Clinical trials: Cervical Spine Disease
Cervical Spondylotic Myelopathy
Diffusion MRI in Cervical Spondylotic Myelopathy (CSM)
Patients who have been diagnosed with Cervical Spondylotic Myelopathy will be asked to undergo an MRI using diffusion basis spectrum imaging (DBSI) technology.
- Trial name
- CSM (NCT03296592)
- Testing
- MRI with DBSI technology
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Coma, Wounds and Injuries
Cervical Spine Clearance in Obtunded Trauma Patients
The optimal method of clearing the cervical spine in obtunded trauma patients is unclear. Computed tomography (CT) identifies most injuries but may miss ligamentous injuries.
- Trial name
- CSclearance (NCT00573014)
- Testing
- Cervical Spine Clearance
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- MetroHealth Medical Center
Cervical Spondylosis, Lumbar Spondylosis
Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery
A prospective, randomized, placebo controlled, double-blinded study at a single institution.
- Trial name
- NCT02276911
- Testing
- Ibuprofen, normal saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Thorax Injuries, Cervical Injury Spine
The Effect of Sensory Isolation on Anxiety in Magnetic Resonance Imaging
The aim of this study is to determine whether the use of earplugs and eye masks in adults reduces anxiety during Manyetic Resonance Imaging.
- Conditions
- Thorax Injuries, Cervical Injury Spine, Brain Trauma, Joint Trauma
- Trial name
- NCT07155863
- Testing
- Earplugs and eye mask
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ege University
Cervical Radiculopathy, Cervical Myelopathy
Prospective Comparative Analysis of ACDF vs Fusion Interbody Cages With nanoLOCK Osseointegrative Technology
Study team will plan a prospective, randomized control trial using our institution's spine clinical outcomes registry. Eligible patients undergoing ACDF (see inclusion criteria listed below) will be randomized to an Intervention…
- Trial name
- NCT05762055
- Testing
- Titan nanoLOCK interbody cage, ACDF interbody cage
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Temporomandibular Joint Disorders
Correlation Between Cervical Spine Muscle Disorders and the Occurrence of Symptoms of Temporomandibular Joint Dysfunction
This study evaluated the correlation between the occurrence of disorders of selected muscles of the cervical spine and the occurrence of symptoms of TMJ dysfunction
- Trial name
- NCT05740826
- Testing
- Algometer
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Intubating Condition
Universal Stylet Bougie in Patients with Cervical Neck Immobilization.
In patients with cervical spine injury, securing the airway while adequately immobilizing the cervical spine to avoid secondary neurological damage is very challenging.
- Trial name
- NCT06521749
- Testing
- USB as a stylet, USB as a bougie
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Theodor Bilharz Research Institute
Ossification of Posterior Longitudinal Ligament
Comparison of ACAF and ACCF in the Treatment of Cervical OPLL
Background: Dr. Shi recently proposed a new technique as Ossification of anterior decompression surgery, which is also called anterior controllable antedisplacement and fusion (ACAF) , for ossification of the posterior…
- Trial name
- ACAF (NCT03312985)
- Testing
- ACAF surgery, ACCF surgery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Changzheng Hospital
Degenerative Disc Disease
Trinity Evolution in Anterior Cervical Disectomy and Fusion (ACDF)
The purpose of this study is to utilize Trinity Evolution in conjunction with an interbody spacer and supplemental anterior fixation of the surgeon's choice and to follow the patients to measure the clinical outcomes and rate of…
- Trial name
- NCT00951938
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Orthofix Inc.
Temporomandibular Joint Dysfunction Syndrome
Temporomandibular Dysfunction in Patients With Cervical Disc Herniation
Cervical spine problems are associated with temporomandibular joint (TMJ) and related muscles.The aim of the present study was to investigate temporomandibular joint dysfunction (TMD) and pain in individuals with cervical disc…
- Trial name
- NCT06141863
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Cervical Spine Surgery, Pain Management
The Effect of High-thoracic Erector Spinae Plane Block on Postoperative Pain and Diaphragmatic Function in Posterior Cervical Spine Surgery
Posterior cervical spine surgery, often performed on older individuals with significant comorbidities, is one of the most painful surgical operations.
- Trial name
- NCT06721832
- Testing
- Erector spina plane block (ESP), Bupivacain (preoperative)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Cervical Spine Degenerative Disc Disease, Fusion of Spine, Cervical Region
Comparison of Outcomes Between Early Physical Therapy Intervention and Usual Care Following Anterior Cervical Fusion Surgery
Background: Early physical therapy (PT) intervention with emphasis on spinal stabilization has been shown to benefit individuals undergoing lumbar spinal surgery.
- Trial name
- ACF (NCT01519115)
- Testing
- early physical therapy intervention, usual care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Texas Woman's University
Facet Joints; Degeneration, Neuropathy
MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root.
- Conditions
- Facet Joints; Degeneration, Neuropathy, Neuralgia
- Trial name
- NCT01788410
- Testing
- Cryoablation under image guidance, MRI Seednet Cryotherapy System (Galil Medical)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Mechanical Neck Pain, Neck Pain
Dry Needling for Mechanical Neck Pain
Mechanical neck pain is one of the most common musculoskeletal disorders among adults. It is characterized by pain and stiffness in the cervical region, often related to poor posture, repetitive movements, or prolonged sitting.
- Conditions
- Mechanical Neck Pain, Neck Pain, Musculoskeletal Disorders, Cervical Spine Dysfunction
- Trial name
- NCT07368517
- Testing
- Dry Needling with Exercise, Conventional Physiotherapy with Exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Deraya University
Nasal Obstruction, Arthrosis
Role of Airtraq Mobile to Improve Intubation Conditions With Airtraq
Airtraq sp has been proven effective for intubating patients presenting with difficult airway. The Airtraq sp allows visualisation of the tracheal inlet only for the intubator.
- Trial name
- AirtraqMob (NCT02510924)
- Testing
- Tracheal intubation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Neck Pain, Back Pain
A Pilot Registry for Ultrasound-guided Pharmacopuncture
A pilot study of prospective resigstry to evaluate the safety and efficacy of ultrasound-guided pharmacopuncture for spinal disorders
- Trial name
- NCT06572579
- Testing
- Ultrasound-guided pharmacopuncture treatment
- Where
- 3 sites in South Korea
- Volunteers
- 50 people
- Sponsor
- Jaseng Medical Foundation
Neck Pain, Neck Pain Musculoskeletal
Neck Musculoskeletal Symptoms Among Turkish Endodontists
This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Musculoskeletal Assessment, Musculoskeletal Disorder of the Neck
- Trial name
- ENDO-NECK (NCT07516782)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlas University
Spinal Tumor
A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy
The goal of the first part of this clinical research study is to learn how to deliver more accurate radiation treatment of tumors in the spine.
- Trial name
- NCT01624220
- Testing
- Spinal SBRT (Standard Dose), Spinal SBRT (Higher Dose), Gold Seed Implantation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- M.D. Anderson Cancer Center