Clinical trials: Cervical Spine Surgery
Cervical Spine Disc Disease, Surgery
ACDF Comparison Trial
This research protocol seeks to compare radiological and clinical outcomes of cervical spine disease patients following standard-of-care anterior cervical discectomy and fusion (ACDF) using allograft fusion versus Cohere porous…
- Conditions
- Cervical Spine Disc Disease, Surgery, Fusion of Spine, Degenerative Disc Disease
- Trial name
- NCT03187171
- Testing
- Allograft Fusion, Cohere PEEK Fusion Group
- Sponsor
- Duke University
Cervical Spine Degeneration, ACDF Surgery
Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy
The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving outcomes after hospital discharge for ACDF surgery.
- Trial name
- FAST-PT (NCT06202443)
- Testing
- Early PT, Delayed PT
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Vanderbilt University Medical Center
Pressure Injury, Dysphonia
Initial Increase in Cuff Pressure in Anterior Cervical Spinal Surgery
When the retractor blades oped and is positioned to provide the surgical access in the anterior cervical spine surgery, it cause the trachea to deviate laterally and pose pressure on the tissue between the retractor and the…
- Conditions
- Pressure Injury, Dysphonia, Dysphagia
- Trial name
- NCT03240042
- Testing
- nasotracheal intubation, orotracheal intubation
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Degenerative Disc Disease (DDD), Instabilities
PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.
In accordance with the European Medical Device Regulation MDR 2017/745/EU, the legal manufacturers of medical devices are obliged to evaluate medical devices with regard to their clinical performance and safety.
- Conditions
- Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
- Trial name
- NCT05489822
- Testing
- VERTICALE® Cervical System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Silony Medical GmbH
Degenerative Cervical Myelopathy
Conservative Care Versus Decompression Trial for Degenerative Cervical Myelopathy Pilot
This study is a pilot randomized clinical trial designed to test whether it is feasible to conduct a larger study comparing two standard treatments for mild degenerative cervical myelopathy (DCM).
- Trial name
- CADET-DCM (NCT07358273)
- Testing
- Decompression Surgery, Conservative Care
- Volunteers
- 56 people
- Sponsor
- McMaster University
Intubation, Intratracheal
Intubation Success Rate_Rigid Video Stylet Vs Video Laryngoscope
This study compare the intubation success rate between video laryngoscope and rigid video stylet in cervical spine surgery patients.
- Trial name
- NCT02769221
- Testing
- Rigid video stylet, Video laryngoscope
- Volunteers
- 370 people
- Sponsor
- Seoul National University Hospital
Cervical Spine Disease, Pain, Postoperative
Clinical Study on the Safety and Efficacy of the Minimally Invasive Ennovate® Method for Pedicle Screw Placement
The study's main purpose is the collection of clinical data on the patients benefit and safety of pedicle screw placement through an innovative minimally invasive surgical approach compared to the state of the art open surgical…
- Trial name
- MISPEC (NCT06960018)
- Testing
- Ennovate® Cervical, open surgical technique, Ennovate® Cervical, minimal invasive surgical technique
- Where
- 3 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Aesculap AG
Symptomatic Epidural Hematoma After Cervical Spine Surgery
Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery
The incidence and correlation of symptomatic epidural hematomas after cervical spine surgery was reviewed and analyzed, then it will provide reference to avoid the occurrence of this complication for the future clinical work.
- Trial name
- NCT05190276
- Volunteers
- 129 people
- Sponsor
- Peking University Third Hospital
Cervical Spine Fusion
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients…
- Trial name
- MCP (NCT05996133)
- Testing
- Bupivacaine Hcl 0.25% Inj, Normal saline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hartford Hospital
Dysphagia, GERD
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
The researchers wish to investigate whether proton pump inhibitors, administered prior to or after surgery, can reduce the incidence and/or severity of difficulty swallowing foods and/or liquids,following anterior cervical…
- Conditions
- Dysphagia, GERD, Degenerative Joint Disease
- Trial name
- NCT03488147
- Testing
- Esomeprazole
- Where
- 2 sites in United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cervical Spine Surgery
Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Posterior cervical spine surgery often requires a large posterior midline incision, resulting in poorly controlled postoperative pain, which arises from iatrogenic mechanical damage, intraoperative retraction, and resection to…
- Trial name
- NCT04974658
- Testing
- Inter-semispinal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Pain, Postoperative
Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery
The purpose of this study is to describe the biopsychosocial impact of caregivers in patients undergoing total knee arthroplasty, total hip arthroplasty, and cervical/thoracic/lumbar spine surgery.Defining such impacts may offer…
- Trial name
- NCT03059602
- Testing
- No specific treatment based intervention-health measurement instrument
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Diet, Carbohydrate Loading
Carbohydrate Loading and Elderly Patients Undergoing Spine Surgery
Carbohydrate loading, the consumption of carbohydrates prior to surgery, is an example of preoperative nutrition that has provided many benefits to surgical patients.
- Trial name
- NCT05778487
- Testing
- Gatorade Thirst Quencher
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Horizon Health Network
Skull Pin Insertion, Short Duration Analgesia
Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion
Skull pin insertion during craniotomies is a brief, intensely stimulating, painful stimuli occurring during the conduct of a neurosurgical or spine anesthetic.
- Trial name
- NCT01056224
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- University Health Network, Toronto
Surgical Intervention, Endotracheal Intubation
Evaluation of the Ambu ® aScope® for Tracheal Intubation in Difficult Airways
The purpose of this study is to evaluate a disposable fiberscope (Ambu ® aScope®) for tracheal intubation in difficult airways due to cervical immobilization by a cervical collar, and compare it to a conventional reusable…
- Trial name
- NCT01467739
- Testing
- Ambu ® aScope®, a conventional reusable fiberscope
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Lausanne Hospitals
Degenerative Cervical Myelopathy
Hand Dexterity Training in Degenerative Cervical Myelopathy (DCM)
This clinical study aimed to evaluate the effectiveness of a virtual reality-based training intervention for improving hand dexterity and promoting neuroplasticity in individuals with Degenerative Cervical Myelopathy (DCM) after…
- Trial name
- NCT06754072
- Testing
- Virtual Keyboard (VK) System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Radiculopathy
Outcome of Physiotherapy After Surgery for Cervical Disc Disease: a Prospective Multi-Centre Trial
Many patients with cervical disc disease have long-lasting and complex symptoms with chronic pain, low levels of physical and psychological function and sick-leave.
- Trial name
- NCT01547611
- Testing
- Customary treatment, Structured behavioural medicine program
- Where
- 2 sites in Sweden
- Volunteers
- 202 people
- Sponsor
- Linkoeping University
Cervical Spine Disease, Psychological Impairment
The Confounding Burden of Psychological Impairments in Cervical Spine Surgery
This is a single-center prospective randomized investigation of patients undergoing surgical arthrodesis for single or multi-level cervical disease, resulting in cervical radiculopathy.
- Trial name
- NCT03183713
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Cervical Spine Instability
Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
This study was done to compare the ease of tracheal intubation using the conventional C blade and the D blade of CMAC videolaryngoscope in patients undergoing cervical spine surgery.
- Trial name
- NCT05561231
- Testing
- Intubation with C blade, Intubation with D blade
- Where
- India
- Volunteers
- 68 people
- Sponsor
- King Edward Memorial Hospital, Mumbai