Clinical trials: Cervical Spine Fusion
Diet, Carbohydrate Loading
Carbohydrate Loading and Elderly Patients Undergoing Spine Surgery
Carbohydrate loading, the consumption of carbohydrates prior to surgery, is an example of preoperative nutrition that has provided many benefits to surgical patients.
- Trial name
- NCT05778487
- Testing
- Gatorade Thirst Quencher
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Horizon Health Network
Cervical Spine Degenerative Disease Nos, Cervical Spondylosis With Myelopathy
Baxter: Actifuse SHAPE vs DBX in ACC
The purpose of this single-center, prospective, randomized study is to determine the fusion rates along with the clinical outcomes of commercially available bone graft substitutes Actifuse mixed with bone marrow aspirate (BMA)…
- Trial name
- NCT02005081
- Testing
- Actifuse SHAPE, Autograft with Demineralized Bone Matrix
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Cervical Disc Degenerative Disorder, Cervical Fusion
Post-market Observational Clinical Study With the CE-marked Implantable Class IIb Medical Device "ITC CERVICAL"
The goal of this observational post-market study is to evaluate the clinical performance and safety of the ITC CERVICAL device, a CE-marked implantable cervical interbody fusion cage, in adult patients undergoing anterior…
- Trial name
- NCT07556978
- Where
- 2 sites in Italy
- Volunteers
- 32 people
- Sponsor
- MT Ortho s.r.l.
Other Fusion of Spine, Cervical Region
Enhanced Recovery After Surgery for Anterior Cervcial Spine Surgeries in Elderly Patients
Elderly patients are subjected to airway and other complications after cervical spine surgeries. The study aim to investigate the efficacy of sugammadex (vs. neostigmine) in the recovery after anterior cervical spine surgery.
- Trial name
- NCT04161508
- Testing
- Sugammadex Injection, Neostigmine Injection
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intervertebral Disk Degeneration
An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation
The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented anterior cervical discectomy and…
- Trial name
- NCT00310440
- Testing
- P-15 Synthetic osteoconductive bone substitute, Autologous bone
- Where
- 12 sites in United States, Canada
- Volunteers
- 319 people
- Sponsor
- CeraPedics, Inc
Ankylosing Spondylitis (AS), Spine Fracture
A Retrospective Cohort Study About Surgical Efficacy for Lower Cervical Fractures in Ankylosing Spondylitis
The purpose of this retrospective cohort study was to observe and compare the efficacy of anterior cervical long segment fixation, posterior long segment fixation, and combined anterior and posterior fixation for the treatment of…
- Trial name
- NCT06873074
- Testing
- anterior long segment cervical fixation, posterior long segment cervical fixation, combined anterior and posterior fixation
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhou Fang
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Cervical Spine Disease, Pain, Postoperative
Clinical Study on the Safety and Efficacy of the Minimally Invasive Ennovate® Method for Pedicle Screw Placement
The study's main purpose is the collection of clinical data on the patients benefit and safety of pedicle screw placement through an innovative minimally invasive surgical approach compared to the state of the art open surgical…
- Trial name
- MISPEC (NCT06960018)
- Testing
- Ennovate® Cervical, open surgical technique, Ennovate® Cervical, minimal invasive surgical technique
- Where
- 3 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Aesculap AG
Cervical Spine Fusion
Navigation Image Accuracy Test in Cervical Spine Surgery Using Anatase Spine Surgery Navigation System
The "Anatase" Spine Surgery Navigation System used in this study has obtained market approval in Taiwan(MOHW-MD-No.006663) and the United States (510(k) Numbers: K180523 and K220348).
- Trial name
- NCT06117267
- Testing
- Anatase Spine Surgery Navigation System
- Volunteers
- 8 people
- Sponsor
- China Medical University Hospital
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Cervical Radiculopathy, Cervical Myelopathy
The Collar Post Anterior Cervical Spine Surgery Study
The Anterior Cervical Discectomy and Fusion (ACDF) represents one of the most commonly performed spinal operations internationally, often in the context of symptomatic radiculopathy or myelopathy secondary to cervical…
- Trial name
- C-PASS (NCT03842072)
- Testing
- Cervical collar
- Where
- 2 sites in Canada
- Volunteers
- 244 people
- Sponsor
- Unity Health Toronto
Ossification of the Posterior Longitudinal Ligament
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far.
- Trial name
- NCT05019001
- Testing
- Laminoplasty, Laminectomy With Fusion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Cervical Disc Disorder With Radiculopathy, Spinal Stenosis
Comparative Study of Gene-Activated Bone Substitute "Histograft" for Lumbar and Cervical Spinal Fusion
The goal of this clinical trial is to evaluate the safety and efficacy of the combination product "Histograft", a bone substitute based on octacalcium phosphate (OCP) and plasmid DNA encoding VEGFA gene, in spinal fusion…
- Conditions
- Cervical Disc Disorder With Radiculopathy, Spinal Stenosis, Lumbar and Other Intervertebral Disc Disorders With Radiculopathy, Biomechanical Lesion, Unspecified
- Trial name
- NCT06365307
- Testing
- Osteoplastic material based on octacalcium phosphate and biologically active nucleic acids for bone tissue regeneration Nucleostim-VEGF ("Histograft"), Synthetic osteoplastic material based on β-TCP or bone autograft
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Histograft Co., Ltd.
Degenerative Disc Disease, Degenerative Spondylolisthesis
Assessing Safety of Cervical Spine Fusion With NMP®
The goal of this retrospective chart review study is to assess safety of NMP® in the treatment of cervical spine degenerative conditions by assessing the incidence and nature of AEs in follow-up (minimum of 90 days and up to 2…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis Cervical
- Trial name
- NCT07245940
- Testing
- Natural Matrix Protein (NMP) Fibers, Cervical interbody fusion
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Red Rock Regeneration Inc.
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cervical Radiculopathy
Evaluation of Cervical Fusion With DTRAX® Cervical Cage With DTRAX Bone Screw
This study is being conducted to assess the radiographic (x-rays and CT scans) and clinical outcomes for the use of DTRAX Cervical Cage with DTRAX Bone Screw for the treatment of degenerative disc disease at one disc level with…
- Trial name
- NCT02694250
- Testing
- DTRAX® Cervical Cage with DTRAX Bone Screw
- Where
- 7 sites in United States
- Sponsor
- Providence Medical Technology, Inc.
Cervical Radiculopathy, Myelopathy
Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy
The purpose of this study is to compare the safety and efficacy of Preservon(TM) treated allograft bone dowels to traditional freeze-dried allograft bone dowels (control) for fusion of degenerated cervical intervertebral discs in…
- Trial name
- NCT00344890
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- LifeNet Health
Cervical Myelopathy, Radiculopathy
Bone Marrow Aspirate Concentration in Posterior Cervical Fusion
The purpose of this research is to test if that combining bone marrow aspirate (removing bone marrow with a needle) concentration with locally harvested (collected) autograft (patient's own bone from another part of the body) for…
- Trial name
- BMAC (NCT02068547)
- Testing
- locally harvested autograft, demineralized bone matrix, and cadaveric allograft, Bone Marrow Aspirate
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Whiplash Symptoms
Randomized WAD Study
Background: The majority of patients suffering a whiplash injury (WAD) will recover, but some may have symptoms for years despite all kinds of conservative treatment.
- Trial name
- NCT01994044
- Testing
- Cervical fusion
- Where
- Sweden
- Sponsor
- Spinal Surgery Clinic, Strängnäs