Clinical trials: Cervical Stenosis
Esophageal Fistula, Esophageal Neoplasms
Removal of the Evolution® Esophageal Stent - Fully Covered
The CLARITY study is a clinical trial approved by US FDA to study the removal of the Evolution® Esophageal Stent-Fully Covered in malignant and benign indications.
- Conditions
- Esophageal Fistula, Esophageal Neoplasms, Esophageal Perforation, Esophageal Stenosis
- Trial name
- CLARITY (NCT01900691)
- Testing
- Evolution® Esophageal Stent - Fully Covered
- Where
- 11 sites in United States
- Volunteers
- 130 people
- Sponsor
- Cook Group Incorporated
Proprioceptive Disorders, Stenosis
Does the Degree of Cervical Stenosis Affect Proprioception?
Neck pain is a common health problem that negatively affects the quality of life of individuals of different age groups and most people experience this problem at some point in their lives.
- Trial name
- NCT06566573
- Testing
- Pain, Normal Range of Motion, Proprioceptive Sense
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Central Sensitisation, Cervical Spine Stenosis
Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain
The cervical spine is a structure that bears the weight of the head and has important functions, but is susceptible to mechanical stress and degenerative processes.
- Trial name
- NCT06967415
- Testing
- Pain, central sensitization,functional status and quality of life.
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Barrett Esophagus, Gastric Antrectomy Partial
Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy
Confocal endomicroscopy is an emerging technique that allows in vivo imaging of cells and tissue structures of the gastrointestinal mucosa, with a magnification of about 1000 times, guiding optical biopsies in real time.
- Conditions
- Barrett Esophagus, Gastric Antrectomy Partial, Biliary Duct Stricture, Pancreatic Duct Stricture
- Trial name
- NCT02284802
- Testing
- Confocal endomicroscopy
- Where
- Brazil
- Volunteers
- 87 people
- Sponsor
- Fauze Maluf Filho
Cervical Cancer
Fat Grafting for Vaginal Stenosis in Gynaelogical Cancer
The GRASS study looks at performing a technique called "Fat Tissue Grafting" to assess whether it can reduce the side effects of vaginal stenosis effects and improve the sexual function of participants who wish to preserve…
- Trial name
- GRASS (NCT06015360)
- Testing
- Fat Graft
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cervical Degenerative Disc Disease, Cervical Stenosis
Minimally Invasive Posterior Decompression of the Cervical Spine
Degenerative stenosis of the cervical spinal canal may be caused by the compression of the posterior part of the dural sac and spinal cord by the hypertrophied ligamentum flavum and facet joints, by the compression of the…
- Conditions
- Cervical Degenerative Disc Disease, Cervical Stenosis, Posterior Spine Surgery
- Trial name
- NCT06995300
- Testing
- minimally invasive decompression via the posterior approach
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Esophageal Cancer
Relationship Between Endoscopic Ultrasound Staging and Degree of Stricture in Esophageal Cancer
The primary objective of this study is to document all cases of EUS in patients with esophageal cancer and determine if the inability to advance the gastroscope beyond the tumor correlates with locally advanced disease stage at…
- Trial name
- ESOCA (NCT02372929)
- Testing
- Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AdventHealth
Esophageal Cancer
Clinical Efficacy and Safety of Endoscopic Dilatation With Eso-Filp in Benign Esophageal Strictures
Benign esophageal strictures are frequently seen in endoscopic practice and are caused by a variety of esophageal disorders, including peptic, radiotherapy-induced and caustic injuries, Schatzki ring, eosinophilic esophagitis…
- Trial name
- ESO-FLIP (NCT05725473)
- Testing
- Eso-Flip
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Clinico Humanitas
Stenosis Cervix
How to Avoid Cervical Stenosis After LEEP in High Grade Cervical Dysplasia?
Cervical stenosis may occur in up to 19% after conization. It is a cause of infertility and amenorrhea. This study will test a new device named DUDA Device ("Dispositivo Uterino para dilatar canal endocervical") placed just after…
- Trial name
- DUDA (NCT02500966)
- Testing
- DUDA device, LEEP
- Where
- Brazil
- Volunteers
- 265 people
- Sponsor
- Barretos Cancer Hospital
Pelvic Cancer, Cervical Cancer
Sexual Quality of Life of Patients With Gynecologic Cancer Treated With Brachytherapy.
Gynecologic cancer treatments (chemoradiotherapy, brachytherapy and surgery) greatly impact patients' sexual quality of life (QoL). Use of the vaginal dilators may reduce vaginal stenosis.
- Trial name
- Gyn&Co (NCT04184154)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Cervical Disc Disease, Cervical Stenosis
Is There a Risk of Perioperative Stroke Due to the Retraction Used During Anterior Cervical Discectomy?
In anterior cervical disc surgery, head and neck extansion position and, surgical retraction used while reaching the anterior surface of the cervical vertebra can be affect the carotid blood flow and constituting a risk for…
- Conditions
- Cervical Disc Disease, Cervical Stenosis, Cervical Disc Herniation
- Trial name
- NCT05717010
- Testing
- Near infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Samsun University
Postoperative Risk Factors for Patients With Carotid Artery Stenosis
The Predictive Value of Clinical Data on Perioperative and Postoperative Risk Events in Patients With Head and Neck Artery Stenosis
The Predictive Value of Clinical Data on Perioperative and Postoperative Risk Events in Patients With Head and Neck Artery Stenosis
- Trial name
- NCT06027463
- Testing
- Head and neck vascular recanalization
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Tang-Du Hospital
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Cervical Spinal Stenosis
Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block
The purpose of this study is to analyze the spread of local anesthetic using magnetic resonance imaging after thoracic 2 paravertebral block in patients with cervical radiculopathy.
- Trial name
- NCT05141136
- Testing
- Ultrasound probe sagittal group, Ultrasound probe transverse group
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Gangnam Severance Hospital
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Esophageal Cancer, Cancer of Gastro Esophageal Junction
Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent.
Self expandable stent (SEMS) constitutes the main palliative treatment in advanced esophageal cancer. The palliative effect of SEMS is immediate when it comes to relief of dysphagia.
- Conditions
- Esophageal Cancer, Cancer of Gastro Esophageal Junction, Palliative Treatment
- Trial name
- StentMig (NCT02166320)
- Testing
- Partially covered SEMS, Fully covered SEMS
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Back Pain Lower Back, Neck Pain
Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)
This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between…
- Conditions
- Back Pain Lower Back, Neck Pain, Radiculopathy Multiple Sites, Spinal Stenosis Cervicothoracic Region
- Trial name
- CORTISS (NCT07762170)
- Testing
- triamcinolone acetonide (Kenalog), Celestone Soluspan 6Mg/Ml Suspension for Injection, Depo-Medrol 40Mg/Ml Suspension for Injection
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Igor Wilderman. MD
Degenerative Disc Disease, Degenerative Spondylolisthesis
Assessing Safety of Cervical Spine Fusion With NMP®
The goal of this retrospective chart review study is to assess safety of NMP® in the treatment of cervical spine degenerative conditions by assessing the incidence and nature of AEs in follow-up (minimum of 90 days and up to 2…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis Cervical
- Trial name
- NCT07245940
- Testing
- Natural Matrix Protein (NMP) Fibers, Cervical interbody fusion
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Red Rock Regeneration Inc.