Clinical trials: Cervical Dilation
Abortion, Induced, Pain Management
Intrauterine Lidocaine for Laminaria
This is a study to investigate whether instilling a small amount of liquid lidocaine into the uterus will decrease pain felt by women during laminaria insertions done for cervical dilation prior to second trimester abortion.
- Trial name
- NCT01541293
- Testing
- Lidocaine, Normal Saline
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Subglottic Stenosis (SGS)
Coblation Assisted Dilatation Versus Modified Maddern Procedure in Subglottic and Cervical Tracheal Stenosis
This study compares the effectiveness of Coblation-assisted endoscopic airway dilatation with the modified Maddern procedure-which involves endoscopic excision of scar tissue followed by buccal mucosal grafting-in patients with…
- Trial name
- NCT07303673
- Testing
- Coblation-assisted dilatation, Modified Maddern procedure
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Dysmenorrhea Primary
The Effect of Cervical Dilatation on Primary Dysmenorrhea
Primary dysmenorrhea (PD) is defined as recurrent, crampy pain occurring with menses in the absence of identifiable pelvic pathology.
- Trial name
- NCT04682262
- Testing
- Cervical dilatation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cervical Dilation, Labor Pain
DilaCheck Cervical Dilation Measurement Trial
Trial to compare the interexaminer agreement between two cervical dilation examinations conducted by Labor and Delivery physicians when using standard methods versus DilaCheck device.
- Conditions
- Cervical Dilation, Labor Pain, Labor Fast, Labor; Irregular
- Trial name
- NCT03440723
- Testing
- DilaCheck, Cervical dilation examination
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Elm Tree Medical Inc.
Second Trimester Abortions
Comparing Misoprostol Alone to Dilapan With Misoprostol and Comparing Buccal to Vaginal Misoprostol
This randomized controlled trial will use a 2 by 2 factorial design to assess methods of cervical preparation prior to Dilation and Evacuations (D\&Es) at 14 0/7 to 19 6/7 weeks gestational age.
- Trial name
- NCT02363556
- Testing
- Misoprostol administered vaginally, Misoprostol administered buccally, Misoprostol administered vaginally with Dilapan
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Termination of Pregnancy
Ulipristal Acetate for Cervical Preparation
This is a prospective cohort study exploring a broadened use of ulipristal acetate as a cervical preparation agent for second trimester surgical abortion.
- Trial name
- U-Prep (NCT03802149)
- Testing
- Ulipristal Acetate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Prolonged First Stage of Labor, Failure of Cervical Dilation as Antepartum Condition
Drotaverine to Shorten the Length of Labor
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being, and for the providers of the birth services.
- Conditions
- Prolonged First Stage of Labor, Failure of Cervical Dilation as Antepartum Condition, Labor Pain, Mild Birth Asphyxia, APGAR 4-7
- Trial name
- NCT01639027
- Testing
- Drotaverine
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Ain Shams Maternity Hospital
Pain Management
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation
This study evaluates the use of Transcutaneous Electrical Nerve Stimulation (TENS) as a method of pain control during osmotic dilator insertion prior to dilation and evacuation.
- Trial name
- NCT03868787
- Testing
- TENS
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ashley Turner, MD
Dilation and Evacuation
Cervical Ripening Balloons for Same-Day Cervical Prep
The goal of this clinical trial is to learn if a cervical ripening balloon (Foley balloon) works to prepare the cervix before same-day outpatient dilation and evacuation (D\&E).
- Trial name
- CRB (NCT06964373)
- Testing
- Cervical Ripening Balloon, Osmotic Dilators
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of New Mexico
Miscarriage in First Trimester
Misoprostol 400 µg Versus 200 µg for Cervical Ripening in 1st Trimester Miscarriage
Local current protocol for cervical ripening in 1st trimester miscarriage recommends 400 µg of misoprostol intravaginally 3 hours before uterine evacuation. This regime has been recommended by some international guidelines .
- Trial name
- MISO200 (NCT02957305)
- Testing
- Misoprostol 400mcg Tab, Misoprostol 200mcg Tab
- Where
- Brazil
- Volunteers
- 211 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Operative Pain
Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain
Caesarean section is a common method of delivery in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique.
- Trial name
- NCT03513237
- Testing
- Cervical dilation
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor Analgesia, Labor Pain
Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late Labor
Oxytocin is a key hormone that regulates uterine contractions during labor. Dural Puncture Epidural Analgesia (DPEA) is a modern technique for labor pain relief that provides faster onset and more reliable analgesia than standard…
- Conditions
- Labor Analgesia, Labor Pain, Oxytocin
- Trial name
- DPEA-OXY (NCT07873814)
- Testing
- Dural Puncture Epidural Analgesia (DPEA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha
Cervical Dilation, Induction of Labor
Ultrasound Assessment of DILAPAN-S
The goal of this observational prospective study is to assess the change in Dilapan-S rod diameters using transvaginal ultrasound over a period of 12 hours in term women undergoing induction of labor.
- Conditions
- Cervical Dilation, Induction of Labor, Ultrasound Evaluation
- Trial name
- NCT04529837
- Testing
- Gauze, No gauze
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Intrauterine Polyp, Intrauterine Synechiae
Study on the Effective Dose and Safety of Esketamine in Hysteroscopic Surgery Under Monitored Anesthesia Care
Cervical dilation-induced somatic responses remain a critical challenge in ambulatory hysteroscopic surgery. Esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, exhibits unique analgesic and sedative properties that…
- Trial name
- NCT07034963
- Testing
- Determine the ED50 and ED95 of esketamine, Intravenous the dose of esketamine ED95, Intravenous remifentanil 1μg∙kg-1
- Where
- China
- Volunteers
- 95 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Cervical Dilatations
Clinical Study on "Pain Control of Cervical Dilation by Lidocaine Solution Injected Into a Disposable Cervical Dilator"
This study is a multicenter, randomized (each group was assigned 1:1), double-blind controlled trial. This study aims to investigate if lidocaine injection into the single-use micro-non-invasive injection cervical dilator (short…
- Trial name
- NCT05955768
- Testing
- Disposable cervical dilator stick combined with lidocaine hydrochloride injection, Disposable cervical dilator stick combined with normal saline injection
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Labor Dystocia
Anticholinergics for Cervical Edema in Labor
The purpose of this study is to is to determine the clinical effectiveness of a single dose of intravenous (IV) medication for the prevention of labor arrest and cesarean delivery in primiparous women undergoing trial of labor.
- Trial name
- ACCEL (NCT06702670)
- Testing
- Treatment with Diphenhydramine, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Assessment, Self, Simulation-Based Education
Brief Title: Portable 3D Visual Material-Supported Simulation Training for Cervical Dilation Assessment
This randomized controlled trial aimed to evaluate the effectiveness of simulation-based education supported by a portable and mobile three-dimensional (3D) visual material on university students' knowledge of cervical dilation…
- Trial name
- NCT07705503
- Testing
- Portable 3D Visual Material-Supported Simulation Training, Standard Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Marmara University