Clinical trials: Cerebrovascular Diseases
Implementation Science, Stroke
Embedding the Fugl-Meyer Assessment in Occupational Therapists' Routine Practice
Background: Using outcome measures is emphasized in foundational training and clinical practice guidelines, but less than 50% of rehabilitation professionals consistently use outcome measures in practice.
- Trial name
- NCT05374239
- Testing
- Multi-component implementation intervention
- Where
- Singapore
- Volunteers
- 4 people
- Sponsor
- Singapore General Hospital
Stroke, Acute Cerebrovascular Accident
Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times.
- Conditions
- Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death
- Trial name
- NCT06253000
- Testing
- Cryoablation, Radiofrequency ablation
- Where
- Russia
- Volunteers
- 158 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Stroke
Effects of Upper Extremity Physiotherapy and Home Exercises on Functional Outcomes in Individuals With Stroke
This study aims to investigate the effects of an upper extremity physiotherapy program combined with home exercises on activities of daily living, quality of life, joint range of motion, and pain in individuals with hemiplegia…
- Trial name
- NCT07915141
- Testing
- Supervised Upper Extremity Physiotherapy Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Gelisim University
Transient Ischemic Attack, Vascular Cognitive Impairment
Reshaping the Path of Vascular Cognitive Impairment (VCI)
The investigators will conduct a proof-of-concept randomized controlled trial study to provide preliminary evidence of efficacy of a resistance exercise training program for maintaining white matter health and improving cognitive…
- Conditions
- Transient Ischemic Attack, Vascular Cognitive Impairment, Subcortical Vascular Dementia
- Trial name
- NCT02669394
- Testing
- Resistance exercise training, Control: stretching and relaxation program
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of British Columbia
Chronic Subdural Hematoma
Tranexamic Acid Therapy For The Treatment of Subdural Hematomas
This Phase II randomized, placebo-controlled, double-blinded trial is the first step in our endeavor to improve the clinical outcomes of patients with chronic subdural hematomas (cSDH).
- Trial name
- NCT06718751
- Testing
- Tranexamic Acid 650 MG
- Volunteers
- 240 people
- Sponsor
- Baylor College of Medicine
Acute Ischemic Stroke
Study on Hibernation-like Therapy Based on Mechanical Thrombectomy
The goal of this clinical trial is to learn whether chlorpromazine and promethazine（C+P）is safe in Acute Ischemic Stroke（AIS) patients and determine the maximum dosage.
- Trial name
- CHILL-1 (NCT06663631)
- Testing
- chlorpromazine and promethazine, endovascular thrombectomy, rt-PA
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Capital Medical University
Takayasu's Arteritis, Giant Cell Arteritis
Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis
Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are diseases that cause swelling of the arteries in the head, neck, upper body, and arms.
- Trial name
- NCT00556439
- Testing
- Abatacept
- Where
- 10 sites in United States, Canada
- Volunteers
- 97 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Surgical Complications From General Anesthesia, Hypertension
Monitoring Hypertensive Patients's Cerebral Oxygen Saturation
The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.
- Conditions
- Surgical Complications From General Anesthesia, Hypertension, Cerebral Ischemia, Cerebral Anoxia
- Trial name
- MHPCOS (NCT02147275)
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology
Dysphagia
Swallowing Training Combined With Game-based Biofeedback in Post-stroke Dysphagia
The purpose of this study is to determine whether swallowing training combined with game-based biofeedback is effective in the treatment of dysphagia due to stroke.
- Trial name
- NCT01967212
- Testing
- Game-based swallow biofeedback, Swallow training without biofeedback
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Acute Ischemic Stroke
Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stroke With Large Vessel Occlusion
The purpose of this study is to evaluate the safety and efficacy of Human Urinary Kallidinogenase combined with endovascular therapy in acute ischemic stroke (AIS) patients with large vessel occlusion.
- Trial name
- HEAL (NCT06211712)
- Testing
- Experimental: Human Urinary Kallidinogenase
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Intracranial Aneurysm
Study on the Effectiveness and Safety of Coil System for Intracranial Aneurysm Embolization
"Study on the effectiveness and safety of the coil system for the treatment of intracranial aneurysms embolization" was sponsored by Zhuhai Tongqiao Medical Technology Co., Ltd.
- Trial name
- NCT04497181
- Testing
- Coil embolization surgery
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Brain Hemorrhage
Prognostic Analysis of Different Treatment Options for Cerebral Hemorrhage
To analyze the influence of early hematoma morphology on hematoma expansion, optimize the treatment plan for cerebral hemorrhage, and guide the treatment of patients with cerebral hemorrhage in combination with clinical practice.
- Trial name
- NCT05548530
- Testing
- Stereotactic intracranial hematoma puncture, decompressive craniectomy, Neuroendoscopic
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Carotid Artery Stenosis, Carotid Artery Diseases
Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets for Cerebral Protection During Carotid Angioplasty
- Trial name
- NCT06959628
- Testing
- Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Intracranial Aneurysm
INCA: Intracranial Aneurysm Treatment With NeXsys
Prospective, single center first-in-man study of use of device for intracranial aneurysm occlusion
- Trial name
- INCA (NCT02507531)
- Testing
- NeXsys Embolization System
- Where
- Argentina
- Volunteers
- 3 people
- Sponsor
- Cerus Endovascular, Inc.
Stroke
Comparing Perceptual Motor Training and Repetitive Facilitation Exercises on UE in Stroke
The aim of the study is to determine the comparative effects of perceptual motor training and repetitive facilitation exercises on upper limb quality of movement and motor function in Stroke patients.
- Trial name
- NCT06688812
- Testing
- Perceptual Motor Training, Repetitive Facilitation Exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Cardiovascular Diseases, Cerebrovascular Disease
RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)
The clinical efficacy of LDL-lowering therapy have been proven with strong evidences and more emphasized. However, there are also growing concerns that high-intensity statin would be related to increased risk of adverse effects.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Disease, Peripheral Atherosclerotic Disease
- Trial name
- NCT03044665
- Testing
- Rosuvastatin, Rosuvastatin plus ezetimibe
- Where
- South Korea
- Volunteers
- 3,780 people
- Sponsor
- Yonsei University
Brain Injuries, Multiple Sclerosis
Evaluation of an Acceptance and Commitment Therapy Group for Adjustment Difficulties in Neurological Conditions
With an increase of over 38% in neurological related hospital admissions between 2008-13, there are now over 12.5 million cases of individuals with neurological conditions in the UK.
- Conditions
- Brain Injuries, Multiple Sclerosis, Parkinson Disease, Stroke
- Trial name
- NCT02454465
- Testing
- Acceptance and Commitment Therapy group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Hertfordshire
Ischemic Stroke
A Study of Survival and Outcome After Stroke
The objective of this study is to determine the natural history of acute ischemic stroke from large vessel thromboembolism in the brain.
- Trial name
- SOS (NCT01193569)
- Where
- United Kingdom
- Volunteers
- 142 people
- Sponsor
- Penumbra Inc.
Intracranial Hemorrhages
Minimal Invasive Surgical Intracerebral Hemorrhage Removal
This is a feasibility study trial to determine whether hyperacute (≤8 hour) mechanical Minimal Invasive Surgical (MIS) management is feasible and secondarily improves outcome in patients with spontaneous supratentorial…
- Trial name
- HEALME (NCT05138341)
- Testing
- Minimally invasive surgical (MIS) intracranial hemorrhage Evacuation
- Volunteers
- 16 people
- Sponsor
- The Ottawa Hospital
Stroke
Online Neuropilates Classes in Chronic Stroke Patients: A Pilot Randomised Feasibility Study
This study is being undertaken as part of a PhD qualification at ATU Sligo by the principal researcher Eimear Cronin. It will investigate the feasibility, safety and efficacy of a 6 week, online, remotely supervised neuropilates…
- Trial name
- NCT05739422
- Testing
- Neuropilates online exercise class, Online generalised exercise class, Unsupervised home exercise programme
- Where
- Ireland
- Volunteers
- 12 people
- Sponsor
- Institute of Technology, Sligo
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