Clinical trials: Cerebrovascular Function
Dream Disorder, Thrombotic Infarction
Biological Function of Dreaming in Dreaming and Non-Dreaming Patients With PCA Infarction
This study is a quasi-experimental between-group design. Using a prospective two-arm controlled exploratory study, data will be collected on an initial assessment of the effects of a specific neurological sample after thrombotic…
- Conditions
- Dream Disorder, Thrombotic Infarction, PCA Infarct
- Trial name
- BFD (NCT04749992)
- Testing
- Polysomnographic examination in sleep laboratory (PSG measurement)
- Where
- 2 sites in Germany
- Volunteers
- 142 people
- Sponsor
- International Psychoanalytic University Berlin
Stroke
Enhanced Treadmill Gait Training With Lower Limb Support After Stroke
This series of single case studies aims to test the feasibility and acceptability of an enhanced treadmill system for the recovery of gait function in stroke survivors.
- Trial name
- ENTRES (NCT03348215)
- Testing
- Enhanced Treadmill Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Strathclyde
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Stroke, Acute, Stroke, Ischemic
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)
The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Subacute, Stroke Hemorrhagic
- Trial name
- EarlyExo (NCT06107010)
- Testing
- Use of the Atalante exoskeleton
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- Wandercraft
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stroke
Effect of Sensorimotor Training Versus Dual-task Training
The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients.
- Trial name
- NCT07628374
- Testing
- Sensorimotor Training, Dual-Task Training, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Hemiplegia, Stroke
Effects of Wearable Vibratory Devices on Arm Function in Subacute Stroke Patients
Hemiplegia, or paralysis of one side of the body, often results from stroke and severely limits arm function. Standard physiotherapy helps, but recovery is often slow.
- Trial name
- WEVIB-HEMI (NCT07641790)
- Testing
- Wearable Focal Muscle Vibrator
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Stroke
rTMS and Robotic Gait Training in Patients With Stroke
Patients with stroke have demonstrated abnormal muscle tone and postural control ability which affect their ambulation, activity of daily living and confident.
- Trial name
- NCT03817385
- Testing
- repetitive TMS, robotic GT
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- Changhua Christian Hospital
Strokes Thrombotic
Efficacy of the Theta Burst Stimulation and Functional Electrical Stimulation in Stroke Rehabilitation
Approximately 50% of patients have persistent motor disability following stroke. Current treatment approaches with conventional physiotherapy have limited efficacy.
- Trial name
- NCT03555474
- Testing
- Theta burst stimulation, Functional Electrical Stimulation, Physiotherapy
- Volunteers
- 60 people
- Sponsor
- Sree Chitra Tirunal Institute for Medical Sciences & Technology
Fabry Disease
A Study of Renal Function in Treatment-naïve, Young Male Patients With Fabry Disease
No investigational drug will be administered in this study for the treatment of Fabry disease. This will be a multicenter, multinational, non-treatment, cross-sectional study of young male patients with Fabry disease who have not…
- Trial name
- NCT01839526
- Testing
- Iohexol
- Where
- 22 sites in United States, Argentina and 12 more
- Volunteers
- 39 people
- Sponsor
- Genzyme, a Sanofi Company
Stroke, Hemiplegia
Virtual Reality-Based Mirror Therapy and FES-Cycling in Stroke Rehabilitation
This randomized controlled, assessor-blinded study aimed to compare the effects of virtual reality-based mirror therapy (VRBMT) and functional electrical stimulation-assisted cycling (FES-cycling) when combined with conventional…
- Conditions
- Stroke, Hemiplegia, Upper Extremity Impairments
- Trial name
- NCT07666308
- Testing
- Conventional Rehabilitation, Virtual Reality-Based Mirror Therapy, Functional Electrical Stimulation-Assisted Cycling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke
Noninvasive Vagal Nerve Stimulation for Arm Recovery After Stroke
This study will find out whether electrical stimulation of a nerve called the "vagus" nerve is acceptable for patients undergoing physiotherapy for arm weakness after a stroke.
- Trial name
- NCT03170791
- Testing
- vagal nerve stimulation intervention
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cardiovascular Diseases, Stroke Sequelae
Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility
Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity…
- Trial name
- NCT07420595
- Testing
- Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks)., Full 12 weeks CGT, progressing complexity and demands.
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Iqra National University
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Effects of Mental Imagery Training Combined With Task Oriented Training by EMG-Driven Soft Robotic Hand Stroke in Stroke
This randomized controlled trial is to determine the effects of robotic hand training in improving upper limb motor function and coordination with and without mental imagery training in chronic stroke patients
- Trial name
- NCT07629011
- Testing
- Mental imagery training combined with Robotic hand training, Robotic hand training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Stroke
Prognostic Value for Predicting Outcome Using Functional Near-infrared Spectroscopy in Stroke Rehabilitation
To investigate the prognostic value of Functional Near-Infrared Spectroscopy (fNIRS) in stroke rehabilitation with serial measurements.
- Trial name
- NCT04288414
- Testing
- functional near-infrared spectroscopy
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Transcranial Direct Current Stimulation
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Upper extremity motor impairment is one of the major sequelae of stroke, resulting in limitation of activities of daily livings.
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Functional Near Infrared Spectroscopy
- Trial name
- NCT04101695
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
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