Clinical trials: Cerebrovascular Disease
Stroke
Virtual Action Planning in Stroke: a Control Rehabilitation Study
Background : The general experience with the Virtual Reality application approach suggests that this treatment concept is promising in stroke rehabilitation Purpose : In shopping activity in a real supermarket and in simulated…
- Trial name
- VAPS REHAB (NCT01365858)
- Testing
- Rehabilitation
- Where
- 7 sites in France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Bordeaux
Ischemic Stroke
Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial
The purpose of this study is to compare the safety and efficacy of treating individuals with acute ischemic stroke with normobaric oxygen therapy (NBO, given within 9 hours of symptom onset), to standard medical treatment.
- Trial name
- NCT00414726
- Testing
- NBO (Normobaric Oxygen), Room Air
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Massachusetts General Hospital
Stroke
Comparing Different Montages of tDCS Combined With Dual-task Training on EEG Microstates
This study investigates whether electroencephalographic (EEG) measures of functional connectivity of the target network are associated with the response to different sets of transcranial direct current stimulation combined with…
- Trial name
- NCT05547126
- Testing
- Transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Paraíba
Stroke ( 3 Months After Onset), Stroke in Patients: New Tool to Evaluate the Impact in Their Life
Radiofrequency vs. Ultrasound Therapy for Shoulder Joint in Stroke Patients: A Comparative Clinical Trial
The purpose of the current study is to: Compare between radiofrequency (TECAR) therapy and ultrasound on Shoulder Pain, Range of Motion and Functional Outcome in Patients with stroke.
- Trial name
- TECAR (NCT07131943)
- Testing
- Radiofrequency, Ultrasound, The designed physical therapy program
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Stroke, Spatial Neglect
Evaluation of an Adaptive Computerized Training for Rehabilitation of Spatial Neglect in Stroke Survivors
The aim of this study is to investigate the effect of training with an adaptive computer game, in comparison to standard training, in the rehabilitation of stroke survivors suffering from spatial neglect.
- Conditions
- Stroke, Spatial Neglect, Neglect, Hemispatial, Attention Impaired
- Trial name
- MULTITASK (NCT04227132)
- Testing
- Adaptive computer game training, Standard computerized training
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke
Acute Effects of Whole Body Vibration in Chronic Stroke
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate…
- Trial name
- NCT01211093
- Testing
- High frequency whole body vibration, Low frequency whole body vibration, control
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Aphasia, Stroke
Can Listening to Music Improve Attention and Language After Post-Stroke Aphasia?
The goal of this clinical trial is to learn if a music-based intervention can acutely improve three types of attention (alerting, orientating, executive control) in people with aphasia following a stroke.
- Conditions
- Aphasia, Stroke, Stroke and Aphasia, Stroke Hemorrhagic
- Trial name
- NCT07198048
- Testing
- Music-Based Therapy for Post Stroke Aphasia, Audiobook Intervention for Post Stroke Aphasia
- Volunteers
- 45 people
- Sponsor
- Purdue University
Stroke
Effectiveness of Shock Wave Therapy for Upper Limb Spasticity
Introduction: Shock wave therapy (SWT) has a potential interest to treat spasticity. However, the pathophysiology of this treatment remains unknown.
- Trial name
- NCT04316026
- Testing
- shock wave therapy
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Patent Foramen Ovale, PFO
The Effect of Device Closure of Patent Foramen Ovale in Elderly Patients With Crytogenic Stoke/TCI
The primary objective is to evaluate if patent foramen ovale (PFO) closure and antiplatelet medical management can reduce the risk of recurrent stroke or transient ischemic attack (TIA) when compared to antiplatelet medical…
- Conditions
- Patent Foramen Ovale, PFO, Stroke, TIA
- Trial name
- CryptoCard (NCT01018355)
- Testing
- Percutaneous device closure of patent foramen ovale
- Where
- Denmark
- Volunteers
- 3,000 people
- Sponsor
- Hillerod Hospital, Denmark
Stroke, Intracerebral Hemorrhage Lobar
Neuroendoscopic Hematoma Evacuation Combined With Methylprednisolone Sodium Succinate in the Treatment of Lobar Intracerebral Hemorrhage at the Early Stage.
The aim of this trial is to investigate whether neuroendoscopic hematoma evacuation combined with early use of methylprednisolone sodium succinate can improve the efficacy and safety in the treatment with that of simple…
- Conditions
- Stroke, Intracerebral Hemorrhage Lobar, Methylprednisolone, Surgery
- Trial name
- HEMS (NCT06921616)
- Testing
- Simple neuroendoscopic hematoma evacuation, Neuroendoscopic hematoma evacuation combined with sodium methylprednisolone succinate
- Where
- China
- Volunteers
- 396 people
- Sponsor
- Yong Jiang
Stroke, Cerebral Palsy
Modulation of Brain Plasticity After Perinatal Stroke
Newborn stroke is the leading cause of a common type of cerebral palsy (CP) that affects thousands of Canadian children and families.
- Trial name
- PLASTIC CHAMPS (NCT01189058)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Constraint-induced movement therapy (CIMT)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Chronic Subdural Hematoma
A Prospective Randomized Study Evaluating the Recurrence Rate of Chronic Subdural Hematoma After Placing a Subperiosteal Drainage Compared to a Subdural Drainage
The aim of our study is to investigate in randomized controlled fashion whether the recurrence and complication rate, after insertion of subperiosteal drainage in the treatment of chronic subdural haematoma, is higher compared to…
- Trial name
- NCT01869855
- Testing
- Subdural Drainage, Subperiosteal Drainage
- Where
- 2 sites in Switzerland
- Volunteers
- 220 people
- Sponsor
- Kantonsspital Aarau
Cerebro-vascular Accident
Effect of Supervised Versus Unsupervised Strength Training on Balance and Functional Performance Among Post Stroke Ambulatory Patients
Objective: This single-blinded randomized controlled trial compared the effects of supervised clinic-based versus unsupervised home-based balance and strength training on functional outcomes in ambulatory post-stroke patients.
- Trial name
- RCT (NCT07010185)
- Testing
- home based exercise
- Where
- Saudi Arabia
- Volunteers
- 61 people
- Sponsor
- Majmaah University
Post-Acute-Stroke Rehabilitation
Effectiveness of a Wearable Device-based Assisted Post-stroke Rehabilitation System
Multidisciplinary rehabilitation facilitates functional recovery after stroke, and adherence to rehabilitation guidelines is associated with improved outcomes.
- Trial name
- NCT04997408
- Testing
- Customized exercise app, In-person therapist-supervised rehabilitation
- Volunteers
- 140 people
- Sponsor
- Landseed Hospital
Stroke, Spasticity
Effectiveness of Dry Needling (DNHS Technique) in Patients With Chronic Stroke
Study hypothesis: The DNHS technique, performed via one session of deep dry needling of myofascial trigger points applied to the biceps brachii, brachialis, flexor digitorum superficialis, flexor digitorum profundus, triceps…
- Trial name
- NCT03546517
- Testing
- Dry Needling
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidad San Jorge
Covid19, Corona Virus Infection
Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events
An estimated 22% of the global population is at an increased risk of a severe form of COVID-19, while one in four coronavirus patients admitted to intensive care unit will develop a pulmonary embolism.
- Conditions
- Covid19, Corona Virus Infection, Thrombosis, ARDS
- Trial name
- iGenes-COVID19 (NCT04519398)
- Testing
- Complete thrombophilic profile testing by multiplex PCR
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Cerebral Infarction
Efficacy and Safety of Cilostazol for the Indication of CSPS
This is a multicenter, open-label, prospective study of cilostazol use for prevention of recurrence in patients with cerebral infarction.
- Trial name
- NCT00216749
- Where
- South Korea
- Volunteers
- 650 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
ESRD
Fabry Disease Screening in ESRD Patients in West of France
Screening of Fabry disease in end-stage renal disease (ESRD) patients on dialysis or transplant in west of France.
- Trial name
- SNOUFY (NCT02719249)
- Testing
- Dried blood spot test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Rennes University Hospital
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