Clinical trials: Cervix
Preterm Birth, Short Cervix
Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled Trial
The purpose of this randomized control trial is to determine whether cervical pessary plus vaginal progesterone is superior to vaginal progesterone alone in decreasing preterm delivery rate, and improving perinatal outcome, among…
- Trial name
- NCT02470676
- Testing
- Pessary, Progesterone
- Volunteers
- 430 people
- Sponsor
- Hillel Yaffe Medical Center
Cervical Cancer
Pemetrexed Disodium in Treating Patients With Recurrent Cancer of the Cervix
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00087113
- Testing
- pemetrexed disodium
- Where
- 22 sites in United States
- Sponsor
- Gynecologic Oncology Group
Brain Cancer, Head and Neck Cancer
A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients
The purpose of this study is to determine the safety of Velcade when used with chemoradiation in cancer patients.
- Conditions
- Brain Cancer, Head and Neck Cancer, Cervix Cancer, Central Nervous System Neoplasms
- Trial name
- NCT00329589
- Testing
- Velcade (bortezomib)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Cervical Cancer
Laparoscopic Sentinel Lymph Node Localization in Operable Cervix Cancer
The purpose of this study is to evaluate the feasibility, safety and efficacy of laparoscopic ovarian transposition in women less than 40 years of age with locally advanced cervical squamous cell carcinoma
- Trial name
- NCT00205010
- Testing
- Lymphoscintigraphy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Uterine Cancer, Cervical Cancer
Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix
Proton beam radiation therapy is known to spare surrounding normal tissues from radiation. Proton beam radiation delivers less radiation beyond the area of the target tissues.
- Trial name
- NCT01600040
- Testing
- Proton radiation therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Cervical Cancer, Endometrial Cancer
Pelvic Fractures and Radiation Therapy for Cervical Cancer
The goal of this study is to estimate how often pelvic fractures occur in women treated with radiation therapy for either newly diagnosed or recurrent cervical, endometrial, or vaginal cancer.
- Conditions
- Cervical Cancer, Endometrial Cancer, Vaginal Cancer
- Trial name
- NCT00800644
- Testing
- CT or MRI + Blood Test
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Intraepithelial Neoplasia
A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins
The purpose of this trial is to evaluate if Straight Wire Excision of the Transformation Zone (SWETZ) is superior to (Large Loop Excision of the Transformation Zone) LLETZ cone in reducing the incomplete excision of disease.
- Trial name
- NCT01929993
- Testing
- SWETZ, LLETZ cone
- Where
- Brazil
- Volunteers
- 164 people
- Sponsor
- Oswaldo Cruz Foundation
Ovarian Cancer, Endometrium Cancer
Predictive Clinical and Biological Parameters in Gynecological Cancer
Research of predictive clinical and biological factors in breast cancer : genomic, proteomic, mutation
- Conditions
- Ovarian Cancer, Endometrium Cancer, Cervix Cancer
- Trial name
- GC-BIO (NCT01977274)
- Testing
- gynecological cancer
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Institut Paoli-Calmettes
Cervical Cancer
Prospective Evaluation of Intrafractional and Interfractional Cervical Motion During External Beam Radiation for Intact Cervical Cancer by the Calypso® 4D Localization System™
The purpose of this study is to find out how the cervix normally moves during radiation treatment. This study will also evaluate how cervical cancer shrinks during chemotherapy and radiation.
- Trial name
- NCT00907634
- Sponsor
- Emory University
Preterm Birth, Microbial Colonization
Vaginal, Placental and Neonatal Buccal Mycobiota and Microbiome in Preterm Birth
Microbiota contributes to the immunological, hormonal and metabolic homeostasis of the host. As in all natural orifices in the body, there is also a microbiota and mycobiota specific to the vagina.
- Trial name
- NCT04165252
- Testing
- Collection of vaginal, neonatal buccal and placental samples
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Koç University
Cervical Dysplasia
Digital Imaging Aid for Assessment of Cervical Dysplasia
The overall objective of this study is to evaluate whether polarized or green filtered digital imaging can assist clinicians to screen for premalignant lesions in the cervix.
- Trial name
- NCT00511758
- Testing
- Digital Imaging
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Preterm Birth, Pregnancy Trimester, Second
Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial
The aim of our study is to evaluate the effect of use of prophylactic vaginal progesterone on the incidence of severe preterm delivery, defined as delivery before 33+6 weeks in women with a short cervical length of 15mm.
- Trial name
- NCT00422526
- Testing
- Micronised progesterone (Utrogestan)
- Where
- 8 sites in Brazil, Chile and 2 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Cervix Cancer
Cervix Hypoxia FAZA
The purpose of this study is to look for low levels of oxygen (hypoxia) in your cervix cancer using a special x-ray test called a positron emission tomography (PET)scan.
- Trial name
- NCT01549730
- Testing
- 18F-Fluoroazomycin Arabinoside (18F-FAZA)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
HPV Infection, Cervix Cancer
Prevention and Screening Towards Elimination of Cervical Cancer
The research project applies the protocol of the World Health Organisation for screening of cervical cancer, with testing of hrHPV as first screening, followed by Visual Inspection of the cervix with Acetic Acid for…
- Conditions
- HPV Infection, Cervix Cancer, Cervical Dysplasia
- Trial name
- PRESCRIP-TEC (NCT05234112)
- Testing
- Community mobilisation for hrHPV self-testing, hrHPV self-testing, Follow-up after testing
- Where
- Uganda
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
High Grade Intraepithelial Neoplasia, Cervix Cancer
Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions
Cervical cancer is one of the leading malignancies affecting women, with 311,000 deaths in 2018, most of them seen in underdeveloped countries.
- Trial name
- NCT03233412
- Testing
- Control, Imiquimod
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Barretos Cancer Hospital
Cervix Cancer
Prospective Evaluation of Patients With Uterine Cervical Cancer in Brazilian Health Institutions - The EVITA I Study
The primary objective of this study is to describe the socio-demographic, clinical pathological, quality of life and treatment characteristics of patients diagnosed with CC in Brazil.
- Trial name
- NCT02671071
- Testing
- Quality of Life Questionnaire (QLQ)
- Where
- 16 sites in Brazil
- Volunteers
- 638 people
- Sponsor
- Latin American Cooperative Oncology Group
Healthy
Phase I Study of HAL Formulations Applied to the Cervix in Healthy Volunteers
The purpose of the study is to determine the most effective formulation of HAL for release of hexaminolevulinate to the cervical epithelium at different doses.
- Trial name
- NCT00496171
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- Photocure
Neoplasia of the Uterine Cervix, Cancer Prevention
HRME: Screening for Cervical Cancer and Its Precursors in Low-Resource Settings
A new mobile diagnostic and treatment unit is being developed by BCH to address the loss-to follow-up associated with the mobile screening program and demonstrate POC diagnosis by HRME.
- Conditions
- Neoplasia of the Uterine Cervix, Cancer Prevention, Cervical Intraepithelial Neoplasia
- Trial name
- HRME-UH2 (NCT02494310)
- Testing
- High-Resolution Microendoscopy Imaging
- Volunteers
- 200 people
- Sponsor
- Barretos Cancer Hospital
Premature Ejaculation
A Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment of Premature Ejaculation
A phase I, single-center, double-blind, randomized, placebo-controlled, safety and pharmacokinetic study to evaluate systemic and local vaginal exposure to lidocaine and prilocaine and the metabolites, 2,6-dimethylaniline…
- Trial name
- NCT01184105
- Testing
- Intervention A, Intervention B
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Cervical Cancer, Cervix Cancer
Anti-PD-1 Antibody Combined With Histone Deacetylase Inhibitor in Patients With Advanced Cervical Cancer
Cervical cancer is the second-most common cancer in the world and is a leading cause of cancer death among women in developing countries.
- Conditions
- Cervical Cancer, Cervix Cancer, Cervix Neoplasm
- Trial name
- NCT04651127
- Testing
- Toripalimab + Chidamide
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Sun Yat-sen University