Clinical trials: Cervical Spine Disease
Degenerative Disc Disease, Degenerative Spondylolisthesis
Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion
The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT06000319
- Testing
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Induce Biologics USA Inc.
Balance, Postural, Gait
The Influence of Manual Therapy Applied to the Cervical Spine in the Prevention of Balance Disorders in the Elderly
Falling is a major trauma that can occur with aging, leading to very significant psychological and physical health effects with financial and societal consequences.
- Conditions
- Balance, Postural, Gait, Elderly
- Trial name
- ManEq (NCT05475652)
- Testing
- Manual therapy
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Degenerative Disc Disease in Cervical Spine, Stenosis Cervical Spine
PMCF Study Fortilink-SC
This study is setup to be able to gather information on the safety and performance of the Fortilink-SC Ti cage of Paradigm Spine GmbH, up to one year after the surgery.
- Trial name
- NCT07834749
- Testing
- Cervical interbody fusion surgery (standalone)
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- BAAT Medical Products B.V.
Spinal Fusion, Cervical Vertebral Fusion
Study of Titanium-Coated PEEK Cages for Degenerative Disc Disease
Prospective Follow-up study of CeSPACE XP coated PEEK cages for the treatment of degenerative cervical disc disease
- Trial name
- NCT03565224
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Aesculap AG
Cerebral Amyloid Angiopathy
Balance Eyesight and Muscle Tension in the Cervical Spine in Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy (CAA) is one form of disease of the small vessels of the brain and can cause frequent cerebral hemorrhages as well as other types of stroke.
- Trial name
- NCT05082194
- Testing
- balance with open and closed eyes
- Where
- Poland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Anna Olczak
Lumbar Intervertebral Disc Displacement, Cervical Intervertebral Disc Displacement
Disc Resorption in Lumbar and Cervical Disc Herniation Patients Receiving Integrative Korean Medicine Treatment
Measurement of herniated disc resorption and assessment of satisfaction regarding post-treatment state and integrative Korean medicine treatment through phone interview in 500 patients with MRI follow-up results receiving…
- Trial name
- NCT02841163
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 505 people
- Sponsor
- Jaseng Medical Foundation
Cervical Spondylosis
Magnetic Therapy and Cervical Stabilization Exercises in Cervical Spondylosis
The purposes of this study are to Investigate adding low frequency high intensity magnetic therapy to cervical stabilization exercises on pain intensity, function, ROM, cervical endurance, and cervical proprioception errors in…
- Trial name
- NCT05734924
- Testing
- low Frequency High Intensity magnetic therapy
- Volunteers
- 80 people
- Sponsor
- Delta University for Science and Technology
Analgesia
Ultrasound-Guided Intermediate Cervical Plexus or Cervical Erector Spinae Block for Anterior Cervical Spine Surgery
Neck pain and stiffness or sore throat, are common after anterior cervical spine surgery. Complications are rare but can be serious and even potentially life-threatening if they do occur.
- Trial name
- NCT05577559
- Testing
- intermediate cervical plexus block, Cervical Erector spinae block
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cervicobrachial Neuralgia, Lordosis
Cervicobrachial Neuralgia and Sagital Balance of the Cervical Spine
The aim of this observational study is to establish estimation of global lordosis of the cervical spine (from C3 to C7) in patients with cervicobrachial neuralgia.
- Trial name
- CNSBS-NCBES (NCT03397459)
- Testing
- Spine teleradiography EOS
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cervical Spondylosis With Myelopathy, Cervical Radiculopathy
Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty
This study will comprehensively evaluate the outcomes and endpoints of these two different FDA-approved artificial disc implants used to treat cervical spondylotic myelopathy and/or radiculopathy today: Biomet Zimmer Mobi-C and…
- Conditions
- Cervical Spondylosis With Myelopathy, Cervical Radiculopathy, Cervical Disc Herniation, Degenerative Disc Disease
- Trial name
- NCT05701059
- Testing
- Cervical arthroplasty, Semi-Constrained Nuvasive Simplify, Unconstrained Biomet Zimmer Mobi-C
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Cervical Radiculopathy
Dispersal Pattern for Spine Injections (Gadolinium Contrast)
This study will analyze injectate dispersal patterns after standard-of-care cervical epidural steroid injections using gadolinium as a marker and magnetic resonance imaging (MRI) to characterize the pattern.
- Trial name
- NCT02217280
- Testing
- Injection with Gadolinium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Missouri-Columbia
Cervical Disc Degenerative Disorder
M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study
Prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the treatment…
- Trial name
- NCT04982835
- Testing
- M6-C Artificial Cervical Disc, ACDF
- Where
- 21 sites in United States
- Volunteers
- 156 people
- Sponsor
- Orthofix Inc.
Cervical Spondylosis
Effect of Vestibular Rehabilitation on Evoked Myogenic Potentials in Patients With Cervical Spondylosis
This study will Investigate the effect of vestibular rehabilitation on: Primary outcomes: Vestibular evoked myogenic potentials, Balance,and Cervical proprioception.
- Trial name
- NCT07502625
- Testing
- Vestibular rehabilitation program, traditional physiotherapy
- Volunteers
- 62 people
- Sponsor
- Cairo University
Cervical Spondylosis
Comparison of the Effects of Different Manual Therapy Techniques in Patients With Cervical Spondylosis
Proprioceptive sensitivity decreases in individuals with neck pain compared to those without neck pain. While organizing the treatment program of patients with neck pain, evaluation of cervical proprioception and its addition to…
- Trial name
- NCT04777318
- Testing
- Conventional physiotherapy, Conventional physiotherapy and Muscle Energy Technique, Conventional physiotherapy and Cervical Mobilization Techniques
- Where
- Cyprus
- Volunteers
- 76 people
- Sponsor
- Eastern Mediterranean University
Ankylosing Spondylitis (AS), Spine Fracture
A Retrospective Cohort Study About Surgical Efficacy for Lower Cervical Fractures in Ankylosing Spondylitis
The purpose of this retrospective cohort study was to observe and compare the efficacy of anterior cervical long segment fixation, posterior long segment fixation, and combined anterior and posterior fixation for the treatment of…
- Trial name
- NCT06873074
- Testing
- anterior long segment cervical fixation, posterior long segment cervical fixation, combined anterior and posterior fixation
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhou Fang
Cervical Radicular Pain
Effect of Cervical Collar in Cervical Radicular Pain.
Objectives:The purpose of this study is to determine if use of nech collar (stiff or soft)will improve the possibility to obtain painrelief in patients with cervical radicular pain.
- Trial name
- NCT00395798
- Testing
- Soft or stiff cervical collar(device), neck school(behavior)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Ullevaal University Hospital
Whiplash Injury of Cervical Spine, Muscle Weakness
Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders
The aim of this prospective observational study is to investigate whether the presence or absence of directional preference impacts movement coordination impairments as measured in patients with Whiplash Associated Disorders…
- Trial name
- NCT06143228
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- D'Youville College
Cervical Disc Disorder With Radiculopathy, Spinal Stenosis
Comparative Study of Gene-Activated Bone Substitute "Histograft" for Lumbar and Cervical Spinal Fusion
The goal of this clinical trial is to evaluate the safety and efficacy of the combination product "Histograft", a bone substitute based on octacalcium phosphate (OCP) and plasmid DNA encoding VEGFA gene, in spinal fusion…
- Conditions
- Cervical Disc Disorder With Radiculopathy, Spinal Stenosis, Lumbar and Other Intervertebral Disc Disorders With Radiculopathy, Biomechanical Lesion, Unspecified
- Trial name
- NCT06365307
- Testing
- Osteoplastic material based on octacalcium phosphate and biologically active nucleic acids for bone tissue regeneration Nucleostim-VEGF ("Histograft"), Synthetic osteoplastic material based on β-TCP or bone autograft
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Histograft Co., Ltd.
Motor Imagery, Neck Pain
Motor Imagery Ability and Cervical Discogenic Pain
Background: The purpose of the study was to examine the motor imagery ability and its association with pain, functional status, neck awareness and depression levels in individuals with cervical discogenic pain (CDP).
- Conditions
- Motor Imagery, Neck Pain, Disc Herniation, Functional Status
- Trial name
- NCT06502236
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Diabetes, Cervical Myelopathy
Diabetes and Glycosylation in Cervical Spondylosis
The purpose of this study is to determine the relevant significance of diabetes on cervical disc degeneration, and correlate diabetic control (HgbA1C) with disc glycosylation profile in patients undergoing anterior cervical…
- Conditions
- Diabetes, Cervical Myelopathy, Cervical Spondylosis
- Trial name
- NCT02758899
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine