Clinical trials: Cerebrovascular Disease
Cardiovascular Diseases, Hypertension
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform designed to increase diversity in cardiovascular…
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke
- Trial name
- CONNECT (NCT06347484)
- Testing
- EHR-informed Recruitment Method of Contact, Educational Text-Messages and Connection to Cardiovascular Research Opportunities
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke
Augmentation of Locomotor Adaptation Post-Stroke
This project will evaluate two different methods of normalizing the center of mass acceleration (COMa) in individuals post-stroke, specifically focusing on rates and pattern of recovery to analyze walking-specific adaptations as…
- Trial name
- NCT02892084
- Testing
- tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke
Circuit Class Training vs. Individual, Task Specific Training in Chronic Stroke Patient
Due to minimal volitional activation of the impaired arm, these individuals are less able to engage in activities of daily living (ADL's). Moreover, simultaneous use of the hand and arm are needed throughout ADL's.
- Trial name
- NCT05059704
- Testing
- Circuit Class Training, Individual Task specific training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Stroke
Neural Mobilization for Reduction of Spasticity in Stroke
Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and…
- Trial name
- NCT05314465
- Testing
- Median nerve mobilization
- Where
- 3 sites in India
- Volunteers
- 7 people
- Sponsor
- Asir John Samuel
Stroke
Virtual Reality Software for Patients With Stroke
The goal os this clinical trial is to develop and validate a gamified, fully immersive, and stroke-specific virtual reality software to improve physical disability and quality of life in patients with stroke.
- Trial name
- RESET (NCT06132399)
- Testing
- META QUEST 3 virtual reality glasses, Nintendo Switch (Nintendo Co., Ltd, Kyoto, Japan), Usual care
- Where
- 4 sites in Spain
- Volunteers
- 96 people
- Sponsor
- Universidad de Almeria
Myocardial Infarction, Stroke
My Research Legacy Pilot Study
The My Research Legacy Pilot Study will establish a participant registry that collects self-reported health data and answers to online survey questions about individual daily choices, diets, and exercise; data from wearable…
- Conditions
- Myocardial Infarction, Stroke, Cardiomyopathy, Dilated, Systolic Heart Failure
- Trial name
- NCT02958098
- Volunteers
- 2,267 people
- Sponsor
- American Heart Association
Vascular Dementia
Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia
The purpose of this study is to examine the efficacy and safety of cholinesterase inhibitor (donepezil hydrochloride) Aricept in patients with vascular dementia (VaD).
- Trial name
- NCT00165763
- Testing
- donepezil hydrochloride (Aricept)
- Where
- 2 sites in Philippines
- Volunteers
- 36 people
- Sponsor
- Eisai Inc.
Brain Ischemia
Informative of Surface Electromyography and Prognostic Factors in Assessing the Recovery of Balance and Gait After Stroke
The aim of the biomedical research is to determine the informativeness and prognostic factors of surface electromyography by assessing the probability of recovery of balance and gait parameters in the second stage of…
- Trial name
- NCT04981184
- Testing
- Gait and balance measurement
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Stroke, Apraxias
Trial Using CogWatch for Tea Making Training in Stroke Apraxia and Action Disorganisation Syndrome
Apraxia and action disorganization syndrome after stroke can disrupt activities of daily living (ADL). Occupational therapy has been effective in improving ADL performance, however, inclusion of multiple tasks means it is unclear…
- Trial name
- CogWatchTea (NCT04044911)
- Testing
- Task model (CogWatch)
- Volunteers
- 29 people
- Sponsor
- University of Birmingham
Post-stroke Shoulder Pain
Repetitive Transcranial Magnetic Stimulation in Hemiplegic Shoulder Pain
Shoulder pain after stroke is one of the most common complications of stroke. Underlying mechanisms of shoulder pain after stroke still completely is not clarified.
- Trial name
- NCT05601921
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Izmir Katip Celebi University
Stroke
Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke
Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited.
- Trial name
- NCT01855633
- Testing
- Traditional Theta burst stimulation (TBS), Modified TBS rTMS
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Dongtan Sacred Heart Hospital
Stroke, Acute Ischemic Stroke
Mobilisation After Endovascular Stroke Treatment
The goal of this observational study is to learn how the timing of mobilisation after endovascular thrombectomy (EVT) affects complications in patients with acute ischaemic stroke.
- Conditions
- Stroke, Acute Ischemic Stroke, Acute Ischemic Stroke AIS, Endovascular Thrombectomy
- Trial name
- MAESTRO (NCT07860333)
- Testing
- Mobilisation
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Ischemic Stroke
Evaluation of the Safety and Performance of Magneto Microcatheter
A prospective, open label single arm feasibility study to evaluate the safety and performance of the Magneto Microcatheter in patients diagnosed with acute ischemic stroke and planned for thrombectomy procedure.
- Trial name
- NCT04466033
- Testing
- Magneto Microcatheter
- Where
- 3 sites in Hungary, Israel
- Volunteers
- 4 people
- Sponsor
- Magneto Thrombectomy Solutions
Cerebrovascular Accident
Use of a Mechanically Passive Rehabilitation Device in Vietnam: Impact on Upper Extremity Hemiparesis After Stroke
The goal of this project is to test a device (Zondervan et al, 2013) that can provide active assistance for arm training for people in Vietnam with severe to moderate stroke, but that is also simple and does not rely on powered…
- Trial name
- NCT02327767
- Testing
- Resonating Arm Exerciser
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- California State University, Northridge
Ischemic Stroke, Haemorrhagic Stroke
COAgulation Disorders in Ischaemic and Haemorrhagic Stroke
In this study the investigators will assess both procoagulant and anticoagulant pathways using thrombin generation and platelet function tests; as well as neuronal ischemia using cell free DNA in all patients presenting with…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- COADIHS (NCT05974111)
- Testing
- blood sampling
- Where
- Belgium
- Volunteers
- 379 people
- Sponsor
- Ziekenhuis Oost-Limburg
Ischemic Stroke
Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)
The current guideline recommends to give antithrombotic treatment 24 hours after intravenous thrombolysis in acute ischemic stroke.
- Trial name
- NCT05193071
- Testing
- Aspirin 100mg; Clopidogrel 300mg
- Where
- 2 sites in China
- Volunteers
- 1,022 people
- Sponsor
- General Hospital of Shenyang Military Region
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Ischemic Stroke, Acute, Stroke
NeuroGlove fMRI Study
This is a prospective, single center, interventional clinical study containing two cohorts the treatment cohort and control cohort. A total of 13 subjects will be enrolled.
- Trial name
- NCT05961293
- Testing
- NeuroGlove
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
Psychosocial, Narrative
Psychosocial Wellbeing Following Stroke
The purpose of this feasibility study is to develop and initially test a dialogue-based psychosocial intervention aimed at promoting coping and psychosocial wellbeing following an acute stroke.
- Conditions
- Psychosocial, Narrative, Coping, Quality of Life
- Trial name
- NCT01912014
- Testing
- Psychosocial support and counselling
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- University of Oslo
Stroke
Clinical Study of the Efficacy and Safety of Spinal Cord Stimulation in Patients With Limb Motor Dysfunction Following Stroke
To assess the efficacy and safety of spinal cord stimulation in treating post-stroke limb motor disorders, we propose to conduct a clinical trial.
- Trial name
- NCT07627516
- Testing
- Spinal cord stimulator
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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