Clinical trials: Cervical Ripening
Cervical Ripening
Misoprostol For Nulliparous Women Before Hysteroscopy
To compare the impact of 400-microgram self-administered vaginal versus self-administered oral misoprostol at home on preoperative cervical ripening in nulliparous women prior to outpatient hysteroscopy.
- Trial name
- NCT01156948
- Testing
- misoprostol, oral misoprostol
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Induced Vaginal Delivery
Tension Versus Tension- Free Foley Balloon for Cervical Ripening
Foley balloons are commonly used as a mechanical method of cervical ripening for induction of labor. Foley balloons may be placed either under tension or without tension (tension-free).
- Trial name
- NCT05404776
- Testing
- Placement of Foley balloon for cervical ripening with tension., Placement of Foley balloon for cervical ripening without tension.
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Labor Induction
Observatory on Artificial Labour-induction Methods and Measuring Immediate Postpartum Maternal Satisfaction
Our hypothesis is that there is one sequence of labour-induction that leads to a better experience of childbirth than others. This is based on the following underlying theories : Maternal satisfaction depends on the number of…
- Trial name
- SATISFACC (NCT04075630)
- Where
- 2 sites in France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Induction of Labor, Cervical Ripening
Comparison of Vaginal Misoprostol Plus Supracervical Balloon Versus Vaginal Misoprostol Alone for Induction of Labor
Demonstrate that with concomitant and synchronous use of supracervical balloon and vaginal misoprostol for induction of labour, vaginal delivery is achieved in less time compared with vaginal misoprostol alone.
- Conditions
- Induction of Labor, Cervical Ripening, Pregnancy
- Trial name
- NCT02762942
- Testing
- Misoprostol, Foley catheter
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari de Terrassa
Induction of Labor
Cervical Foley Plus Vaginal Misoprostol for Labor Induction
The purpose of this study is to compare the efficacy of the combination of the supracervical foley bulb and vaginal misoprostol to vaginal misoprostol alone for labor induction.
- Trial name
- NCT01279343
- Testing
- Foley bulb
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Induction of Labor Affected Fetus / Newborn
Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor
The study aims to evaluate and assess the effectiveness and safety of vaginal administration of isosorbide mono nitrate (IMN) to induce cervical ripening and shorten the interval time between induction and delivery in women…
- Trial name
- NCT03544606
- Testing
- isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- ahmed nagy shaker ramadan
Cervical Ripening, Induction of Labor
Misoprostol Vaginal Insert (MVI) 100, 150, 200 mcg for Cervical Ripening and Induction of Labor
The purpose of this study is to assess the efficacy and safety of the 100, 150 and 200 mcg Misoprostol Vaginal Insert (MVI 100, MVI 150 and MVI 200) for women requiring cervical ripening and induction of labor.
- Trial name
- NCT00828711
- Testing
- MVI 100, MVI 150, MVI 200
- Where
- 11 sites in United States
- Volunteers
- 374 people
- Sponsor
- Ferring Pharmaceuticals
Premature Rupture of Membrane, Unfavorable Cervix
Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices
This study is designed to determine if an intracervical balloon catheter (IBC) is better than oxytocin for induction of labor in the setting of premature rupture of membranes (PROM) or breaking the bag of water prior to onset of…
- Trial name
- NCT03172858
- Testing
- Intracervical balloon catheter, Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Cervical Ripening, Pregnancy
General Drug Use-results Survey on PROPESS Vaginal Inserts in Treatment for Initiation of Cervical Ripening in Patients at Term (From 37 Completed Weeks of Gestation)
To confirm and consider the occurrence of important identified risks described in the Japanese Pharmaceutical Risk Management Plan (J-RMP) under conditions used in routine medical practice.
- Trial name
- NCT04773314
- Testing
- PROPESS Cohort
- Where
- Japan
- Volunteers
- 409 people
- Sponsor
- Ferring Pharmaceuticals
Labor, Induced, Cervical Ripening
Prehospital Cervical Ripening Before Induction and the Maternal Experience
This is a randomized study evaluating the impact of pre-hospital cervical ripening with a transcervical Foley balloon before labor induction in full-term pregnancies on the length of inpatient labor induction and maternal…
- Trial name
- "PRIME" (NCT01641601)
- Testing
- Outpatient transcervical Foley balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Failed Labour
Comparison of Pre-Induction Cervical Ripening
This study is designed to assess the effectiveness of a combination method of induction of labor using a urinary balloon catheter and prostaglandin gel.
- Trial name
- NCT01390233
- Testing
- Prepidil Gel, Urinary Balloon Catheter, Combined Urinary Catheter & Prepidil Gel
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of South Carolina
Pregnancy, Premature Rupture of Membranes
Cervical Ripening in Premature Rupture of Membranes
Premature rupture of membranes (PROM) is diagnosed by demonstrating amniotic fluid in the vaginal canal before the onset of labor.
- Conditions
- Pregnancy, Premature Rupture of Membranes, Preterm Premature Rupture of Membranes, Unfavorable Cervix
- Trial name
- NCT02314728
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Uterine Hemorrhage
Hysteroscopy and Misoprostol Project
To investigate if self-inserted vaginal misoprostol prior to outpatient hysteroscopy will lead to satisfactory cervical ripening, compared to placebo.
- Trial name
- NCT00363389
- Testing
- misoprostol and cervical ripening
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Ullevaal University Hospital
Cervical Dilation
Balloon Catheter for Cervical Ripening
Once admitted, women who will have a transcervical balloon catheter inserted for induction will be approached for participation in this study.
- Trial name
- 25148 (NCT02606643)
- Testing
- Slight traction, Foley Catheter to no traction
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- St. Louis University
Cesarean Delivery, Cervical Ripening
Latent Phase Membrane Stripping for Caesarean Section Reduction
In the Hospital Escuela, the availability of beds and criteria for admission to the intensive care unit ICU are not the same, the use of this marker is questionable, as it is affected by the level of complexity of care provided…
- Conditions
- Cesarean Delivery, Cervical Ripening, Latent Phase Labour
- Trial name
- DEMEM (NCT06809985)
- Testing
- Hamilton maneuver
- Where
- Honduras
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Labor, Induced
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by…
- Trial name
- TOLERANCE (NCT07288021)
- Testing
- Topical Analgesia with Lidocaine-Prilocaine cream
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Bnai Zion Medical Center
Cervical Dilation, Induction of Labor
Ultrasound Assessment of DILAPAN-S
The goal of this observational prospective study is to assess the change in Dilapan-S rod diameters using transvaginal ultrasound over a period of 12 hours in term women undergoing induction of labor.
- Conditions
- Cervical Dilation, Induction of Labor, Ultrasound Evaluation
- Trial name
- NCT04529837
- Testing
- Gauze, No gauze
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Unfavorable Cervix, Cervical Ripening
Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 in induction of labor at term.
- Trial name
- NCT02861079
- Testing
- Foley catheter, PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Failed Induction of Labor
Bishop Score and Transvaginal Ultrasound for Preinduction Cervical Assessment in Multiparas
To compare the ultrasonographic cervical length with the Bishop score in determining the administration of prostaglandin for preinduction cervical ripening in multiparous women at term.
- Trial name
- NCT01317823
- Testing
- Assessment of cervical status
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Labor Induction, Cervical Ripening
Trial of Foley Catheter With and Without Extra-Amniotic Saline Infusion for Labor Induction
The purpose of this study is to compare the efficacy of a transcervical Foley catheter with and without extra-amniotic saline infusion (EASI) for priming the cervix for labor.
- Trial name
- FOLEYEASI (NCT00442663)
- Testing
- Transcervical Foley Catheter, Transcervical Foley Catheter with an EASI
- Where
- 4 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham