Clinical trials: Cervical Spine Surgery
Auricular Acupressure, Cervical Spine Surgery
Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery
The primary objective of this study is to investigate the effectiveness of auricular acupressure in improving post-cervical spine surgery pain and heart rate variability in patients.
- Trial name
- NCT06087380
- Testing
- auricular acupressure, standard ward care
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Analgesia
Ultrasound-Guided Intermediate Cervical Plexus or Cervical Erector Spinae Block for Anterior Cervical Spine Surgery
Neck pain and stiffness or sore throat, are common after anterior cervical spine surgery. Complications are rare but can be serious and even potentially life-threatening if they do occur.
- Trial name
- NCT05577559
- Testing
- intermediate cervical plexus block, Cervical Erector spinae block
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Symptomatic Cervical Disc Disease
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease…
- Trial name
- SMART (NCT04012996)
- Testing
- prodisc C SK and/or Vivo, Mobi-C Cervical Disc
- Where
- 30 sites in United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Centinel Spine
Post Operative Pain, Cervical Spine Instability
Inter-semispinal Plane Block and Cervical Spine Surgery
The inter-semispinal plane (ISP) block is a novel ultrasound-guided technique that involves local anesthetic injection into the fascial plane between the semispinalis cervicis and semispinalis capitis muscles with subsequent…
- Trial name
- ISPB (NCT06003933)
- Testing
- Bupivacaine Hydrochloride, Lidocaine Hydrochloride, Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Yasser S Mostafa, MD
Anterior Cervical Spine Surgery
ACSS Approach on Dysphagia
Anterior cervical spine surgery (ACSS) is a procedure for the treatment of several neck problems. Even though the procedure is overall safe and effective, there are possible complications after surgery, which include problems…
- Trial name
- NCT07533864
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Intracranial Surgery, Extracranial Surgery
Product Surveillance Registry; Ear, Nose &Amp; Throat - NIM Vital Cohort
The purpose of this study is to confirm clinical safety and performance of Medtronic's NIM Vital™ System and accessories when used as intended in a real-world setting.
- Conditions
- Intracranial Surgery, Extracranial Surgery, Intratemporal Surgery, Extratemporal Surgery
- Trial name
- PSR-ENT (NCT06637995)
- Testing
- Intraoperative Nerve Monitoring
- Where
- Germany
- Volunteers
- 205 people
- Sponsor
- Medtronic
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Cervical Instabilities Spine, Spine; Instability
SYMPHONY™ OCT System for Instabilities of the Upper Thoracic and Cervical Spine
This will be a prospective, multi-centre study at a National Tertiary Referral Centre for spinal trauma and spinal cord injuries, serving a catchment area of 5 million people.
- Trial name
- NCT06816862
- Testing
- SYMPHONY™ OCT System
- Where
- Ireland
- Volunteers
- 35 people
- Sponsor
- University College Dublin
Radiculopathy, Myelopathy
RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery
A Prospective, open label, multi-center observational study of patients requiring surgical treatment at one or two (contiguous) cervical spine levels.
- Conditions
- Radiculopathy, Myelopathy, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- NCT02403453
- Testing
- Rhine Cervical Disc
- Volunteers
- 68 people
- Sponsor
- K2M, Inc.
Orthopedic Disorder of Spine, Neurologic Disorder
A fMRI Study of Compressive Spinal Cord
Cervical myelopathy (CM), a chronically compressive spinal cord lesion, is the most common cause of non-traumatic paraparesis/quadriparesis among the elderly.
- Trial name
- CSM Plasticity (NCT03504254)
- Testing
- MRI examination
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Cervical Spine Fractures, Cervical Spine Injury
Study on Orthosis in Cervical Spine Fracture Treatment
Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults.
- Conditions
- Cervical Spine Fractures, Cervical Spine Injury, Rigid Collar
- Trial name
- SOFT (NCT06848660)
- Testing
- A rigid cervical collar
- Where
- 6 sites in Sweden
- Volunteers
- 616 people
- Sponsor
- Uppsala University Hospital
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Dysphagia
Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Post-operative dysphagia is a significant issue following anterior cervical spine surgery. The investigators are studying the effects of perioperative 3% sodium chloride, given over a period of 24 hours, on post-operative…
- Trial name
- NCT03677310
- Testing
- 3% Sodium Chloride, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cervical Disc Herniation, Cervical Foraminal Stenosis
Endoscopic Posterior Cervical Foraminotomy Versus Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy
Cervical radiculopathy caused by cervical disc herniation or foraminal stenosis is a common condition that may result in upper limb pain, sensory disturbances, and motor deficits.
- Conditions
- Cervical Disc Herniation, Cervical Foraminal Stenosis, Cervical Radiculopathy
- Trial name
- ENDOFOR (NCT07894159)
- Testing
- Uniportal Endoscopic Posterior Cervical Foraminotomy, Anterior Cervical Discectomy and Fusion
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Deglutition Disorders
Reducing Dysphagia Associated With Anterior Cervical Spine Surgery by Maintaining Low Endotracheal Tube Cuff Pressure
Anterior cervical spine surgery (ACSS) is one of the most common procedures performed by spinal surgeons. It is associated with a 30-50% risk of developing swallowing difficulties (dysphagia).
- Trial name
- NCT00332683
- Testing
- Maintaining low (15mmHg) ETT cuff pressure, Maintaining a normal pressure in the ETT cuff
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Constriction, Pathologic, Spine Degeneration
Strategic Use of Big Data in Spine Surgery - Testing Digital Prediction of Outcome in Clinical Praxis
The goal of this prospective, multicenter clinical trial is to determine if the use of the postoperative outcome prediction model the Dialogue Support tool can alter postoperative patient-reported outcome and satisfaction…
- Conditions
- Constriction, Pathologic, Spine Degeneration, Surgery, Radiculopathy
- Trial name
- NCT05817747
- Testing
- Dialogue support tool
- Where
- 10 sites in Sweden
- Volunteers
- 900 people
- Sponsor
- Sahlgrenska University Hospital
Cervical Spinal Stenosis, Posterior Cervical Spine Surgery
Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical Surgery
Through a single-center, exploratory clinical study, the safety and effectiveness of using barb wire in the incision and suture of posterior cervical surgery in obese patients were evaluated, providing a basis for its wide…
- Conditions
- Cervical Spinal Stenosis, Posterior Cervical Spine Surgery, Barbed Suture
- Trial name
- NCT05895968
- Testing
- posterior cervical surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Revision Spine Surgery, Fusion of Spine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
To determine if a pre-operative ketamine infusion would provide a similar decrease in post-operative analgesic and opioid consumption as intra-operative ketamine, but expand the monitoring period through the post-operative phase…
- Conditions
- Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
- Trial name
- KIPSs (NCT06066879)
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AXIS Spine Center- a division of Northwest Specialty Hospital