Clinical trials: Cerebrovascular Disorders
Horton Disease
Velocimetric Study of Temporal Arteries in Patients With Horton Disease Using Scan-Doppler
The use of ultrasonography in detecting giant cell arteritis ( GCA) is emerging. Currently, temporal biopsy is the gold standard to diagnose GCA but studies have shown the interest to use B mode ultrasonography.
- Trial name
- VELHOR (NCT03360162)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Stroke, Sarcopenia
The Change in Temporal Muscle Thickness in Stroke Patients
This study aims to evaluate the relationship between sarcopenia and functional outcomes with temporal muscle mass change.
- Trial name
- NCT05456646
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bozyaka Training and Research Hospital
Stroke, Post-Stroke Cognitive Impairment (PSCI)
Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment
This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment (PSCI), Cognitive Dysfunction, Virtual Reality Therapy
- Trial name
- NCT07125170
- Testing
- Kinesix XR on Meta Quest 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Intracranial Atherosclerosis ICAS, Hemodynamic
Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis
The goal of this observational study is to learn whether a digital angiography derived fractional flow reserve (DPR) measurement can improve the prediction of stroke risk in adults with symptomatic intracranial atherosclerotic…
- Conditions
- Intracranial Atherosclerosis ICAS, Hemodynamic, Stroke
- Trial name
- CASSISS-DPR (NCT07309705)
- Testing
- Standardized medical therapy targeting vascular risk factors and stroke prevention
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
taVNS Combined With TENS on Motor Function in Stroke
the current study is a Blinded Randomised Controlled Trial investing the effectiveness of Combining Transcutaneous Vagus Nerve Stimulation with Peripheral Nerve Stimulation on Upper Limb Motor Function in People with Stroke
- Trial name
- NCT07425756
- Testing
- transcutaneous auricular vagus nerve stimulation, transcutaneous electrical nerve stimulation, task-oriented training
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Amyotrophic Lateral Sclerosis, Stroke
Telehealth Implementation of Brain-Computer Interface
Determine if Telehealth intervention can allow/empower a caregiver (who is untrained) to effectively implement and utilize a Brain-Computer Interface for communication with a participant who is "Locked in" following progression…
- Trial name
- NCT05951556
- Testing
- Use of BCI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Acute Ischemic Stroke
The Improve Acute Reperfusion Treatment Quality for Ischemic Stroke Through Spatiotemporal Computing Thecnology in China
This study intends to construct the goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model) to promote the…
- Trial name
- IMPROVE-II (NCT06330051)
- Testing
- The goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model)
- Where
- China
- Volunteers
- 2,219 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic, Cerebral Edema
Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct Trial
Early Decompressive Hemicraniectomy for High-Risk Large Ischemic Core Stroke Post-EVTAcute Ischemic Stroke (AIS), particularly Anterior Circulation Large Vessel Occlusion (LVO), is a major cause of global disability and death.
- Trial name
- NCT07118345
- Testing
- Early prophylactic decompressive hemicraniectomy
- Where
- 2 sites in China
- Volunteers
- 380 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Electrical Stimulation and a Dynamic Orthosis for Stroke Recovery
Objective: To explore the effectiveness of a combined neuromuscular electrical stimulation (ES) and dynamic hand orthosis (DHO) regimen used with a small group of persons with chronic stroke in improving ability to perform daily…
- Trial name
- NCT02887872
- Testing
- Electrical stimulation-dynamic hand orthosis
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Acute Ischemic Stroke
The Association of Gut Microbes and Their Metabolites With Post-stroke Depression
In this study, the clinical data of patients with AIS were collected, 16s RNA was used to detect the composition and diversity of intestinal flora, and flow cytometry and mass spectrometry were used to detect intestinal…
- Trial name
- NCT05414227
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
TBI (Traumatic Brain Injury), Stroke
Cognitive Profile of Patients at the Sagol Center for Hyperbaric Medicine and Research
In the investigator's institute there is ongoing treatment of different patients with cognitive deficits using Hyperbaric oxygen therapy (HBOT).
- Conditions
- TBI (Traumatic Brain Injury), Stroke, Fibromyalgia, Aging
- Trial name
- NCT04287283
- Testing
- Hyperbaric Oxygen
- Where
- Israel
- Volunteers
- 2,500 people
- Sponsor
- Assaf-Harofeh Medical Center
Stroke
Saeboflex Dynamic Hand Orthosis for Inpatient Rehabilitation Stroke Patients
The purpose of this study is to determine what the potential utility of the Functional Tone Management (F.T.M) Arm Training Program using the SaeboFlex in an inpatient stroke rehabiliation hospital
- Trial name
- NCT00485641
- Testing
- SaeboFlex Dynamic Hand Orthosis, Saebo F.T.M. Arm Training Program
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Kessler Foundation
Healthy, Hypercholesterolemia
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in lipid metabolism and therapeutic target for hypercholesterolemia and atherosclerotic cardiovascular disease (CVD).
- Conditions
- Healthy, Hypercholesterolemia, Hypertension, Overweight
- Trial name
- NCT06675994
- Testing
- PCSK9 Antibody, PCSK9 Enzyme
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Acute Ischemic Stroke
EmboTrap ® II Revascularization Device (Neuravi) in Acute Ischemic Stroke
The primary aim of Registrap study is to assess the safety and effectiveness of the EmboTrap®II Clot Retriever device (Neuravi) in patients with acute ischemic stroke from large vessel occlusion.
- Trial name
- NCT03601702
- Testing
- Mechanical thrombectomy with EmboTrap ® II Device
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Stroke
Peripheral Nerve Stimulation and Motor Training in Stroke
Cerebrovascular disease is a major cause of disability worldwide. The catastrophic burden of stroke is more dramatic in low- and middle- income countries, and the scarcity of evidence-based rehabilitation interventions represents…
- Trial name
- NCT02658578
- Testing
- PNS
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Neglect
Comparison of Concentric or Eccentric Virtual Reality Training Program in Subacute-stroke Patients With Hemispatial Neglect
The purpose of this study is to compare and analyze how the visual gaze training in the afferent direction and the visual gaze training in the efferent direction using virtual reality affects the improvement of the neglect…
- Trial name
- NCT04651335
- Testing
- afferent virtual reality program, efferent virtual reality program
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Left Atrial Appendage Closure
Left Atrial Appendage Closure With the LAmbre
The study was to retrospectively analyse the efficacy and safety of LAA closure using the LAmbre in our center from April 2014 to November 2015.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Stroke
- Trial name
- NCT03147391
- Testing
- LAA closure with LAmbre
- Volunteers
- 66 people
- Sponsor
- Shanghai 10th People's Hospital
Stroke, Mouth Neoplasms
The Feasibility Study of Dual-Section Nasogastric Tube
The purpose of this studyis to assess the feasibility and safety of novel designed two-piece nasogastric tube.
- Trial name
- NCT01649349
- Testing
- two-piece nasogastric tube
- Volunteers
- 10 people
- Sponsor
- Changhua Christian Hospital