Clinical trials: Cesarean Delivery; Neuraxial Opioids
Respiratory Depression
Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery
Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are given.Pathophysiological respiratory depression -failure to respond to hypercapnia or hypoxia - is challenging to measure…
- Trial name
- NCT02417038
- Testing
- Capnostream
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stanford University
Respiratory Depression
OSA Screen Negative With Spinal Duramorph
Non emergent scheduled cesarean sections will be consented to participate in this study of patients who have screened negative for obstructive sleep apnea and who are also BMI>/= 35 to have capnography monitoring postoperatively.
- Trial name
- NCT03151226
- Testing
- Capnography monitoring
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Intrathecal Morphine, Caesarean Section
Intravenous Nalbuphine for Prevention of Intrathecal Morphine-induced Nausea and Vomiting in Patients Undergoing Cesarean Section: A Double-blind, Randomized Controlled Trial.
We study efficacy of iv nalbuphine in prevention of intrathecal morphine-induced nausea and vomiting in patients undergoing cesarean section.
- Conditions
- Intrathecal Morphine, Caesarean Section, Postoperative Nausea and Vomiting, Neuraxial Opioid
- Trial name
- NCT06837129
- Testing
- A single dose of 4 mg iv nalbuphine
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lidocaine Infusion, Neuraxial Opioid
Effect of Lidocaine Infusion on Neuraxial Opioid-induced Pruritus After Cesarean Section
The aim of this study is to assess the efficacy and potency of lidocaine infusion as a preventive measure on pruritus response after injection of 200 micro gram morphine with bupivacaine subarachnoid block, spinal anesthesia, in…
- Conditions
- Lidocaine Infusion, Neuraxial Opioid, Pruritus, Cesarean Section
- Trial name
- NCT06225323
- Testing
- Lidocaine, Saline
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Aswan University
Anesthesia
Decreased Neuraxial Morphine After Cesarean Delivery
The purpose of this study is to compare 50mcg to 150mcg morphine in epidural for the goal of decreasing side effects of medication with lower dose in patients who receive a QL block
- Trial name
- NCT04279054
- Testing
- Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Alabama at Birmingham
Cesarean Delivery; Neuraxial Opioids
Respiratory Rate After Cesarean Delivery
The study proposal summarizes aspects related to respiratory rate in women who undergo spinal anesthesia for cesarean delivery who receive or do not receive neuraxial opioids
- Trial name
- NCT04250233
- Testing
- Respiratory Monitor
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids
Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery.
- Conditions
- Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids, Spinal Anesthesia for Cesarean Section, Dexmedetomidine
- Trial name
- NCT07567495
- Testing
- Clonidine, Dexmedetomidine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Respiratory Depression, Postoperative Pain
Incidence of Respiratory Depression in Cesarean Section
This study is designed to determine the incidence and severity of respiratory depression in elective cesarean section patients who have received a spinal or epidural narcotic called duramorph for management of postoperative pain.
- Trial name
- NCT01181843
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University