Clinical trials: Cervix Uteri-Diseases
Stenosis Cervix
How to Avoid Cervical Stenosis After LEEP in High Grade Cervical Dysplasia?
Cervical stenosis may occur in up to 19% after conization. It is a cause of infertility and amenorrhea. This study will test a new device named DUDA Device ("Dispositivo Uterino para dilatar canal endocervical") placed just after…
- Trial name
- DUDA (NCT02500966)
- Testing
- DUDA device, LEEP
- Where
- Brazil
- Volunteers
- 265 people
- Sponsor
- Barretos Cancer Hospital
Cervical Insufficiency
Azithromycin for Cerclage Prophylaxis
The primary goal is to assess the effectiveness in pregnancy prolongation utilizing azithromycin at the time of transvaginal cervical cerclage placement.
- Trial name
- NCT07608562
- Testing
- Azithromycin Prophylaxis, Cefazolin, Progesterone
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Cervix Cancer, Endometrial Cancer
Prognostic and Diagnostic Added Value of Medical Imaging in Gynecological Cancer (PRODIGYN)
The goal of this observational study is to learn about the added diagnostic and prognostic value of advanced medical imaging procedures in cervical cancer, endometrial cancer and ovarian cancer.
- Conditions
- Cervix Cancer, Endometrial Cancer, Epithelial Ovarian Cancer
- Trial name
- PRODIGYN (NCT05855941)
- Testing
- FDG-PET/CT and FDG-PET/MRI
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Västerbotten
Colorectal Cancer, Breast Cancer
Effectiveness of Care in Certified Cancer Centres in Germany
Assessment of the effectiveness of care in certified cancer centres for eight cancer entities via a retrospective cohort study based on secondary data from statutory health insurance funds and population-based clinical cancer…
- Conditions
- Colorectal Cancer, Breast Cancer, Ovarian Cancer, Cervix Cancer
- Trial name
- WiZen (NCT04334239)
- Testing
- Oncological certification
- Where
- Germany
- Volunteers
- 670,000 people
- Sponsor
- Technische Universität Dresden
Cervix Cancer, Cancer Awareness
The Effect of Cervical Cancer Awareness Education Based on Mobile Application
Cervical cancer is one of the most common cancer types affecting women in our country and in the world and causing morbidity. However, the availability of a vaccine for cervical cancer, preventable risk factors and early…
- Conditions
- Cervix Cancer, Cancer Awareness, Mobile Application, HPV
- Trial name
- NCT06252012
- Testing
- Mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Cervical Dysplasia, Cervical Lesion
See and Treat in an Outpatient Setting in Women Above 45 Years With Cervical Dysplasia
The study will investigate if implementation of "see and treat" in the outpatient clinic can optimize the diagnosis, clinical follow-up and treatment of older women with positive cervical screening test.
- Conditions
- Cervical Dysplasia, Cervical Lesion, Cervix Disease
- Trial name
- NCT04298957
- Testing
- Cone biopsy
- Where
- 3 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- University of Aarhus
Cervical Cancer
A Prospective Study of Monitoring Immune Response in Locally Advanced Cervix Cancer
Perspectives: To analyse if the change of specific immune response will correlate with clinical effect of advanced cervix cancer after radio-chemotherapy.
- Trial name
- NCT03559803
- Testing
- Cisplatin
- Where
- 2 sites in China
- Volunteers
- 58 people
- Sponsor
- Sichuan University
Uterine Cervical Neoplasms, Cervical Cancer by FIGO Stage 2018
A Radiomic MRI Predictive Model for Response to Concomitant Chemoradiotherapy in Locally Advanced Cervical Cancer
Cervical cancer is the fourth most common cancer in women worldwide, with approximately 604,000 new cases in 2020.Treatment for locally advanced cervical cancer is based on a combination of radiotherapy and chemotherapy.
- Trial name
- EPICOL-R (NCT07305727)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cervical Cancer, Uterine Cancer
Bevacizumab and Paclitaxel for Neuroendocrine Tumors of the Cervix
Objectives: Primary: To estimate the efficacy of bevacizumab and paclitaxel in patients with recurrent small cell, large cell, and neuroendocrine cervical and uterine cancers, as measured by progression-free survival.
- Trial name
- NCT00626561
- Testing
- Bevacizumab, Paclitaxel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer
EF5 to Detect Tumor Hypoxia in Patients With Stage IIB, Stage IIIB, or Stage IVA Cervical Cancer
RATIONALE: Knowing the level of oxygen in tumor tissue may help predict the effectiveness of anticancer therapy. EF5 may be effective in measuring oxygen in tumor tissue and helping to predict the effectiveness of anticancer…
- Trial name
- NCT00049231
- Testing
- EF5, immunohistochemistry staining method, biopsy
- Where
- 5 sites in United States
- Sponsor
- Gynecologic Oncology Group
Cervix Cancer
Plan of the Day Radiotherapy
The study objectives are to improve the treatment of LACC patients and to increase knowledge of the potential benefit of the plan-of-the-day concept on side effects during and after radiotherapy.
- Trial name
- NCT05634681
- Testing
- Plan of the day, Standard plan
- Where
- Norway
- Volunteers
- 190 people
- Sponsor
- Oslo University Hospital
Cervical Intraepithelial Neoplasia
Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1
This study looks at immediate treatment of a cervix with CIN 1 versus regular six-month follow-up with colposcopy and treatment if CIN 1 progresses.
- Trial name
- NCT00156026
- Testing
- loop electrosurgical excision procedure (LEEP)
- Where
- 10 sites in Brazil, Canada
- Volunteers
- 415 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)