Clinical trials: Cesarean
Acute Pain Management, Caesarean Section
Transverse Abdominis Plane (TAP) Block Versus Transversalis Fascia Plane Block (TFPB) After Cesarean Delivery
Postoperative analgesia treatment methods are applied to the living in the operating room. It is a routine part of the process of these applications. It is necessary from medical and ethical perspectives.
- Trial name
- NCT06939725
- Testing
- Transversus abdominis plane (TAP) block, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Samsun University
Uterine Rupture Gravid
Uterine Rupture International Data Acquisition
Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality.
- Trial name
- URIDA (NCT03576950)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Obstetrical Complications, Hemorrhage
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean
A randomized placebo-controlled trial of 11,000 women to assess whether tranexamic acid as prophylaxis lowers the risk of postpartum hemorrhage in women undergoing a cesarean delivery.
- Conditions
- Obstetrical Complications, Hemorrhage, Labor and Delivery
- Trial name
- TXA (NCT03364491)
- Testing
- Tranexamic Acid
- Where
- 12 sites in United States
- Volunteers
- 11,000 people
- Sponsor
- The George Washington University Biostatistics Center
Postoperative Pain, Cesarean Section
Comparison of the Time to the First Rescue Analgesic Among Parturients Receiving Intrathecal Additive Fentanyl or Intrathecal Fentanyl With TAP Block or TAP Block Alone for Elective Cesarean Sections Under Hyperbaric Bupivacaine Spinal Anesthesia
The postoperative pain management after cesarean section under spinal anestheisa is done using various modalities. The commonly used regimens are systemic NSAIDs/Opioids, USG guided TAP block or Intrathecal additive Fentanyl or…
- Trial name
- NCT05550597
- Testing
- Fentanyl HCl, Bupivacaine 0.25% Injectable Solution
- Where
- Nepal
- Volunteers
- 93 people
- Sponsor
- Nepal Mediciti Hospital
Cesarean Section, Intrathecal Morphine
The Contribution of Intrathecal Morphine Administration to Postoperative Patient Satisfaction During Cesarean Delivery
Evaluating the contribution of intrathecal morphine administration to postoperative patient satisfaction during cesarean delivery with the QoR-40 (Quality of Recovery 40) patient satisfaction compilation quality scale, scored…
- Conditions
- Cesarean Section, Intrathecal Morphine, Quality of Recovery 40
- Trial name
- ITM (NCT06076018)
- Testing
- Group morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Placenta Previa
Efficacy of Topical Tranexamic Acid in Reducing Blood Loss During CS in Patients With Placenta Previa
Objectives: To evaluate the efficacy of topical tranexamic acid applied on the placental bed after placental delivery to reduce blood loss during cesarean delivery in women with placenta previa.
- Trial name
- NCT06515535
- Testing
- Topical tranexamic acid, Intravenous tranexamic acid
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Epidural Anesthesia, Cesarean Section
A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia
To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.
- Trial name
- PCEA (NCT03195309)
- Testing
- Ropivacaine, Fentanyl
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Placenta Accreta Spectrum, Placenta Previa
Hematological and Coagulation Markers in Predicting Placenta Accreta Spectrum in Placenta Previa
Placenta accreta spectrum (PAS) is a serious pregnancy complication where the placenta attaches too deeply into the wall of the uterus.
- Trial name
- NCT07826247
- Volunteers
- 130 people
- Sponsor
- Assiut University
Endometritis
Reduction of Endometritis After Cesarean Section With the Routine Use of Methergine
Endomyometritis is an "infection in the uterus". It can occur in up to 1 out of 5 women having unplanned cesarean deliveries. Antibiotics are routinely given at the time of Cesarean delivery, but the infection in the uterus can…
- Trial name
- NCT00858832
- Testing
- Methergine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Valve Heart Disease, Elective Cesarean Delivery
Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery
Rheumatic heart valve diseases are prevalent among the young people in Egypt secondary to the socioeconomic conditions. The goal of anesthetic management of these patients is maintenance of sinus rhythm, systemic blood pressure…
- Trial name
- NCT01571791
- Testing
- Ketorolac-Lidocaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Cesarean Section
Use of Cesarean Birth at Private Health Facilities in Lilongwe and Blantyre, Malawi
The purpose of the research study is to collect preliminary data to which future outcomes after implementing quality improvement projects or research will be compared.
- Trial name
- NCT04442997
- Where
- 3 sites in Malawi
- Volunteers
- 260 people
- Sponsor
- University of Colorado, Denver
Pain, Postoperative
Efficacy of Bupivacain Local Infiltration for the Management of Pain During Cesarean Section
This study aims to evaluate the effect of local administration of bupivacain in the cesarean section incision for postoperative pain control, using the visual analogue pain scale (VAS) and assessing the need for rescue analgesia…
- Trial name
- NCT05404490
- Testing
- Bupivacain
- Where
- Panama
- Volunteers
- 202 people
- Sponsor
- Saint Thomas Hospital, Panama
Cesarean Section
Cosmetic Outcomes With Tissue Adhesive (2-octylcyanoacrylate) or Staples in Repeated Cesarean Section
Recent clinical trials were developed to test the outcomes of skin closure with tissue adhesive, staples and monofilament synthetic suture after cesarean section with Pfannenstiel incision: both clinical outcomes such as blood…
- Trial name
- NCT04302597
- Testing
- Staples, Tissue adhesive
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Università degli Studi dell'Insubria
Spinal Anesthesia
Measuring Cerebrospinal Fluid (CSF) Glucose Levels in Patients Under Going an Elective Cesarean Section With Spinal Anesthesia
This study will determine the level of glucose (sugar) in the CSF (fluid that surrounds the spinal cord) in 30 subjects having spinal anesthesia for cesarean section using a bedside glucose meter.
- Trial name
- NCT01067560
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obstetrical Complications, Labor and Delivery Complication
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo.
- Conditions
- Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
- Trial name
- PRECEDE (NCT06605118)
- Testing
- Azithromycin Injection, Standard of Care Preoperative antibiotics
- Where
- 14 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Cesarean Section Complications, Wound Infection
Cesarean Section Skin Prep - Does Skin Preparation Pattern Affect Skin Bacterial Burden
Currently there is no study investigating best skin cleaning patterns prior to cesarean deliveries. As a result, doctors perform skin preparation using random unstudied techniques.
- Trial name
- NCT04345562
- Testing
- Skin preparation patterns with ChloraPrep 2 x 26 mL single
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Complications; Cesarean Section
Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
Opioid analgesic drugs are the main treatment of patients during anesthesia. Although highly effective, their use is not without problems. One is the increasing requirement of these address the same nociceptive stimulus.
- Trial name
- NCT02387060
- Testing
- H-Bupivacaine, Fentanyl
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Cesarean Sections
Delayed Umbilical Cord Clamping - C-section Pilot
This is a pilot study of delayed cord clamping (DCC) at progressively longer intervals (90 to 120 seconds) during elective cesarean deliveries of term infants.
- Trial name
- NCT02229162
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Davis
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota