Clinical trials: Cervix
Uterine Cervical Cancer, Uterine Cervix Cancer
Three Birds With One Stone
The overall aim of the study is to increase participation rates in cervical cancer (CCU) and colorectal cancer (CRC) screening programmes in Denmark by offering home-based CCU and CRC screening to women who are overdue for one or…
- Conditions
- Uterine Cervical Cancer, Uterine Cervix Cancer, Uterine Cervical Neoplasm, Colorectal Neoplasms
- Trial name
- NCT05022511
- Testing
- Screening status
- Where
- Denmark
- Volunteers
- 27,099 people
- Sponsor
- University of Aarhus
HSIL of Cervix
Clinical Study of HPV Therapeutic DNA Vaccine (NWRD08) in Patients With Cervical HPV16 and/or HPV18 Positive
This is an open-label exploratory clinical study. The main objective is to explore the immunogenicity of HPV therapeutic DNA vaccine NWRD08.
- Trial name
- NCT05905354
- Testing
- NWRD08
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Newish Technology (Beijing) Co., Ltd.
Preterm Birth, Short Cervical Length
The Impact of Vaginal and IM Progestins on the Cervix
The purpose of this study is to analyze how the body handles and responds to progesterone treatment in parous and nulliparous women at risk of pre-term birth.
- Trial name
- NCT01954095
- Where
- 4 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cervix Neoplasms, Uterine Neoplasms
Intensity Modulated Radiation Therapy - Gyne Cancer (GY03.2)
Standard treatment for gynecological cancer is radiation therapy in two phases; whole pelvic radiation and then an internal radiation boost, also called a brachytherapy boost, to treat any remaining tumour.
- Conditions
- Cervix Neoplasms, Uterine Neoplasms, Vaginal Neoplasms
- Trial name
- NCT00188578
- Testing
- Intensity Modulated Radiation Therapy Boost
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Cervical Cancer, Cervical Intraepithelial
Cervical Cancer Early Endpoints and Determinants
This study, conducted by the National Cancer Institute and the University of Oklahoma, will look for changes in cervix cells and other samples that may be signs of cervical disease.
- Conditions
- Cervical Cancer, Cervical Intraepithelial, Neoplasia, CIN
- Trial name
- NCT00339989
- Where
- United States
- Volunteers
- 3,013 people
- Sponsor
- National Cancer Institute (NCI)
Cervix Dysplasia, HPV Infection
DEFLAGYN® Vaginal Gel and Spontaneous Remission and Regression of Unclear Cervical Smears and HPV High-risk Infections
Human papillomaviruses (HPV) are the most common sexually transmitted pathogens worldwide and in most cases are causally associated with the development of cervical cancer, one of the most common cancers in women and one of the…
- Trial name
- HPV-VG1 (NCT05509413)
- Testing
- DEFLAGYN vaginal gel
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Ruhr University of Bochum
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery
This phase II trial studies the effects of temsirolimus in treating patients with cervical cancer that cannot be cured by standard therapy.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Recurrent Cervical Carcinoma
- Trial name
- NCT01026792
- Testing
- Temsirolimus, Laboratory Biomarker Analysis
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- National Cancer Institute (NCI)
Labor; Forced or Induced, Affecting Fetus or Newborn
Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix?
The goal of this study is to determine whether inducing labor with just one dose of misoprostol, followed by treatment with oxytocin, will still be effective enough to increase the chances of having a successful vaginal delivery…
- Trial name
- NCT02680314
- Testing
- Misoprostol
- Volunteers
- 243 people
- Sponsor
- Montefiore Medical Center
Cervical Cancer
Docetaxel in Treating Patients With Advanced Cancer of the Cervix
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of docetaxel in treating patients with advanced cancer of…
- Trial name
- NCT00003445
- Testing
- docetaxel
- Where
- Argentina
- Sponsor
- Grupo Oncologico Cooperativo del Sur
Cervical Cancer
Predictive Assays In Cervix Cancer
The experiments outlined in this proposal will compare a number of currently available techniques for assessing hypoxia and interstitial fluid pressures in patients with cervix cancer.
- Trial name
- NCT01181375
- Testing
- Tumour Biopsies and Blood Sampling
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University Health Network, Toronto
Renal Cell Carcinoma, Ovarian Cancer
A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
This is a single-center, double-arm, open-label study. this study plans to evaluate the safety and efficacy of CD70-targeting CAR-T cells in the treatment of CD70-positive advanced/metastatic solid tumors, and obtain recommended…
- Conditions
- Renal Cell Carcinoma, Ovarian Cancer, Cervix Cancer, Metastatic Cancer
- Trial name
- NCT06010875
- Testing
- CD70 CAR-T cells
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Chongqing Precision Biotech Co., Ltd
Cervix Cancer
Prediction of Clinical Response and Outcome in Uterine Cervix Cancer
Observational study based on the routine clinical treatment and diagnostic course, to correlate imaging features with outcome objectives.
- Trial name
- NCT01764217
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht Radiation Oncology
Cervical Cancer
Fluorine F 18 EF5 PET/CT Imaging in Patients With Locally Advanced or Recurrent/Metastatic Cervical Cancer
RATIONALE: Diagnostic procedures, such as fluorine F 18 EF5 PET/CT imaging, may help find oxygen in tumor cells. It may also help doctors predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00978874
- Testing
- fludeoxyglucose F 18, fluorine F 18 EF5
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cancer of Cervix
Para-Aortic Lymph Nodal Staging & Evaluation of Treatment Outcome by 18F FDG-PET in Advanced Cancer Cervix
18F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging has been extensively used in the evaluation of various malignancies and is rapidly being recognized as a mandatory investigations.
- Trial name
- NCT00193752
- Testing
- PET IMAGING
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
Cervical Cancer, Squamous Cell Carcinoma of Cervix
Intra-lesional Tumor Boost for Bulky Cervical Cancer
The goal of this clinical trial is to learn if adding a radiation boost (intra-lesional boost) works to treat patients with large-sized cervical cancer. It will also learn about the safety of this treatment.
- Trial name
- INTLECTUAL (NCT07435376)
- Testing
- intra-lesional boost IMRT, High Dose Rate Brachytherapy
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Seoul National University Bundang Hospital
Preterm Birth, Cervix; Pregnancy
Prospective Evaluation of Pathways for Preterm Birth
This is a single center, prospective cohort study of pregnant patients at high risk for spontaneous preterm birth: patient's with history of spontaneous preterm birth, patient's with a short cervix and patient's symptomatic for…
- Trial name
- PEPP (NCT05246579)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- John O'Brien, MD
Pregnancy
Pessary to Prevent Prematurity in Twins in Case of Short Cervix
For 25 years, the twin pregnancy rate has regularly increased in the majority of European countries and in the United States, by 35% between 1981 and 2006.
- Trial name
- PESSAR'ONE (NCT02328989)
- Testing
- Pessary
- Where
- 18 sites in France
- Volunteers
- 324 people
- Sponsor
- University Hospital, Toulouse
Premature Ejaculation
A Safety and Tolerability Study of Administration of PSD502
A Phase I, Single-Centre, Double-Blind, Randomised, Placebo-Controlled, Parallel Group, Pharmacokinetic and Safety Study to Evaluate Systemic Exposure and Local Vaginal Exposure to Lidocaine and Prilocaine and the Metabolites 2,6…
- Trial name
- NCT01183208
- Testing
- Intervention A, Intervention B, Intervention C
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Cervix Cancer, Endometrial Cancer
2D vs 3D Planning for High-Dose Rate (HDR) Gynecological Brachytherapy
Demonstrate the limitations of conventional dosimetry (2D) for the adjuvant brachytherapy treatment and assess whether tridimensional dosimetry relates more faithfully with the occurrence of adverse effects.
- Trial name
- NCT02091050
- Testing
- 2D HDR planning, 3D HDR planning
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- AC Camargo Cancer Center
Ovarian Cancer, Endometrial Cancer
GYNecologic Cancer-Related COGnitive Impairment
The goal of this study is to test a home-based and patient-tailored cognitive training intervention among gynecologic cancer patients who have completed chemotherapy and who have experienced cancer-related cognitive impairment.
- Conditions
- Ovarian Cancer, Endometrial Cancer, Cervical Cancers, Vulvar Cancers
- Trial name
- GYNCOG (NCT06662435)
- Testing
- GYNCOG
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University