Clinical trials: Cervical Spine Degeneration
Degenerative Disc Disease in Cervical Spine, Stenosis Cervical Spine
PMCF Study Fortilink-SC
This study is setup to be able to gather information on the safety and performance of the Fortilink-SC Ti cage of Paradigm Spine GmbH, up to one year after the surgery.
- Trial name
- NCT07834749
- Testing
- Cervical interbody fusion surgery (standalone)
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- BAAT Medical Products B.V.
Cervical Spine Degeneration, ACDF Surgery
Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy
The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving outcomes after hospital discharge for ACDF surgery.
- Trial name
- FAST-PT (NCT06202443)
- Testing
- Early PT, Delayed PT
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Vanderbilt University Medical Center
Degenerative Disc Disease, Cervical Spine Degenerative Disease
Retrospective Analysis of Patients Implanted With 2 Levels of Prodisc® C Vivo Devices
The objective of the study is to evaluate the safety and post-operative performance profile of the prodisc® C Vivo after implantation in comparison to the relevant clinical literature.
- Conditions
- Degenerative Disc Disease, Cervical Spine Degenerative Disease, Symptomatic Cervical Disc Disease, Cervical Spine Degenerative Disc Disease
- Trial name
- NCT07370493
- Testing
- Prodisc C Vivo
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Centinel Spine
Degenerative Disc Disease, Craniocervical Injuries
Posterior Cervical Fixation Study
The objective of this study is to evaluate the safety and performance of occipito-cervico-thoracic spine surgery using posterior fixation as measured by reported complications, radiographic outcomes, and patients reported…
- Conditions
- Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease
- Trial name
- NCT04770571
- Testing
- observational study
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- NuVasive
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Degenerative Spine, Degeneration of Lumbar Intervertebral Disc
Percutaneous Trans-facet Spine Fixation
Percutaneous Trans-facet Fixation Massoud-Goel Technique and Theory for Treatment of Degenerative Spine
- Conditions
- Degenerative Spine, Degeneration of Lumbar Intervertebral Disc, Degenerative Cervical Disc Disease, Ligamentum Flavum Hypertrophy
- Trial name
- Massoud-Goel (NCT07001969)
- Testing
- Massoud-Goel Technique and Theory, Percutaneous Trans-facet Fixation for Treatment of Degenerative Spine
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mahmoud Massoud
Cervical Spine Degeneration
Surgical Intervention on the Body-mind-spirit of Patients With Cervical Spine Surgery
The study aimed to evaluate if surgical intervention in patients with degenerative cervical diseases improves quality of life (QOL), lowers pain-induced mental impairment, improves psychologic health, and promotes spiritual…
- Trial name
- NCT06428981
- Testing
- degenerative cervical diseases
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Degenerative Disc Disease, Spondylolisthesis
Quintex® Follow-up After One Year Minimum
Prospective study, not randomised, non-interventional, monocentric, investigating an intended patient cohort of 60 patients already operated on the cervical spine due to degenerative disc disease of the cervical spine down to the…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Trauma, Spinal Stenosis
- Trial name
- Quintex (NCT04489394)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cervical Myelopathy, Cervical Radiculopathy
Long-term Follow-up Motion Analysis of ACD Versus ACDA
Rationale: Cervical degenerative disc disease (CDDD) is a common cause of cervical radiculopathy, myelopathy or myeloradiculopathy.
- Conditions
- Cervical Myelopathy, Cervical Radiculopathy, Spinal Stenosis, Spinal Disease
- Trial name
- NCT04545983
- Testing
- Motion Analysis
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Zuyderland Medisch Centrum
Lumbar Spine Degeneration, Cervical Spine Degeneration
Randomized Controlled Trial Comparing Irrisept Versus Normal Saline for Wound Irrigation After Posterior Spine Surgery
To compare post-operative wound complications in patients randomized to normal saline versus Irrisept solution and any other adverse reactions from the solution.
- Trial name
- Irrisept (NCT05408923)
- Testing
- saline 0.9%, (0.05% chlorhexidine gluconate (CHG) in sterile water)
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Degenerative Disc Disease, Cervical Spine Degeneration
Stand-Alone Cage Verus Anterior Plating for Anterior Cervical Discectomy and Fusion.
The purpose of this study is to compare the clinical results between two different techniques for ACDF: 1. Stand-alone ACDF, which means the placement of an interbody device (cage) without anterior fixation or plating; 2.
- Trial name
- NCT03312192
- Testing
- Interbody Cage, Interbody Cage and Anterior Plating
- Where
- United States
- Sponsor
- Rush University Medical Center
Cervical Spine Degeneration, Movement, Abnormal
Cervical Spine Motion in the Elderly
Rationale: Physiological motion of the cervical spine is a subject of interest for medical specialists. Segmental range of motion (sROM) has been most commonly used to define motion but inter- and intra-variability is large.
- Conditions
- Cervical Spine Degeneration, Movement, Abnormal, Aging
- Trial name
- NCT04222777
- Testing
- Cinematographic Recording
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Cervical Spine Degeneration
Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery
Nefopam is a benzoxazocine derivative which is non-opioid and non NSAIDs. The previous studies showed that nefopam can inhibit reuptake of serotonin, norepinephrine and dopamine.
- Trial name
- NCT03955705
- Testing
- Nefopam 20 mg/ml, Normal saline
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cervical Spine Disc Disease, Surgery
ACDF Comparison Trial
This research protocol seeks to compare radiological and clinical outcomes of cervical spine disease patients following standard-of-care anterior cervical discectomy and fusion (ACDF) using allograft fusion versus Cohere porous…
- Conditions
- Cervical Spine Disc Disease, Surgery, Fusion of Spine, Degenerative Disc Disease
- Trial name
- NCT03187171
- Testing
- Allograft Fusion, Cohere PEEK Fusion Group
- Sponsor
- Duke University