Clinical trials: Cerebrovascular Disease
Aortic Diseases, Cardiac Surgical Procedures
Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery
In ascending aortic surgery the distal anastomosis may be constructed with the aortic cross-clamp maintained, or, where the extent of the aortic pathology and the geometry of the graft require it, after release of the cross-clamp…
- Conditions
- Aortic Diseases, Cardiac Surgical Procedures, Aortic Aneurysm, Thoracic, Delirium - Postoperative
- Trial name
- SACP-ONSD (NCT07800806)
- Testing
- Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Cardiovascular Diseases, Stroke
Hybrid Stroke Rehab With Mirror Priming
This trial aims to examine the effects of enhanced mirror priming, overcoming the limitations of traditional mirror therapy, to achieve optimization and personalized intervention.
- Conditions
- Cardiovascular Diseases, Stroke, Cerebrovascular Disorders
- Trial name
- NCT07324278
- Testing
- Mirror priming, Conventional therapy
- Where
- Taiwan
- Volunteers
- 81 people
- Sponsor
- I-Shou University
Intraventricular Hemorrhage, Intracerebral Hemorrhage
The Natural History of Procalcitonin in Hemorrhagic Stroke
Approximately 12% of strokes in the United States are hemorrhagic.1 Hemorrhagic stroke can lead to multiple complications including fever that is not infectious.
- Trial name
- NCT01498705
- Testing
- Procalcitonin level
- Where
- United States
- Sponsor
- CAMC Health System
Stroke, Stroke, Acute
PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute Stroke
The investigators recently identified Brain-derived tau (BD-tau) as a sensitive blood-based biomarker for brain injury in acute ischemic stroke: in patients with acute ischemic stroke, plasma BD-tau was associated with…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Cerebrovascular Disorders
- Trial name
- PROMISE-BD-100 (NCT06121336)
- Testing
- Plasma levels of BD-tau
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke, Cerebrovascular Disease
Functional Changes and Home Discharge After Inpatient Stroke Rehabilitation
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation…
- Trial name
- NCT07502326
- Testing
- Inpatient Rehabilitation
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- SeongKi Min
Stroke, Cardiovascular Diseases
MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway
Annually 13000 Norwegians experience an ischemic stroke. The number of stroke is anticipated to increase with 50% within 2030 due to a growing number of elderly.
- Conditions
- Stroke, Cardiovascular Diseases, Cardiovascular Risk Factor, Brain Ischemia
- Trial name
- NCT03962127
- Testing
- no intervention
- Where
- 8 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Norwegian University of Science and Technology
Intracranial Aneurysms
PMCF Registry to Describe the Safety and Performance of p64, p48 MW and p64 MW in France
To evaluate safety and performance of the phenox GmbH Flow Diverter p64, p64 MW, and p48MW in France, this registry will include subjects with intracranial aneurysms (anterior and posterior) who are treated with a phenox GmbH…
- Trial name
- CEFloW (NCT07748572)
- Testing
- Aneurysm treatment with a Flow Modulation Device
- Where
- 11 sites in France
- Volunteers
- 200 people
- Sponsor
- Phenox GmbH
Ischemic Stroke, Ischemic Cerebrovascular Disease
Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease
The goal of this single-center prospective observational study is to identify and evaluate new biomarkers for ischemic cerebrovascular disease (ICVD) to aid in early diagnosis, individualized treatment planning, and prognosis…
- Trial name
- NCT06890702
- Testing
- biomaker levels
- Where
- 2 sites in China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Spinal Cord Diseases, Spinal Cord Injuries
Optimization of Adaptive Rowing Seating
Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities.
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neurodegenerative Disorders, Cerebrovascular Accident With Associated Sequelae
- Trial name
- OARS (NCT07099625)
- Testing
- Adaptive Indoor Rowing Seat, Paddle Sport adaptive seating system
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Intracerebral Hemorrhage
A Study to Evaluate the Safety, Tolerability and the Effects of Ixodes Ricinus-Contact Phase Inhibitor (Ir-CPI) in Adult Patients With Spontaneous Intracerebral Haemorrhage
The purpose of the study is to provide a first assessment of safety, tolerability and efficacy of Ir-CPI, administered on top of standard-of-care, on secondary brain injury in patients with spontaneous intracerebral haemorrhage.
- Trial name
- BIRCH (NCT05970224)
- Testing
- Ir-CPI
- Where
- 8 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- Bioxodes S.A.
Cardiovascular Diseases, Diabetes Mellitus
Nurses' Health Study (Cardiovascular Component)
To determine the relationships of hormonal, reproductive, dietary, and lifestyle factors, as well as biochemical and genetic factors, with the subsequent risk of coronary heart disease and other cardiovascular events in a cohort…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Coronary Disease, Heart Diseases
- Trial name
- NCT00005152
- Volunteers
- 121,700 people
- Sponsor
- Brigham and Women's Hospital
Intracerebral Haemorrhage, Paediatric Stroke
Master Study Protocol for the Cohort of the Specialist Network Stroke (SN Stroke)(Stroke-CORE)
The Stroke-CORE cohort aims to provide a comprehensive and up-to-date understanding of stroke care in Germany. To achieve this, patients are followed along the entire continuum of care-from initial management before hospital…
- Conditions
- Intracerebral Haemorrhage, Paediatric Stroke, Stroke Acute, Stroke
- Trial name
- Stroke-CORE (NCT07553650)
- Where
- 12 sites in Germany
- Volunteers
- 12,750 people
- Sponsor
- Charite University, Berlin, Germany
Ischemic Stroke, Ischemic Stroke, Acute
Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke)
Patients with ischemic stroke commonly receive antiplatelet therapy, frequently starting as dual antiplatelet therapy, which is associated with an increased risk of gastrointestinal complications.
- Conditions
- Ischemic Stroke, Ischemic Stroke, Acute, Transient Ischemic Attack (TIA), Cerebrovascular Disease
- Trial name
- TegoStroke (NCT07687706)
- Testing
- Tegoprazan 50 mg
- Where
- 24 sites in South Korea
- Volunteers
- 1,524 people
- Sponsor
- Hanyang University Guri Hospital
Post Stroke Epilepsy, Stroke
Predisposing Factors for Post-stroke Epilepsy
The goal of this observational study is to learn about epilepsy after a stroke (post-stroke epilepsy). The main questions it aims to answer are: What make some patients develop epilepsy after a stroke? Does sleep have an impact…
- Conditions
- Post Stroke Epilepsy, Stroke, Epilepsy, Seizures
- Trial name
- PRESTEP (NCT05864547)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Intracerebral Hemorrhage
Auricular VNS Following Intracerebral Hemorrhage
This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.
- Trial name
- NCT06799390
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Washington University School of Medicine
Stroke
Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities.
- Trial name
- NCT07681102
- Testing
- kTMP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Magnetic Tides
Stroke
Pilot Study: A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities.
- Trial name
- NCT06317194
- Testing
- kTMP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Magnetic Tides
Nervous System Diseases, Cerebrovascular Disorders
Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage
MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard…
- Conditions
- Nervous System Diseases, Cerebrovascular Disorders, Cardiovascular Diseases, Vascular Diseases
- Trial name
- MSU-ICH (NCT07665827)
- Testing
- Mobile Stroke Unit Management, Standard Management
- Where
- China
- Volunteers
- 706 people
- Sponsor
- Xuanwu Hospital, Beijing
Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Hemodynamic Parameters in People With Atherosclerotic Vascular Disease Referred to a Secondary Prevention and Cardiovascular Rehabilitation Program
The main purpose of this study is to evaluate the hemodynamic changes in the forefoot of patients with coronary, cerebrovascular or peripheral atherosclerotic disease referred a 12-week cardiovascular rehabilitation program (PREV…
- Conditions
- Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Cerebrovascular Atherosclerosis
- Trial name
- NCT06701032
- Testing
- Cardiovascular rehabilitation program
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Laval University
Stroke, Able Bodied
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons.
- Trial name
- NCT07401186
- Testing
- Bipolar Neural Stimulation Electrode
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Peter C. Gerszten, MD