Clinical trials: Cervix
ASC-US, LSIL
HPV Test of Urine and Self Collected Vaginal Samples for Cervical Cancer Screening Study
This study is a prospective observational study of human papillomavirus (HPV) testing using urine and self-collected vaginal samples for women who have atypical squamous cells of undetermined significance(ASCUS) or low grade…
- Trial name
- NCT03409471
- Testing
- Flocked Swab, Cervical Brush, HPV assay
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Korea University Guro Hospital
Squamous Cell Carcinoma of Cervix
Simultaneously Integrated Dose Escalation for Locally Advanced Cervical Cancer
The purpose of this study is to determine the feasibility of minimal invasive surgical resection through simultaneously integrated dose escalation given concurrently with chemotherapy for locally advanced squamous cell cervical…
- Trial name
- Side (NCT02879214)
- Testing
- Simultaneous boost along with chemo
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sichuan Provincial People's Hospital
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery
This phase II trial studies the effects of temsirolimus in treating patients with cervical cancer that cannot be cured by standard therapy.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Recurrent Cervical Carcinoma
- Trial name
- NCT01026792
- Testing
- Temsirolimus, Laboratory Biomarker Analysis
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- National Cancer Institute (NCI)
Uterine Cervical Neoplasms, Cervical Cancer
Combination of PD-1 Monoclonal Antibody and HPV Vaccine in Patients With Cervical Cancer
The investigators propose to evaluate the efficacy of the combination of Pd-1 Monoclonal Antibody and HPV Vaccine in the patients with cervical cancer who fails in or can not endure the standard treatment
- Conditions
- Uterine Cervical Neoplasms, Cervical Cancer, Cervical Neoplasms, Cervix Cancer
- Trial name
- NCT04096911
- Testing
- Sintilimab, quadrivalent HPV vaccine
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Buhai Wang
Cervical Cancer, Cervical Abnormalities
Cervix Image Sharing Protocol (CISP)
The Clinical Epidemiology Unit in the Clinical Genetics Branch of the Division of Cancer Epidemiology, NCI has a strong interest in fostering cervical cancer prevention solutions for all kinds of settings, including lowresource…
- Trial name
- NCT03179306
- Where
- United States
- Volunteers
- 27,084 people
- Sponsor
- National Cancer Institute (NCI)
Fertility, Contraception
Regulation of Cervical Mucus Secretion
The purpose of this study is to help us determine how hormones impact the production of cervical mucus which is a fluid secreted by the opening of the uterus, also called the cervix.
- Trial name
- NCT02969590
- Testing
- Leuprolide acetate, Estrogen and Progesterone Replacement, Progestin
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cancer of Cervix, Apoptosis
Prognostic Role of Inhibitor of Apoptosis Protein Overexpression on Recurrence Rate in Cervical Cancer
Overexpression of inhibitors of apoptosis proteins (IAPs) in patients treated for locally advanced cervical cancer with exclusive radio-chemotherapy may have a prognostic role on the local recurrence rate at 24 months.
- Trial name
- EPIcol (NCT06147960)
- Testing
- Immunohistochemistry
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain, Acute, Pain, Procedural
RCT of Pain Perception With Fast and Slow Tenaculum Application
This project will be a randomized controlled trial (RCT) measuring pain perception with two different tenaculum placement techniques on the uterine cervix.
- Trial name
- NCT05458037
- Testing
- Speed of tenaculum application
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Cervical Cancer, HPV-Related Carcinoma
PRGN-2009 in Combination With Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer
This Phase 2 study will evaluate the efficacy and safety of PRGN-2009 in combination with pembrolizumab in patients with pembrolizumab-resistant recurrent or metastatic cervical cancer.
- Conditions
- Cervical Cancer, HPV-Related Carcinoma, HPV-Related Malignancy, Recurrent Cervical Carcinoma
- Trial name
- NCT06157151
- Testing
- PRGN-2009 plus Pembrolizumab
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Precigen, Inc
Medical Education, Ovarian Cancer
Ultrasound Training Program for Gynecologic Cancer Staging in Residents
This is a prospective, interventional study aiming to develop and validate an ultrasound training program for gynecology and obstetrics residents, focused on the staging of gynecologic cancers, including ovarian, endometrial, and…
- Conditions
- Medical Education, Ovarian Cancer, Endometrial Cancer, Cervix Cancer
- Trial name
- Ultra-teaching (NCT07028229)
- Testing
- Training Group
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Medical Induction of Labor Affecting Newborn
Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management
The study is intended to compare expectant management and on presentation labor induction in women with premature rupture of membranes. The means of labor induction and cervical ripening are either oxytocin or dinoprostone.
- Trial name
- NCT02825641
- Testing
- Oxytocin, Dinoprostone
- Where
- Israel
- Volunteers
- 458 people
- Sponsor
- Rambam Health Care Campus
Premature Birth
Vaginal Progesterone in Twins With Short Cervix
A Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial of Vaginal Progesterone to Prevent Early Preterm Birth In Twin Pregnancy with Short Cervix.
- Trial name
- NCT01812239
- Testing
- Vaginal Progesterone gel., fetal fibronectin swab.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Obstetrix Medical Group
Prostate Cancer, Glioblastoma
MRI Guided Radiotherapy and Radiobiological Data: the ISRAR Database (Irm Sequences for Radiobiological Adaptative Radiotherapy)
The MRI linac Unity is a major technological evolution in radiotherapy combining a linear accelerator with a 1.5T MRI (radiological quality).
- Conditions
- Prostate Cancer, Glioblastoma, Head and Neck Cancer, Kidney Cancer
- Trial name
- ISRAR (NCT06041555)
- Testing
- 3 MRI sequences (T2*, IVIM and Multi Echo-Gradient), without injection, are performed
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Human Papilloma Virus, Human Papilloma Virus Infection
Clinical Trial to Explore Papilocare Gel Efficacy to Repair of the Cervico-vaginal Mucosa With HPV High Risk Lesions.
Phase II, exploratory, randomized, open, controlled and parallel groups clinical trial to evaluate the effectiveness of exploratory gel Papilocare in the repair of the cervico-vaginal mucosa with lesions caused by HPV-HR.
- Conditions
- Human Papilloma Virus, Human Papilloma Virus Infection, Cervix Lesion
- Trial name
- PALOMA2 (NCT04199078)
- Testing
- Papilocare vaginal gel
- Where
- 19 sites in Spain
- Volunteers
- 164 people
- Sponsor
- Procare Health Iberia S.L.
Preterm
Cerclage Plus Progesterone vs Progesterone Alone in Twin Short Cervix
This study aims to compare the effectiveness of cervical cerclage combined with progesterone versus progesterone alone in preventing preterm birth among women with twin pregnancies and a short cervix (cervical length ≤ 30 mm).
- Trial name
- VNTWINC (NCT07372495)
- Testing
- Cervical cerclage, Progesterone
- Where
- 6 sites in Vietnam
- Volunteers
- 260 people
- Sponsor
- National Hospital of Obstetrics and Gynecology
Endometrial Carcinoma, Ovarian Cancer
AssociatiNG Bevacizumab bEmarituzumab for GynecoLogIcal CAncer
The aim of this study is to determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of bemarituzimab given in combination with a fixed dose of bevacizumab and to assess the clinical activity of the proposed…
- Conditions
- Endometrial Carcinoma, Ovarian Cancer, Cervix Cancer
- Trial name
- ANGELICA (NCT07146919)
- Testing
- Bemarituzumab, Bevacizumab
- Sponsor
- Centre Leon Berard
Cervical Cancer
Radical Trachelectomy for Women With Early Stage Cervical Cancer
The goal of this research study is to learn about quality of life, sexual functioning, and symptoms in women who have undergone abdominal radical trachelectomy for cervical cancer. This is an investigational study.
- Trial name
- NCT00813007
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Effects of Immunotherapy, Metastatic/Recurrent Cervical Cancer
Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer
To evaluate the tolerability and safety of axalimogene filolisbac 1 x 10^10 colony forming units (cfu) administered with prophylactic premedication in repeating 3-dose study cycles in women with persistent, metastatic, or…
- Conditions
- Effects of Immunotherapy, Metastatic/Recurrent Cervical Cancer, Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma
- Trial name
- NCT02164461
- Testing
- Axalimogene filolisbac
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Advaxis, Inc.
Previous Mid Trimester Miscarriage, Previous Preterm Birth
Arabin Pessary in Singleton Pregnancy
This was a retrospective study sharing the experience of women high risk for spontaneous preterm birth managed by Arabin pessary.
- Conditions
- Previous Mid Trimester Miscarriage, Previous Preterm Birth, Previous Cervical Surgery, Short Cervix on Ultrasound
- Trial name
- NCT04638023
- Testing
- Arabin pessary
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- National University of Malaysia
Cancer Cervix Uterus, Precancerous Lesions
The Effect of Physical Activity and Abstain From Smoking on the Precancerous Lesion
In this proposed project,investigators will estimate the effect of physical activity and abstain from smoking on the regression of precancerous neoplasia.
- Conditions
- Cancer Cervix Uterus, Precancerous Lesions, Smoking
- Trial name
- NCT03093623
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 446 people
- Sponsor
- Taipei Medical University