Clinical trials: Cerebrovascular Diseases
STROKE
Effect of Motor Relearning Programme and Mirror Therapy Along for Improving Hand Function In Patients With Stroke.
Study was conducted Effectiveness of Motor Relearning Programme and Mirror Therapy along with Conventional Physiotherapy treatment for improving Hand Function In Patients with stroke.
- Trial name
- NCT02338557
- Testing
- motor relearning programme, MIRROR THERAPY
- Volunteers
- 12 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Carotid Artery Plaque, Atherosclerosis
IMaging Della PLAcca Carotidea
Background-White matter hyperintensities (WMH), patchy areas of hyperintense signal on T2-weighted or Fluid Attenuated Inversion Recovery sequences on brain magnetic resonance imaging (MRI), are believed to reflect cerebral…
- Conditions
- Carotid Artery Plaque, Atherosclerosis, Ischemic Stroke
- Trial name
- IMPLAC (NCT03333330)
- Testing
- Visipaque 320 and SonoVue
- Volunteers
- 75 people
- Sponsor
- Enrico Ammirati
Alzheimer's Disease, Dementia With Lewy Bodies
Imaging of Brain Amyloid Plaques in the Aging Population
This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in…
- Conditions
- Alzheimer's Disease, Dementia With Lewy Bodies, Frontotemporal Dementia, Vascular Dementia
- Trial name
- NCT00950430
- Testing
- Pittsburgh Compound B (C-11 PiB), F-18 FDG, Tau (18-F-AV-1451)
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Stroke
Clinical Trial of Robot-assisted-gait-training (RAGT) in Stroke Patients
A clinical trial of robot-assisted-gait-training (RAGT) in stroke patients to evaluate its efficacy, safety over conventional gait training.
- Trial name
- Walkbot (NCT02694302)
- Testing
- Walkbot, Conventional physical therapy
- Where
- 2 sites in South Korea
- Volunteers
- 91 people
- Sponsor
- P&S Mechanics Co., Ltd.
Cerebrovascular Disorders, Peripheral Nervous System Diseases
Effectiveness of Controlled-perturbation Gait Training on Gait Rehabilitation and Fear of Falling in Individuals With Gait Impairments
Gait dysfunction often occurs following stroke, neurological or musculoskeletal disease, injury and surgery. One of the consequences of such deficit is an increased risk of fall and injury.
- Conditions
- Cerebrovascular Disorders, Peripheral Nervous System Diseases, Musculoskeletal Diseases, Joint Diseases
- Trial name
- NCT02031757
- Testing
- perturbation training, balance exercises
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Stroke
Effect of Segmental Muscle Vibration on Upper Limb Function in Post Stroke Patients
The aim of this study is to observe and to compare effects of segmental vibration on flexors versus extensor muscle groups on upper limb function in post-stroke patients.
- Trial name
- NCT05356481
- Testing
- segmental muscle vibration
- Where
- 2 sites in Pakistan
- Volunteers
- 57 people
- Sponsor
- Riphah International University
Retinal Artery Occlusion
Long-term Clinical Outcomes After Retinal Artery Occlusion
Retinal artery occlusion (RAO) is a rare but vision-threatening vascular disorder that is commonly caused by embolic events originating from the heart or carotid arteries.
- Trial name
- CVO-RAO (NCT07482228)
- Testing
- retinal artery occlusion
- Where
- South Korea
- Volunteers
- 15,000 people
- Sponsor
- Chonnam National University Hospital
Cerebrovascular Disease
Aerobic Dance Training in Small Vessel Disease
Introduction: Cerebral small vessel disease (SVD) is associated with age-related disabilities including dementia, depression, physical and functional impairment. Chinese are more prone to developing SVD than Caucasians.
- Trial name
- ADTSVD (NCT02730065)
- Testing
- Structured Aerobic Dance Training Group, Stretching plus education
- Where
- 2 sites in Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Peripheral Arterial Disease, Carotid Stenosis
EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs
The purpose of this study is to determine the prevalence and risk factors, at the time of the diagnosis of PAD, for asymptomatic carotid stenosis and abdominal aortic aneurysm.
- Conditions
- Peripheral Arterial Disease, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- EVART (NCT01224600)
- Testing
- patients with newly diagnosed PAD (<1year)
- Where
- 115 sites in Belgium, France
- Volunteers
- 1,056 people
- Sponsor
- Institut de l'Atherothrombose
Atherosclerosis, Cardiovascular Diseases
Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study
To evaluate the relation of retinal microvascular characteristics to subclinical cardiovascular disease, clinical disease, and their risk factors in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease
- Trial name
- MESA-Eye (NCT00041444)
- Volunteers
- 6,176 people
- Sponsor
- University of Wisconsin, Madison
Stroke, Stroke Sequelae
Neural Bases of Post-stroke Emotion Perception Disorders
This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.
- Conditions
- Stroke, Stroke Sequelae, Emotions
- Trial name
- STROKEM (NCT05595005)
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Stroke Not Otherwise Specified
More Steps Towards an Active Life After Stroke - ActForStroke
The main goal of this quasi-experimental study is to prevent the negative consequences of mobility impairments after stroke. These include recurrent strokes, general deconditioning, and overweight on the physical side, and…
- Trial name
- ActForStroke (NCT06715566)
- Testing
- ActForStroke, Standard care
- Where
- 10 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Subarachnoid Hemorrhage, Anxiety
Massage Technique for Pain, Anxiety and Delirium in SAH Patients
This research study seeks to explore the effects of massage techniques on pain and anxiety relief among patients with subarachnoid hemorrhages in the ICU setting in comparison to subarachnoid hemorrhagic patients using standard…
- Conditions
- Subarachnoid Hemorrhage, Anxiety, Pain, Delirium
- Trial name
- NCT01982656
- Testing
- Massage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sara E. Hocker, M.D
Moyamoya Disease
Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya Disease
The purpose of this study is to comprehensively evaluate the risk factors for cognitive decline in patients with moyamoya disease, identify imaging target areas associated with cognitive damage in the brain, and explore the…
- Trial name
- NCT06832839
- Testing
- Revascularization
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute Ischemic, Medium Vessel Occlusion
INTRA-ARTERIAL MeVO TREATMENT (IMP-ACT) Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632
This domain will be conducted as part of ACT-GLOBAL platform trial and will have the nested domain name of IMP-ACT. Acute ischemic stroke (AIS) caused by intracranial arterial occlusion remains a major cause of disability and…
- Trial name
- IMP-ACT (NCT07906275)
- Testing
- Mechanical Endovascular Thrombectomy, Intravenous Thrombolysis, Tenecteplase/Alteplase- depending upon availability at each treating centre
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
Mobility Limitation, Balance Impairment
TIME™ at Home Feasibility Study: Evaluation of a Virtually Delivered, Community-based, Task-oriented Exercise Program
Balance and mobility limitations can lead to increased difficulty with everyday function and increased dependence on caregivers.
- Trial name
- NCT05369741
- Testing
- TIME™ at Home
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Subarachnoid Hemorrhage, Aneurysmal
Mild Hypothermia During Intracranial Aneurysm Clipping
The purpose of this study is to determine whether mild hypothermia causes reduction of vasoconstriction in microcirculation after clipping of aneurysms, and affects the blood flow in small diameter arteries at operating site…
- Trial name
- NCT02544256
- Testing
- Mild hypothermia
- Where
- Czechia
- Sponsor
- University Hospital Hradec Kralove
Stroke, Ischemic Stroke
Safety Study of Post Intravenous tPA Monitoring in Ischemic Stroke
Intravenous (IV) tissue plasminogen activator (tPA) is the only FDA-approved therapy for treatment of acute ischemic stroke. In the United States, IV tPA is typically administered in the Emergency Department (ED) for patients…
- Trial name
- OPTIMIST (NCT02039375)
- Testing
- "Hopkins" post tPA for ischemic stroke monitoring protocol
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University
Ischemic Stroke
Intra-arterial Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke
This trial aims to test that intra-arterial injection of autologous bone marrow mononuclear cells in acute ischemic stroke patients is safe and improves neurological outcomes.
- Trial name
- NCT02178657
- Testing
- Autologous bone marrow mononuclear cell intra-arterial injection
- Where
- 4 sites in Spain
- Volunteers
- 76 people
- Sponsor
- Andalusian Initiative for Advanced Therapies
Ischaemic Stroke
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial
When to start anticoagulation in patients with an acute ischaemic stroke and atrial fibrillation (AF) is a relevant unanswered question in clinical practice.
- Trial name
- ELAN (NCT03148457)
- Testing
- Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
- Where
- 98 sites in Austria, Belgium and 13 more
- Volunteers
- 2,013 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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