Clinical trials: Cerebrovascular Stroke
Atrial Fibrillation, Left Atrial Appendage
AMPLATZER Cardiac Plug (ACP) Latin American Post Market Observational
The ACP device will be clinically evaluated through a prospective, open-label, nonrandomized, multi-center post market clinical study.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage, Stroke
- Trial name
- ACP LA (NCT01962051)
- Testing
- Amplatzer Cardiac Plug
- Sponsor
- Abbott Medical Devices
Stroke, Ischemic, Cognitive Decline
Post-stroke Immunological Changes in Young Stroke Patients
In the present study, the investigators aim to elucidate the role of T-cells on cognitive decline in younger stroke patients, using repeated cognitive testing, brain imaging, and immunological analyses in the first 6 month after…
- Trial name
- NCT03725137
- Testing
- Analysis of T-lymphocytes
- Volunteers
- 77 people
- Sponsor
- University Medicine Greifswald
Aphasia, Acquired
PCT for Speech, Language, and Cognitive Intervention in Stroke Patients
Given the evolving uses of technology in rehabilitation, the investigators aimed to measure the change in aphasia severity using PCT App, a digital therapeutic adapted from Constant Therapy (CT), a dynamic, personalized therapy…
- Trial name
- NCT04488029
- Testing
- PCT, Workbooks
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Learning Corp
Stroke, Acute
The Temporal Cellular Landscape of the Adaptive Immune System in Patients With Acute Stroke
Despite novel acute therapies the global burden of stroke remains high worldwide. Targeting the immune response after stroke has the potential to improve recovery in all stroke patients.
- Trial name
- TAPAS (NCT04852445)
- Where
- Netherlands
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ischemic Stroke
Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China
The SAMMPRIS suggested that aggressive treatment was superior to intravascular stenting in patients with severe symptomatic intracranial atherosclerotic stenosis (ICAS) due to high complication rate in patients in stenting group.
- Trial name
- NCT01968122
- Testing
- intravascular stent therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongrong Miao
Stroke, Upper Extremity Paresis
Cortical Enhancement of Posture, Movement Planning, and Execution of Upright Reaching Following Stroke
Stroke is the leading cause of disability and diminished quality of living that frequently includes impairments of postural control and upper extremity (UE) function.
- Trial name
- NCT04308629
- Testing
- Transcranial direct current stimulation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stroke, Hand
Comparative Effects of Sensorimotor Interventions on Hand Performance With Stroke
This randomized controlled trial investigated the comparative effects of sensory, motor, and combined sensorimotor interventions on hand motor function and behavioral performance in patients with stroke.
- Trial name
- NCT07590245
- Testing
- Sensory and Motor Exercise Group, The Sensory Exercise Group, The Motor Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Atlas University
Aphasia, Stroke
Adaptive Trial Scheduling in Naming Treatment for Aphasia
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life.
- Trial name
- NCT05653466
- Testing
- Adaptive Spacing Condition, High-Item Non-Adaptive Spacing Condition, Low-Item Non-Adaptive Spacing Condition
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh
Brain Ischemia With Non-valvular Atrial Fibrillation, Transient Ischemic Attack With Non-valvular Atrial Fibrillation
Prospective Record Of the Use of Dabigatran in Patients With Acute Stroke or TIA
The multi-center, prospective PRODAST study is investigating patients with non-valvular atrial fibrillation (AF) who experienced an ischemic stroke or a transient ischemic attack (TIA) recently (≤ 1 week) both with and without…
- Trial name
- PRODAST (NCT02507856)
- Where
- 90 sites in Germany
- Volunteers
- 10,044 people
- Sponsor
- University Hospital, Essen
Stroke
Focal Muscle Vibration and tDCS on Motor Recovery in Stroke
Although tDCS and FV have shown some benefit as stand-alone treatment, researcher suggest that combining intervention with complementary mechanism can lead to additive or synergistic benefits which might yield more significant…
- Trial name
- NCT06893653
- Testing
- Focal muscle vibration, tDCS, Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Atrial Fibrillation
Improving Stroke Prevention Therapy for Patients With Atrial Fibrillation in Primary Care
The objective of this project is to increase the proportion of patients with AF that receive adequate stroke prevention therapy. Over half of patients with AF who suffer strokes are permanently disabled.
- Trial name
- NCT01927445
- Testing
- quality improvement toolkit
- Where
- Canada
- Volunteers
- 5,000 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Stroke
Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke
Stroke survivors often experience impaired neuromechanical control that limits walking speed and quality, particularly due to deficits in paretic propulsion.
- Trial name
- NCT07218094
- Testing
- Walking with robotic ankle assistance
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Stroke
Telerehabilitation In The Home After Stroke
The purpose of this research study is to evaluate whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compared to usual care alone.
- Trial name
- TR-2 (NCT06682429)
- Testing
- Telerehabilitation
- Where
- 27 sites in United States
- Volunteers
- 202 people
- Sponsor
- University of California, Los Angeles
Stroke
Effects of Upper Extremity Rehabilitation Robot and Transcranial Direct Current Stimulation in Subacute Stroke
Comparison of real transcranial direct current stimulation (tDCS) and sham tDCS combined with robot training for upper extremity rehabilitation.
- Trial name
- NCT04054102
- Testing
- Robot and tDCS on-line
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Coronary Artery Disease, Cardiovascular Mortality
the Change of Cholesterol Efflux Capacity and Coronary Artery Disease in Real Clinical Practice
The purpose of this study is to investigate the change of cholesterol efflux capacity in patients with coronary artery disease treated with secondary prevention drugs, and the correlation with the prognosis.
- Conditions
- Coronary Artery Disease, Cardiovascular Mortality, Myocardial Infarction, Stroke
- Trial name
- NCT03389529
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lu'an Municipal Hospital
Endovascular Thrombectomy, Large Vessel Occlusion
Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions (TRACK-LVO Late)
The objective of this study is to create a comprehensive, multi-center, TRACK-LVO registry-linked cohort of consecutive patients with acute ischemic stroke (AIS) caused by large vessel occlusions (LVO) and presenting to each…
- Conditions
- Endovascular Thrombectomy, Large Vessel Occlusion, Acute Ischemic Stroke
- Trial name
- TRACK-LVO Late (NCT06200753)
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Huanhu Hospital
Stroke, Stroke, Acute
Looking Glass: Bimanual Balanced Reaching With Visual Biofeedback
The goal of this research study is to increase understanding of error augmentation by applying it to visual feedback during motion tracking with a Leap Motion device - a recently developed optical hand tracking tool - and the…
- Conditions
- Stroke, Stroke, Acute, Healthy
- Trial name
- NCT03300141
- Testing
- Veridical Visual Feedback, Augmented Visual Feedback, Healthy Comparative Reaching Task
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Type 2 Diabetes Mellitus (T2DM), Stroke
WhatsApp-Based Education Program for Stroke Patients
Stroke is one of the leading causes of death and disability worldwide, with type 2 diabetes mellitus (T2DM) being a major risk factor that doubles the risk of ischemic stroke.
- Trial name
- WEPS-P (NCT07207694)
- Testing
- WhatsApp-based education group, Active Comparator: Routine Education
- Volunteers
- 84 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Stroke
Influence of Kinesio Taping® in Paretic Tibialis Anterior Muscle During Patient Gait and Balance After Stroke
A pilot study was conducted, randomized, triple-blind study with allocation concealment. Which consisted in the application of KT in the anterior tibial muscle for 24 hours.
- Trial name
- NCT02608294
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco