Clinical trials: Cervical Spine Surgery
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
Intubation; Difficult or Failed
Comparison of Two Different Lightwand Intubation Techniques in Cervical Immobilized Patients
This study compares two different approaches of lightwand intubation techniques in cervical immobilized patients.
- Trial name
- NCT06119360
- Testing
- Face-to-face approach, Conventional approach
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Cervical Stenosis, Cervical Spine
Evaluation of the Statistical Validity of Cervical Spine Measurements-Including Range of Motion, Strength, and Functional Test Results-for Return to Sport in Patients Who Have Undergone Surgery for Cervical Stenosis and/or Herniation.
Cervical stenosis is characterized by a narrowing of the spinal canal that exerts pressure on adjacent sensitive areas, potentially causing significant neck pain and cervicobrachial neuralgia accompanied by functional…
- Trial name
- RC REPRO (NCT07886112)
- Testing
- Questionnaires, Physical tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Cervical Spine Degeneration
Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery
Nefopam is a benzoxazocine derivative which is non-opioid and non NSAIDs. The previous studies showed that nefopam can inhibit reuptake of serotonin, norepinephrine and dopamine.
- Trial name
- NCT03955705
- Testing
- Nefopam 20 mg/ml, Normal saline
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Intraoperative Monitoring, Spinal Diseases
Intraoperative Monitoring (IOM) Patient Registry
The primary objective of this study is to evaluate the rate of new or worsening neurologic deficits and/or radiculopathy following lumbar or cervical surgery in light of IOM using neurological testing (motor and sensory) in the…
- Trial name
- IOM (NCT02187653)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- DC2 Healthcare
Analgesia
Inter-semispinal Fascial Plane Block (ISPB) Versus Erector Spinae Plane Block (ESPB) in Posterior Cervical Spine Surgery
Recent advances in regional anesthesia techniques have aimed to provide more targeted and effective pain relief. Among these, the erector spinae plane (ESPB) block, the multifidus cervicis plane (MCP) block, and the paraspinal…
- Trial name
- NCT07340801
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Spinal Curvature
Prospective Cohort Study of Outcome After Minimally Invasive Posterior Cervical Spine Surgery
In case of cervical foraminal stenosis without central stenosis, there are several options; anterior discectomy and fusion (ACDF), tubular retractor assisted micro-foraminotomy (MTPF) and posterior percutaneous cervical…
- Trial name
- PECD (NCT02486107)
- Testing
- surgical procedure
- Where
- 3 sites in South Korea
- Volunteers
- 156 people
- Sponsor
- Seoul National University Hospital
Postoperative, Pain
Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery
Patients undergoing spine surgery frequently experience significant pain after surgery. This can limit patient activity and hinder rehabilitation.
- Trial name
- NCT04646707
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Peripheral Nerve Disease, Muscular Injury
Innervation Characteristics and Determination of Nerve Entry Points of the Musculus Semispinalis Capitis
The aim of this study is to determine the innervation characteristics and nerve entry points of the musculus semispinalis capitis.
- Trial name
- NCT06569563
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Degenerative Disc Disease, Craniocervical Injuries
Posterior Cervical Fixation Study
The objective of this study is to evaluate the safety and performance of occipito-cervico-thoracic spine surgery using posterior fixation as measured by reported complications, radiographic outcomes, and patients reported…
- Conditions
- Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease
- Trial name
- NCT04770571
- Testing
- observational study
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- NuVasive
Cervical Spine Fusion
Navigation Image Accuracy Test in Cervical Spine Surgery Using Anatase Spine Surgery Navigation System
The "Anatase" Spine Surgery Navigation System used in this study has obtained market approval in Taiwan(MOHW-MD-No.006663) and the United States (510(k) Numbers: K180523 and K220348).
- Trial name
- NCT06117267
- Testing
- Anatase Spine Surgery Navigation System
- Volunteers
- 8 people
- Sponsor
- China Medical University Hospital
Central Cord Syndrome, Spinal Cord Injury
Surgical Management of Spinal Cord Injuries In Neck
ABSTRACT/EXECUTIVE SUMMARY BACKGROUND, SIGNIFICANCE \& RATIONALE: Between 10-20% of the more than 6000 cases of spinal cord injury seen annually in the North America have the clinical pattern of traumatic central cord syndrome…
- Conditions
- Central Cord Syndrome, Spinal Cord Injury, Quadriparesis
- Trial name
- CCSS (NCT00475748)
- Testing
- Early and late surgery for traumatic central cord syndrome
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maryland Department of Health and Mental Hygiene
Spine Fusion, Spine Disease
Erector Spinae Plane Block for Cervical Spine Surgery
The study aims to assess the interfacial plane blocks' effect on pain level, course of postoperative rehabilitation, and anti-inflammatory analgesic effect.
- Conditions
- Spine Fusion, Spine Disease, Spinal Disease
- Trial name
- NCT06393530
- Testing
- 0.9%sodium chloride, 0.2% ropivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Cervical Disc Degeneration
Real World Data Collection and Analysis on the Anterior Cervical Spine Surgery
This observational study aims to evaluate the efficacy and safety of anterior cervical spine surgery in patients with cervical degenerative disc disease
- Trial name
- ACCSS (NCT05602714)
- Testing
- Collection Data
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Tiantan Hospital
Craniocervical Surgery
Improved Understanding of Venous Drainage at the Cranio-cervical Junction : Study of Postoperative Venous Remodeling Following Surgical Treatment of Lesions of the Posterior Fossa or Posterior Approach of the Upper Cervical Spine.
In the literature, a dichotomous view of cerebral venous drainage is most commonly found. Thus, two drainage pathways are most often considered: the jugular vein network and the vertebral artery plexus.
- Trial name
- VENAMAP 2 (NCT07206667)
- Testing
- T1 GRE GADO MRI sequence
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Hoarseness, Intubation
Rigid Video Stylet Vs Conventional Lightwand Intubation
Lightwand is a useful alternative device for intubation but scooping movement can induce damage and microbleeding of oral mucosa, postoperative hoarseness,sore throat.
- Conditions
- Hoarseness, Intubation, Sorethroat
- Trial name
- Optiscope (NCT02073786)
- Testing
- Conventional lightwand intubation, Rigid video stylet
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Cervical Spondylosis
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant
The purpose of this study is to determine the recovery profiles after general anesthesia in patient undergoing anterior cervical spine surgery.
- Trial name
- NCT02819089
- Testing
- Dexmedetomidine, NSS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Pharyngeal Pressure Change
Using the High Resolution Impedance Manometry to Evaluate Swallowing Function After Cervical Spine Surgery
Dysphagia is a well-known complication following cervical spine surgery, including anterior or posterior approach. However, which muscle at oropharyngeal region weakness and the recovery course of these patients are still…
- Trial name
- NCT04123522
- Testing
- anterior approach, posterior appraoch
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital