Clinical trials: Cerebrovascular Diseases
Stroke
Perfusion Enhancement With Respiratory Impedance in Stroke (PERI-Stroke)
This is a non-randomized phase 2 study designed to asses the mean flow velocity (MFV) and cerebral blood flow (CBF) response to non-invasive respiratory impedance.
- Trial name
- PERI-Stroke (NCT03476954)
- Testing
- Respiratory Impedance (RI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Stroke, Upper Extremity Dysfunction
Exoskeleton-assisted Upper Limb Rehabilitation After Stroke
In recent studies, it has been observed that robotic devices make a positive contribution to motor recovery and the activities of daily living.
- Trial name
- NCT04353622
- Testing
- Exoskeleton robot for upper extremity, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Stroke, Sensory Deficits
The Effects of Lower Extremity Sensory Retraining Treatment in Individuals With Post-stroke Sensory Impairment
Background: It is estimated that 50%-85% of individuals post stroke demonstrate sensory deficits. Sensory impairments are often overlooked in the therapeutic setting, although they lead to slower motor recovery.
- Trial name
- NCT01988220
- Testing
- sensory retraining, repeated sensory input
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Yocheved Laufer
Stroke
Brain Activity Changes After Structured Cognitive-motor Exercise for People With Stroke
To assess the effects of a dual-task exercise program on cognitive-motor interference during dual-task walking and the associated changes in brain activity.
- Trial name
- NCT06129227
- Testing
- Dual-task training, Single-task training, Control group
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- The Hong Kong Polytechnic University
Aneurysm Cerebral
Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of…
- Trial name
- CAR (NCT06215105)
- Testing
- Intracranial Aneurysm Devices
- Where
- 5 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Microvention-Terumo, Inc.
Stroke, Cognitive Impairment
The Treatment Effectiveness of Combined tDCs and Neurofeedback (NF) for Patients With Cognitive Deficits After Stroke
This is a double blinded, randomized control trial with a pretest-posttest control and interventional groups design. Both the assessor and participants are blinded to all assessments and evaluations.
- Trial name
- NCT03093142
- Testing
- tDCS & neurofeedback, neurofeedback
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Kowloon Hospital, Hong Kong
Atrial Fibrillation, Stroke
Screening Versus Routine Practice in Detection of Atrial Fibrillation in the Elderly Population of Lieto
The aim of this study is to evaluate the feasibility of patient education on feeling the own pulse irregularity in the elderly population of Lieto. Prevalence of atrial fibrillation (AF) rises with age.
- Trial name
- LietoAF (NCT01721005)
- Testing
- Subject education to pulse palpation
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Turku
Stroke, Postural Balance, Virtual Rehabilitation
Chronicity Dependence of a Balance Training in Adults Post-stroke
The level of stroke chronicity has been proposed as an influential variable related to functional balance. However, little is known about the effect of this variable on the effectiveness and maintenance of gains of physical…
- Trial name
- NCT02673294
- Testing
- balance virtual rehabilitation
- Volunteers
- 47 people
- Sponsor
- Hospitales Nisa
Cerebral Vein Thrombosis
Venous Sinus Thrombosis : Clinical Picture and Outcome
Cerebral venous sinus thrombosis (cvst) is an underdiagnosed neurological condition with variable clinical presentations and variable risk factors CVST is often an underdiagnosed cause of acute or slowly progressive neurological…
- Trial name
- NCT05211102
- Volunteers
- 50 people
- Sponsor
- Assiut University
Ischemic Stroke
Selenium and Ischemic Stroke Outcome
Selenium is a trace element essential to human health.Selenium protection against cellular damage by oxygen radicals is accomplished through selenoproteins.
- Trial name
- NCT02505295
- Testing
- Selenium, normal saline
- Where
- Iran
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Giant Cell Arteritis (GCA)
The VGR GCA Cohort: Ultrasound, Biopsy and Biomarkers - Novel Methods for Diagnosis, Monitoring and Prognosis in Giant Cell Arteritis.
Giant cell arteritis (GCA) is the most common vasculitis in the elderly and is usually treated with long-term corticosteroid therapy. Many patients experience relapses and treatment-related side effects.
- Trial name
- NCT07246577
- Where
- Sweden
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Hypoxic-Ischemic Encephalopathy
The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIE
The goal of this clinical trial is to evaluate the effects of minimal enteral nutrition (MEN) on mesenteric blood flow and oxygenation with Doppler USG and Near Infrared Spectroscopy (NIRS) during therapeutic hypo¬thermia (TH) in…
- Trial name
- NCT06344286
- Testing
- Minimal enteral nutrition, Distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Training and Research Hospital
Acute Brain Injury, Ventilator-Induced Lung Injury
Ventilator Settings on Patients With Acute Brain Injury
The present study is an explorative analysis of the relationship between cerebral blood perfusion and oxygenation and lung mechanical variables at different ventilator settings.
- Conditions
- Acute Brain Injury, Ventilator-Induced Lung Injury, Cerebrovascular Circulation
- Trial name
- NCT03278769
- Testing
- Lung protective ventilator settings
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- University Hospital of North Norway
Stroke
Evaluation of Robotic Arm Rehabilitation in Stroke Patients
The purpose of this study is to compare 2 training programs using robotic exercise devices to supervised arm exercises in stroke patients with chronic stable deficits.
- Trial name
- NCT00333983
- Testing
- Robotic Upper Extremity Neurorehabilitation, Traditional Upper Extremity Exercise Group
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- US Department of Veterans Affairs
First-ever Ischemic Stroke, Cognitive Performance
Post-stroke Cognitive Impairment
Present study aims to track the post-stroke cognitive trajectories and to investigate its inter-individual variability.
- Trial name
- CogStroke (NCT05653141)
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Roza Umarova
Stroke, Ischemic
MUcociliary Clearance IN Stroke
Stroke patients frequently suffer from stroke associated pneumonia. Pathophysiologically speaking, dysphagia and central nervous system (CNS)-injury induced immunosuppression largely contribute to the risk for pneumonia.
- Trial name
- MUCINS (NCT03884166)
- Testing
- bronchoscopy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Cerebrovascular Disorder, Stroke
Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
Background: A stroke occurs when not enough blood reaches the brain. Sometimes stroke causes changes in certain brain matter. This is called white matter hyperintensity (WMH) and can lead to mental decline.
- Conditions
- Cerebrovascular Disorder, Stroke, Aging
- Trial name
- NCT03366129
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Transient Ischemic Attack
Prospective Evaluation of Carotid Free-floating Thrombus
Hardened plaque located in the carotid arteries can cause stroke or transient ischemic attack (TIA). This type of plaque is linked to unstable free-floating thrombi (FFT).
- Trial name
- NCT02405845
- Testing
- Computed Tomographic Angiogram
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Stroke
Validity and Reliability of the Virtual Reality-Based 9-Hole Peg Test in Stroke Patients
The goal of this observational study is to demonstrate diagnostic value of a VR-based 9-hole peg test (9HPT) for the evaluation of manual dexterity in stroke patients.
- Trial name
- NCT06583772
- Testing
- VR-based 9-hole peg test
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara University
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