia, Swallowing Disorders
Motor Learning in Dysphagia Rehabilitation
The overall goal is to exploit motor learning principles and adjuvant techniques in a novel way to enhance dysphagia rehabilitation.
- Conditions
- Dysphagia, Swallowing Disorders, Deglutition Disorders, Stroke
- Trial name
- NCT02576470
- Testing
- Biofeedback, Transcranial Direct Current Stimulation, Financial Reward
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Subdural Hematoma
Effect and Safety Study of Atorvastatin to Treat Chronic Subdural Hematoma
To evaluate the clinic effects and security of oral administration of Atorvastatin on chronic subdural hematoma (CSDH).
- Trial name
- NCT02024373
- Testing
- Atorvastatin
- Where
- 31 sites in China
- Volunteers
- 200 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
Intracranial Arteriosclerosis, Ischemic Preconditioning
Remote Ischemic Conditioning Combined With Endovascular Stenting for Symptomatic Intracranial Atherosclerotic Stenosis
The purpose of this registry is to evaluate the safety and efficacy of RIC for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) undergoing endovascular therapy.
- Conditions
- Intracranial Arteriosclerosis, Ischemic Preconditioning, Endovascular Procedures
- Trial name
- NCT05653505
- Testing
- Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Huanhu Hospital
Venous Sinus Thrombosis, Cranial
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding…
- Trial name
- NCT05413837
- Testing
- anotomy and variation of venous sinus, the level of biomarker in bood
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Cerebrovascular Accident
Use of the BrainPort® Balance Device to Improve Balance in Adults With Balance Deficits Due to Stroke
The purpose of this study is to evaluate the safety and efficacy of the BrainPort balance device in improving balance in people with balance deficits due to stroke.
- Trial name
- NCT00567944
- Testing
- BrainPort Balance Device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Wicab
Stroke, Sleep
Personalised Sleep and Circadian Intervention After Stroke
This is a two-arm, parallel-group randomized controlled feasibility trial involving 40 community-dwelling adults with chronic stroke and ongoing sleep or circadian difficulties.
- Trial name
- NCT07731516
- Testing
- ISleepFAST, Stroke and Sleep Health Education
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Effect of Transcranial Direct Current Stimulation (tDCS) on Post-stroke Patients on Neuromotor Recovery
The aim of the study is to evaluate whether a non-invasive brain stimulation technique (Transcranial Direct Current Stimulation) can influence the secondary neurodegeneration observed after a stroke (assessed based on serum…
- Trial name
- NCT05821816
- Testing
- tDCS, Conventional rehabilitative treatment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke
Micro-embolic Signals Detection With Transcranial HOLter in Acute Ischemic STroke
In acute ischemic stroke, the identification of an etiology is of major importance to prevent recurrence by providing the best treatment.
- Trial name
- HOLISTER (NCT02762552)
- Testing
- Transcranial-holter monitoring
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Bordeaux
Sneddon Syndrome
Genetic Risk Factors of the Sneddon Syndrome
Sneddon syndrome (SS) is a rare disorder with an incidence of about 4/million/year that affects mainly young and predominantly female adults.
- Trial name
- NCT06850519
- Testing
- Exome Sequencing and Sanger Sequencing
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karl Landsteiner University of Health Sciences
Subcortical Lesions, Stroke
Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke
This study aims to develop imaging-based biomarkers to assess which chronic stroke participant with lower extremity disability may respond or resist high intensity interval training (HIIT).
- Trial name
- NCT07663292
- Testing
- HIIT intervention
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Emory University
Intracranial Pressure Increase, Posterior Fossa Lesion
Infra- and Supratentorial Neuromonitoring
Invasive neuromonitoring of intracranial pressure (ICP) is an important element of neurosurgical critical care that is used primarily as an indicator of adequate cerebral perfusion in patients, when clinical observation is not an…
- Conditions
- Intracranial Pressure Increase, Posterior Fossa Lesion, Posterior Fossa Hemorrhage
- Trial name
- DUAL-ICP (NCT05346471)
- Testing
- Multimodal neuromonitoring
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University Innsbruck
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
Swiss SOS MoCA - DCI Study
The primary objective of this multicenter observational study is to determine the effect size of the relationship between DCI and neuropsychological impairment 14-28 days and 3 months after aSAH.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Stroke, Complication
- Trial name
- NCT03032471
- Testing
- There is no intervention for this study. Patients are allocated to the study groups based on whether or not DCI occurs.
- Where
- 6 sites in Switzerland
- Volunteers
- 128 people
- Sponsor
- Swiss SOS Study Group
Stroke, Patent Foramen Ovale
AMPLATZER PFO Occluder Post Approval Study
The purpose of this single arm, multi-center study is to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder in the post Approval Setting.
- Trial name
- PFO PAS (NCT03309332)
- Testing
- AMPLATZER™ PFO Occluder
- Where
- 88 sites in United States, Canada and 5 more
- Volunteers
- 1,214 people
- Sponsor
- Abbott Medical Devices
Acute Stroke
Exploring Psychometric Properties of a New Version of the 6MWT in the Acute Stroke Population
The purpose of this study is to assess inter- and intra-rater reliability of the 6MWT in people with acute stroke who require various levels of assistance with walking.
- Trial name
- NCT04515693
- Testing
- 6 Minutes Walking Test
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Aging
Affordable Mobile Robots for the Elderly
This project develops and tests the use of service robots to track health of the elderly over time. The objectives are to develop a low-cost mobile manipulator capable of a limited set of elder- relevant manipulation tasks (e.g.
- Trial name
- NCT02807506
- Testing
- Mobile Service Robot, Survey
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Hand Rehabilitation Based on a RobHand Exoskeleton in Stroke Patients: a Case Series Study
The following study seeks to provide information regarding to the RobHand exoskeleton for hand neuromotor maintenance and/or rehabilitation, developed by the University of Valladolid, Spain.
- Trial name
- NCT05598892
- Testing
- Training with Robotic Hand Exoskeleton
- Where
- Chile
- Volunteers
- 4 people
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Chronic Disease, Frail
Functional Exercise and Nutrition Education Program for Older Adults
There is strong evidence that specific types of exercise can improve health and physical function in older adults. While community exercise classes exist, many older adults with chronic conditions may need guidance from…
- Conditions
- Chronic Disease, Frail, Diabetes Mellitus, Cancer
- Trial name
- MoveStrong (NCT04037436)
- Testing
- Strength and Balance Training & Nutrition Education, Usual Care
- Where
- 5 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Waterloo
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