Clinical trials: Cervical Ripening
Cervical Ripening, Induction of Labor
Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Study Purpose: The purpose of this study is to determine the optimal method for induction of labor in multiparous women who present with an unfavorable cervix.
- Conditions
- Cervical Ripening, Induction of Labor, Multiparity
- Trial name
- NCT03138252
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cervical Ripening
Intravaginal Misoprostol Versus Dinoprostone Before Diagnostik Hysteroscopy
Comparison of intravaginal misoprostol and dinoprostol for the purpose of cervical ripening before diagnostic hysteroscopy in the women at the reproductive age:RANDOMİSED,CONTROLLED PROSPECTİVE TRİAL Objective.
- Trial name
- NCT01620814
- Testing
- Dinoprostone, misoprostol, control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Induction of Labor Affected Fetus / Newborn
Cervical Ripening With a Double-lumen Balloon Catheter for Six Versus Twelve Hours
The Foley catheter is a safe, effective method for cervical ripening. Limited data exists to indicate ideal time of placement for optimal cervical ripening prior to induction.
- Trial name
- NCT03086967
- Testing
- Double-lumen balloon catheter
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Wake Forest University Health Sciences
Induction of Labor Affected Fetus / Newborn, Rupture of Membranes Prior to Onset of Labor
Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes
The study aims to evaluate and assess the effectiveness and safety of vaginal administration of isosorbide mono nitrate (IMN) to induce cervical ripening and shorten the interval time between induction and delivery in women…
- Trial name
- NCT03665779
- Testing
- isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- ahmed nagy shaker ramadan
Cervical Ripening
A Randomised Trial Investigating the Efficacy and Safety of a Vaginal Insert in Pregnant Women at Term
To demonstrate the efficacy of dinoprostone vaginal insert (DVI) for cervical ripening success (either bishop score (BS) ≥7 or vaginal delivery) within 12 hours of vaginal insert administration
- Trial name
- NCT03067727
- Testing
- Dinoprostone
- Where
- 20 sites in Japan
- Volunteers
- 114 people
- Sponsor
- Ferring Pharmaceuticals
Cervical Ripening
Cervical Ripening Balloon Compared With Vaginal Misoprostol for Cervical Ripening in Obese Woman at Term
Cervical ripening balloon compared with vaginal misoprostol for cervical ripening in obese woman at term
- Trial name
- NCT07685756
- Testing
- Cervical folleys, Misoprostol
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- HUDDA Ahmad
Cervical Ripening, Labor Induction
Double Balloon Catheter Versus Dinoprostone Vaginal Insert for Cervical Ripening.
To compare the efficacy of transcervical double balloon catheters versus controlled release dinoprostone vaginal inserts for pre-induction cervical ripening in term women with unfavourable cervices.
- Trial name
- NCT01170819
- Testing
- Double balloon catheter, Dinoprostone 10 mg controlled-release vaginal insert
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Università degli Studi dell'Insubria
Labour,Induced
Oral Misoprostol Solution in Labor Induction
This study compares safety and efficacy between repetitive hourly dose of oral misoprostol and two hourly dose oral regimens for cervical ripening and labor induction.
- Trial name
- NCT03927807
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor Induction
Dinoprostone Vaginal Insert Versus Double Balloon Catheter for Preinduction Cervical Ripening
Effıcacy of dinoprostone vaginal insert versus double- balloon catheter among women in the induction of labor
- Trial name
- NCT03016442
- Testing
- Cook Double Balloon Catheter, Dinoprostone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy
Labour Induction With Misoprostol, Dinoprostone and Bard Catheter
This is a randomised study aimed at comparing the currently most frequently used prostaglandin dinoprostone to two other methods, the cheaper and perhaps more effective prostaglandin misoprostol and a transcervical catheter.
- Trial name
- LI (NCT00602095)
- Testing
- misoprostol, dinoprostone, Bard Catheter (balloon catheter)
- Volunteers
- 592 people
- Sponsor
- Karolinska University Hospital
Induction of Labor Affected Fetus / Newborn
Early Versus Late Amniotomy Following EAB Cervical Ripening
The objective of this study is to investigate the course of labor in early versus late amniotomy following balloon cervical ripening in women undergoing term induction of labor stratified by parity.
- Trial name
- NCT04216628
- Testing
- Amniotomy
- Where
- Israel
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Cervical Ripening, Induction of Labor
Pharmacokinetic (PK) Study of the 200 Microgram (mcg) Misoprostol Vaginal Insert (MVI 200) in Women at Term Gestation (The MVI-PK Study)
The purpose of this study is to determine the pharmacokinetics (PK) of misoprostol acid for the MVI 200 in women requiring cervical ripening and induction of labor.
- Trial name
- NCT01283022
- Testing
- MVI 200
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ferring Pharmaceuticals
Pregnancy Complications
Semi-permanent Acupuncture Effect on Cervical Ripening
Cervical ripening is a medical treatment that can cause physical or emotional discomfort in pregnant women and is not without risks.
- Trial name
- NCT06357962
- Testing
- Semi-permanent acupuncture
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Induction of Labor Affected Fetus / Newborn
Tension Versus no Tension With Foley Bulb Induction
To compare the application of tension versus no tension in Foley transcervical catheters for pre-induction cervical ripening.
- Trial name
- NCT03588585
- Testing
- Tension, NO TENSION
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hawaii Pacific Health
Membrane Stripping, Cervical Ripening
The SWEEP Trial: a Randomized Controlled Trial
The purpose of this clinical trial is to determine whether serial membrane sweeping at term is more effective than no membrane sweeping in promoting spontaneous onset of labor.
- Conditions
- Membrane Stripping, Cervical Ripening, Memrane Sweeping
- Trial name
- NCT07043088
- Testing
- Membrane sweeping
- Where
- 2 sites in Denmark
- Volunteers
- 1,536 people
- Sponsor
- University of Aarhus
Cervical Ripening
Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
Ninety healthy pregnant women candidate for surgical evacuation after confirming 1st trimester pregnancy loss were enrolled in the study.
- Trial name
- NCT02738177
- Testing
- Misoprostol, Isosorbide-5-mononitrate, misoprostol and Isosorbide-5-mononitrate
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Induction of Labor Affected Fetus / Newborn
Cervical Ripening in Obese Women: Efficacy of 25 mcg Versus 50 mcg of Misoprostol
This is a prospective clinical trial to determine if 50 mcg versus 25 mcg po every four hours of misoprostol has improved efficacy and similar safety in obese women undergoing cesarean section.
- Trial name
- NCT03748147
- Testing
- Misoprostol
- Volunteers
- 300 people
- Sponsor
- University of Cincinnati
Induction of Labor
Comparing Outpatient and Inpatient Use of a Cervical Balloon for Starting Labor in Low-Risk Pregnancies.
Why was this study done? About 20-30% of pregnancies involve labor being started artificially, known as induction. One way to do this is with a balloon catheter placed in the cervix, which helps prepare the body for labor.
- Trial name
- Cook (NCT06983535)
- Testing
- cervical balloon catheter
- Where
- 4 sites in Belgium
- Volunteers
- 358 people
- Sponsor
- Ziekenhuis Oost-Limburg
Delivery
Comparing the Efficiency of Cervical Ripening BALLoon (Cook) to the DINOprostone (Propess) for the Cervical Maturation in Case of Unfavorable Cervix (Bishop <6) in the Population of Obese Pregnant Women (BMI >= 30 kg/m²)
At the moment in France, one delivery on four is induced for a medical indication. In this context, the practitioners are exposed to an additional difficulty when the clinical examination of the patient reveals a unfavorable…
- Trial name
- BALLODINO (NCT02649920)
- Testing
- Cervical ripening balloon, Dinoprostone
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha