Clinical trials: Cervical Fusion
Anterior Spinal Artery Compression Syndromes, Cervical Region
Effect of Placing the Endotracheal Tube Beyond Cervical C7 Level in Anterior Cervical Decompression and Fusion Surgery
Endotracheal intubation is performed to secure the patient's airway during general anaesthesia undergoing surgery. The procedure involves placing a tube known as endotracheal tube (ETT) mouth into the trachea.
- Trial name
- NCT06473077
- Testing
- ETT beyond C7 level
- Where
- Malaysia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Intervertebral Disc Degeneration
Adjacent Segment Mechanics in Cervical Arthrodesis Patients
This study aims to determine to what extent patient-specific factors, iatrogenic factors, and biomechanical factors influence cervical spine mechanics after single-level and two-level arthrodesis.
- Trial name
- NCT03028402
- Testing
- C5-C6 arthrodesis
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dysphagia
Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative…
- Trial name
- NCT03677310
- Testing
- 3% Sodium Chloride, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Anterior Cervical Pain
The Effect of the Transection of the Omohyoid in the Incidence of Dysphagia in Patients
The investigators believe that the transection of the omohyoid during an anterior cervical discectomy and fusion decreases the incidence of dysphagia in patients who undergo this procedure when compared to patients who do not…
- Trial name
- NCT06482632
- Testing
- Discectomy of Omohyoid, Control group no discectomy of Omohyoid
- Where
- Puerto Rico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Cervical Disc Degenerative Disorder
Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease
The purpose of the study is to evaluate the safety and effectiveness of the NeoDisc compared to anterior cervical discectomy and fusion (ACDF) for the treatment of single-level cervical disc disease, by demonstrating non-inferior…
- Trial name
- NeoDisc™ (NCT00478088)
- Testing
- NeoDisc, Instrumented Anterior Cervical Discectomy and Fusion (ACDF)
- Where
- 22 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- NuVasive
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Degenerative Disc Disease
Investigation of DEXA-C Anterior Cervical Interbody System
FDA Cleared interbody product for the cervical spine, designed to match a patients DEXA scan for increase in fusion rate.
- Trial name
- DEXA-C (NCT05883436)
- Testing
- DEXA-C Cervical Interbody System
- Where
- 4 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Aurora Spine and Pain
Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery.
- Trial name
- NCT05019222
- Testing
- Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Cervical Disc Disease
A Clinical Registry to Track the Real World Use of the Saber-C® Cervical Fusion Device
The objective of this registry study is to collect radiographic and clinical outcome measures to determine the effectiveness of the Saber-C device.
- Trial name
- NCT06240221
- Testing
- Elevation Spine Saber-C System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Research Source
Anesthesia
Dual-loop Target Controlled Infusion for Coadministration of Propofol and Remifentanil Guided by Narcotrend Index
To investigate the application of closed target-controlled infusion(TCI) of propofol and remifentanil guided by Narcotrend index in the anterior cervical decompression and fusion with internal fixation surgery.
- Trial name
- NCT02890186
- Testing
- Narcotrend, experience
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Dysphagia, Dysphonia
The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF
This study is to assess the efficacy of intra-operative intravenous non-steroidal anti-inflammatory drug (Ketorolac) versus intravenous (dexamethasone) administration on dysphagia and dysphonia after anterior cervical discectomy…
- Trial name
- NCT04650893
- Testing
- Intravenous Ketorolac, Intravenous Dexamethasone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dysphagia, Dysphonia
Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion
Our double-blinded, randomized control trial will assess the effect of nebulized racemic epinephrine inpatients undergoing anterior cervical discectomy and fusion (ACDF) procedures.
- Conditions
- Dysphagia, Dysphonia, Postoperative Pain
- Trial name
- NCT02724761
- Testing
- Racemic Epinephrine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Andrew Chung
Symptomatic Cervical Disc Disease
Novum Vitrium® Cervical Cage in Anterior Cervical Discectomy and Fusion
A prospective, multicenter, randomized, concurrently controlled, noninferiority clinical trial to compare the safety and effectiveness of instrumented Bio2 Vitrium Cervical Interbody Device in anterior cervical discectomy and…
- Trial name
- NCT03828136
- Testing
- Novum Vitrium® Cervical Interbody Device, Allograft Ring or Block
- Where
- 7 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bio2 Technologies
Spine Fusion, Spine Surgery
Fusion Status After ACDF
Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF).
- Trial name
- NCT05986006
- Testing
- Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft, Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Cervical Degenerative Disc Disease
Dynamic Cervical Implant (DCI) Versus Anterior Cervical Discectomy And Fusion(ACDF) For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD): An RCT
TO Compare The Clinical And Radiographic Outcomes of DCI VS ACDF For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD)
- Trial name
- NCT05522010
- Testing
- Cervical spine surgery
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University