Clinical trials: Cerebrovascular Diseases
Aphasia, Acquired, Language Disorders
Enhancing Language Function in Aphasia
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain).
- Conditions
- Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
- Trial name
- NCT05443633
- Testing
- individualized speech-language training, standard language intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
ARDS
Cerebrovascular Hemodynamics in Patients With ARDS.
The acute respiratory distress syndrome (ARDS) is a life-threatening disease with functional impairment of the lung. It is characterized by an excessive inflammatory response of lung tissue, capillaries, and blood vessels and is…
- Trial name
- NCT03949738
- Testing
- Near-infrared spectroscopy-based assessement of cerebral autoregulation.
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke, Hemiplegia
Robot-Assisted Stroke Rehabilitation Based on Patient-Therapist Interactions
Our study goal is to assess natural patient-therapist interactions in order to map such human-human activities to robot-human interactions.
- Conditions
- Stroke, Hemiplegia, Healthy
- Trial name
- Baxter (NCT02806843)
- Testing
- Rehab InterCap system and 3D Kinect
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Task-Oriented Upper Limb Training With Focal Vibration in Stroke
This study aims to investigate the effects of task-oriented upper limb training combined with focal vibration on hand function, proprioception, and muscle tone in patients with stroke.
- Trial name
- NCT07558876
- Testing
- Task-oriented upper limb training combined with focal vibration, Active Comparator: Task-Oriented Upper Limb Training Alone
- Where
- 2 sites in South Korea
- Volunteers
- 38 people
- Sponsor
- Jisu Kim
Cerebrovascular Accident
The Effects of Mirror Therapy on Upper Extremity in Stroke Patients
The purpose of this study is to compare treatment efficacy of mirror therapy (MT), mirror therapy combining mesh glove (MG+MT) stimulation, and controlled treatment (CT) in people with stroke.
- Trial name
- NCT01656876
- Testing
- Mirror box training, mesh glove stimulation, conventional intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Hospital
Sinus Thrombosis, Intracranial
Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
Background: Endovascular thrombolysis, with or without mechanical clot removal (ET), may be beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT), who have a poor prognosis despite treatment with…
- Trial name
- TOACT (NCT01204333)
- Testing
- Endovascular thrombolysis, Heparin
- Where
- 15 sites in Canada, China and 4 more
- Volunteers
- 67 people
- Sponsor
- Jan Stam, MD, PhD
Stroke, Atheroscleroses
A Cohort Study on Cardiovascular and Cerebrovascular Outcomes
A standardized tool for grading carotid atherosclerotic plaques-dubbed Carotid Plaque-RADS (Reporting and Data System)-has recently been developed.
- Trial name
- NCT07178015
- Testing
- ultrasound scanning
- Where
- China
- Volunteers
- 855 people
- Sponsor
- Sun Yat-sen University
Cerebrovascular Accident, Hemiparesis
Effects of Strength Training on Upper-Limb Function in Post-Stroke Hemiparesis
Our overall goal is to develop therapeutic interventions to improve upper-limb motor function in hemiparetic persons based on an improved understanding of the mechanisms responsible for its loss and recovery.
- Trial name
- NCT00037908
- Testing
- Strength training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Cerebral Amyloid Angiopathy
Antibiotics Against Amyloid Angiopathy
We will perform a randomized clinical trial with minocycline. Minocycline is an antibiotic of the tetracycline family and known to modulate inflammation, gelatinase activity and angiogenesis, which we know are central mechanisms…
- Trial name
- BATMAN (NCT05680389)
- Testing
- Minocycline
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Chronic Stroke, Non-use of the Paretic Upper Limb
Actimetry Monitoring of the Paretic Upper Limb in Chronic Post Stroke.
After a stroke, 80% of patients continue to have difficulty using their paretic upper limb in activities of daily living (ADL) despite post-stroke rehabilitation practices that aim to promote the use of the paretic upper limb.
- Trial name
- ParUse (NCT05581602)
- Testing
- Wearing bracelets (3-Axis Logging Accelerometer)
- Where
- 2 sites in France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke
Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation
Title: Optimal Delay Time to Initiate Anticoagulation after Ischemic Stroke in Atrial Fibrillation (START): a pragmatic, adaptive randomized clinical trial.
- Trial name
- START (NCT03021928)
- Testing
- Time-To-Treatment Randomization
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Texas at Austin
Cerebral Hemorrhage
Multimodal Monitoring in Patients With Spontaneous Intracerebral Hemorrhage
Spontaneous intracerebral bleeding also known as spontaneous intracerebral hemorrhage (sICH) constitute 10-15 % of all apoplexies.
- Trial name
- NCT02326571
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Christian Kærsmose Friberg
Stroke
Return to Work With Post Stroke Communication Disorders
Approximately a quarter of stroke survivors are of working age, and it is well-known that disabilities caused by stroke can lead to difficulties returning to work.
- Trial name
- ConQueSt (NCT05500144)
- Testing
- Not applicable- no intervention administered
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- NHS Grampian
Cerebral Vasospasm
Non-Significant Risk Study Comparing the Nautilus NeuroWaveTM to Transcranial Doppler as an Aid to Diagnosing Vasospasm
The purpose of the study is to determine the sensitivity, specificity and predictive values of the Jan Medical NeuroWave System in detecting moderate and severe vasospasm in comparison to Trans Cranial Doppler(TCD).
- Trial name
- NCT01595802
- Testing
- Nautilus NeuroWave, Transcranial Doppler (TCD)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Jan Medical, Inc.
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Mild Cognitive Disorder, Alzheimer Disease
Digital Dementia Registry Bavaria (digiDEM Bayern): a Multicentre, Prospective, Longitudinal Register Study Including People With Mild Cognitive Impairment and Dementia as Well as Their Family Caregivers
Around 57 million people worldwide live with dementia, with approximately 10 million new cases diagnosed each year. By the end of 2023, around 1.8 million people were living with dementia in Germany, the majority of whom were…
- Conditions
- Mild Cognitive Disorder, Alzheimer Disease, Vascular Dementia, Dementia in Other Diseases Classified Elsewhere
- Trial name
- digiDEM Bayern (NCT07721701)
- Where
- 12 sites in Germany
- Volunteers
- 5,000 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cerebrovascular Disorders, Brain Tumours
Environmental Pollutants and Neurological Disorders
Environmental pollutants have emerged as a major global health concern, with growing evidence linking exposure to both traditional contaminants such as heavy metals (lead, mercury, cadmium, arsenic) and novel pollutants-including…
- Conditions
- Cerebrovascular Disorders, Brain Tumours, Alzheimer Dementia
- Trial name
- CLEAN (NCT07140601)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Stroke
Rehabilitation Effects on Balance With Kinect for Xbox Virtual Reality Games
Virtual reality balance training has already been used in stroke rehabilitation, and previous studies supported that could improve balance ability.
- Trial name
- NCT02735265
- Testing
- Virtual reality, Standard treatment
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Coronary Disease, Cardiovascular Diseases
Cardiac and Renal Disease Study (CARDS)
To examine the epidemiology of renal disease and its relationship to cardiovascular disease.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident, Heart Failure
- Trial name
- NCT00049907
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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