Clinical trials: Cesarean Section; Infection
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obstetrical Complications, Labor and Delivery Complication
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo.
- Conditions
- Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
- Trial name
- PRECEDE (NCT06605118)
- Testing
- Azithromycin Injection, Standard of Care Preoperative antibiotics
- Where
- 14 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Surgical Site Infection
Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section
The goal of this clinical trial is to evaluate whether local subcutaneous administration of gentamicin reduces the incidence of surgical site infection (SSI) following elective cesarean section.
- Trial name
- NCT07311395
- Testing
- Gentamicin, Standard antibiotic prophylaxis
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Surgical Site Infection
Chlorhexidine Versus Povidone-Iodine Antisepsis for Reduction of Post Cesarean Section Surgical Site Infection
There is no difference between using chlorhexidine-based antisepsis protocol versus povidone-iodine protocol in reduction of surgical site infection in women undergoing cesarean section.
- Trial name
- NCT02396329
- Testing
- Chlorhexidine, Povidone-Iodine
- Where
- Egypt
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Postpartum Infectious Morbidity in Cesarean Section Delivery
Role of Skin Cleansing and Prophylactic Antibiotic in Preventing Infectious Morbidity After Cesarean Section Delivery
This study aims to determine the effectiveness of skin cleansing and prophylactic antibiotics given to women undergoing a cesarean section for reducing the incidence of postpartum infectious morbidity and to assess potential…
- Trial name
- NCT03007706
- Testing
- Women undergo cesarean section delivery
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Raghda Gamal Mohamed
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Surgical Infection, Cesarean Section Wound
Evaluation of Surgical Site Infection After Cesarean Section
This study aims to investigate surgical site monitoring after cesarean section using a mobile application currently being developed.
- Trial name
- NCT07205939
- Testing
- Mobile Application usage
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sibel Bulut Haklı
Surgical Wound, Surgical Wound Infection
Caesarean Wound Dressing Removal Study
An open labelled randomised trial on the timing of wound dressing removal for emergency caesarean delivery in labour.
- Conditions
- Surgical Wound, Surgical Wound Infection, Cesarean Section Complications
- Trial name
- Cesarean (NCT05458518)
- Testing
- Cesarean wound dressing removal
- Where
- Malaysia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Site Infections
The Skin Prep Study
The investigators propose a randomized controlled clinical trial to determine the comparative effectiveness of chlorhexidine-alcohol and iodine-alcohol preoperative skin preparation for preventing surgical site infections at…
- Trial name
- NCT01472549
- Testing
- Iodine-alcohol, Chlorhexidine-alcohol
- Where
- United States
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infection Prevention
PROPHYLACTIC ANTIBIOTICS PRIOR TO CESAREAN SECTION IN OBESE WOMEN
Surgical site infections are common and a cause of major morbidity. They are also more common in obese women. Cesarean sections are the most common surgery performed in the United States, therefore pregnant women are being faced…
- Trial name
- NCT01810354
- Testing
- Cefazolin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Wound Infection
A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.
- Trial name
- NCT00528008
- Testing
- povidone-iodine solution, chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Cesarean Section Complications
RCT Investigating Pre-cesarean Vaginal Wash of Chlorhexidine vs Povidone-iodine for Patient With Ruptured Amniotic Membrane.
The objective of this study is to investigate if the rate of infectious morbidity is decreased with the use of chlorhexidine or povidone-iodine vaginal scrub before cesarean section after ruptured membranes.
- Trial name
- VAP (NCT03925155)
- Testing
- EZ scrub vaginal chlorhexidine 4% solution, 10% provodine-iodine vaginal preparation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Infection; Cesarean Section
Betadine Irrigation in Cesarean Section
The purpose of this study was to evaluate, for the first time in Literature, the effects of betadine washing versus normal saline washing after uterine closure in women undergoing cesarean section (CS) at ≥36 gestational weeks in…
- Trial name
- NCT02865993
- Testing
- betadine group, no betadine group
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
Vaginal Microbiota and Post-cesarean SSI
The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery.
- Trial name
- NCT06840041
- Testing
- Vaginal swab and culture
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Surgical Wound Infection
Vacuum Assisted Closure for Cesarean Section
To study if incisional vacuum-assisted closure can decrease the risk of infection in cesarean section incisions in the obese compared with standard sterile dressing.
- Trial name
- VACCS (NCT02390401)
- Testing
- Vacuum-assisted closure, Standard sterile dressing
- Where
- 4 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Microbial Colonization
Restoration of the Gut Microbiome After Cesarean Section
This study aims to develop a therapy for restoring the gut microbiome in infants born via CS. The Study will conduct a randomized, placebo-controlled feasibility trial to assess the ability of microbiome restoration by FMT and…
- Trial name
- RestoreGut (NCT06264219)
- Testing
- Microbiome restoration - FMT, Microbiome restoration - FVT, Vaginal birth, untreated control
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jakob Stokholm