Clinical trials: Cesarian Section
Spinal Anesthesia, Dexamethasone
Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
The goal of this clinical trial is to determine the effects of intravenous (IV) dexamethasone on spinal anesthesia in healthy women having an elective Cesarean delivery (CD) at the IWK Health Centre.
- Trial name
- NCT05731960
- Testing
- Dexamethasone, Metoclopramide
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- IWK Health Centre
Cesarean Section
Early Oral Intake of Different Types of Diets Affecting Gastrointestinal Function
The percentage of cesarean deliveries is on the rise, accounting for 30-40% of all deliveries in Taiwan. Following a cesarean delivery, a few doctors in Taiwan still adheres to the progressive eating regimen of "nothing per…
- Trial name
- NCT06316024
- Testing
- water, juice/sport drink group, Chewing gum group
- Volunteers
- 200 people
- Sponsor
- Chiayi Christian Hospital
Obstetric Pain, Cesarean Section
The Relationship Between Preoperative Serum Asprosin Level and Postoperative Analgesic Consumption in Patients Undergoing Caesarean Section
Adipokines are bioactive substances secreted from adipose tissue and have various functions on appetite, energy, lipid, carbohydrate metabolism, regulation of blood pressure, and inflammation.
- Conditions
- Obstetric Pain, Cesarean Section, Postoperative Pain
- Trial name
- NCT06304246
- Testing
- Measurement Pain Threshold, Measurement of Serum Asprosin
- Volunteers
- 25 people
- Sponsor
- Firat University
Uterine Atony With Hemorrhage
Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients
Postpartum hemorrhage remains a leading cause of maternal morbidity and mortality worldwide, even in high income countries. Uterine atony is estimated to cause 70-80% of postpartum hemorrhage.
- Trial name
- NCT03904446
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cynthia Wong
Pain
Spinal Anesthesia for Cesarean Delivery: Bupivacaine With or Without Fentanyl
The safest form of anesthesia for Cesarean section is a spinal anesthetic. All spinal anesthetics contain a local anesthetic and/or a narcotic.
- Trial name
- NCT00808327
- Testing
- Bupivacaine, Bupivacaine, fentanyl
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain Score (VAS)
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Post-dural puncture headache (PDPH) is a well-recognized and potentially serious complication of subarachnoid block. While advancements in spinal needle design have reduced its incidence in recent years, PDPH still affects a…
- Trial name
- NCT06607861
- Testing
- saline group, dexmedetomidine group, lidocaine group
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Minia University
Perineal Injury, Perineal Laceration, Tear, or Rupture During Delivery
Targeted Deep Pelvic Floor Muscle Physiotherapy Versus Antenatal Perineal Massage in Nulliparous Women
This prospective randomized clinical trial evaluates whether targeted deep pelvic floor muscle physiotherapy is more effective than standard antenatal perineal massage in reducing perineal trauma among nulliparous women.
- Trial name
- NCT07764068
- Testing
- Targeted Deep Pelvic Floor Muscle Physiotherapy, Standard Antenatal Perineal Massage
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Urinary Catheter, Cesarean Section
Comparison of Immediate Versus Delayed Removal of Urinary Catheter Following Elective Cesarean Section
The objective this trial is to compare immediate and 12 hours postoperative removal of urinary catheter after elective cesarean section; and whether early removal is associated with lower risk of urinary infection compared with…
- Conditions
- Urinary Catheter, Cesarean Section, Urinary Infection
- Trial name
- NCT02074852
- Testing
- Foley urethral catheter
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Akmal El-Mazny
Post-Dural Puncture Headache
The Influence of Needle Diameter on Post Dural Puncture Headache
The purpose of this study is to determine whether injection needle pen point type 'PP Gauge 25' should be recommended as a primary choice of needle (in stead of 'PP Gauge 27') for healthy pregnant women who at delivery (vaginal…
- Trial name
- NCT02827058
- Testing
- G25 pencil point needle, G27 pencil point needle
- Where
- 3 sites in Norway
- Volunteers
- 65 people
- Sponsor
- Helse Nord-Trøndelag HF
Vaginal Delivery, Cesarian Section
Modes of Delivery Impact Maternal Oxidative Stress Biomarkers and Dynamic Thiol Disulphide Homeostasis
Modes of delivery impact maternal oxidative stress biomarkers and dynamic thiol disulphide homeostasis
- Conditions
- Vaginal Delivery, Cesarian Section, Oxidative Stress
- Trial name
- NCT06826508
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Mardin Artuklu University
Postoperative Pain
Local and Intravenous Dexamethasone on Post Operative Pain a After CS
A Prospective, randomized study conducted on 120 pregnant women attending the labour wards in Kasr Al Ainy and Fayoum maternity hospitals from May 2014 to December 2015.
- Trial name
- NCT02784340
- Testing
- Dexamethasone, Saline (IV fluids), Bupivicaine and Fentany
- Volunteers
- 120 people
- Sponsor
- Cairo University
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Intravenous Lidocaine, Fundal Pressure
Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section
This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal…
- Conditions
- Intravenous Lidocaine, Fundal Pressure, Headache
- Trial name
- LID-HEAD (NCT07661758)
- Testing
- Lidocaine IV, Saline 0.9%
- Where
- Egypt
- Volunteers
- 680 people
- Sponsor
- Tanta University
Cesarean Section
Effect of Bioptron on Scar Formation After Cesarean Section
The purpose of the study will be to determine the effect of polarized light therapy (Bioptron) on scar formation after a cesarean section.
- Trial name
- NCT06796933
- Testing
- Silicon based products (silicon gel), Bioptron (polarized light therapy)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cesarean Birth, Spinal Anesthesia
Dexmedetomidine Versus Ketamine Loading for Dexmedetomidine Sedation During Elective Cesarean Section Under Spinal Anesthesia
This is a prospective, randomized, double-blind clinical study designed to compare the maternal and early neonatal effects of a loading dose of dexmedetomidine versus low-dose ketamine in parturients undergoing elective cesarean…
- Conditions
- Cesarean Birth, Spinal Anesthesia, Sedation
- Trial name
- Sedation (NCT07676955)
- Testing
- Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Pregnant, High Altitude
The Effect of Different Altitude Levels on Spinal Anesthesia in Cesarean Section Surgery
The aim of the researchers in this prospective study is to determine the differences, if any, in terms of anesthetic parameters among pregnant women who live at different altitudes and undergo cesarean section under neuraxial…
- Trial name
- altitude (NCT05715476)
- Testing
- cesarian surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Giresun University
Hypotension
Evaluation of NEXFIN During Cesarean Delivery to Detect Hypotension
Hypotension after spinal anesthesia for cesarean delivery occurs frequently. Oscillometric measurement gives intermittent informations. Nexfin, a continuous noninvasive device, could help to detect hypotension.
- Trial name
- NEXFIN-CESAR (NCT01732133)
- Testing
- Nexfin
- Where
- 2 sites in France
- Volunteers
- 171 people
- Sponsor
- Hopital Foch
Anesthesia, Analgesia
The Efficacy and Safety of S-ketamine in Elective Cesarean Section
During the past years, a large number of clinical trials have investigated the use of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist racemic ketamine as an adjunct to local anaesthetics, opioids, or other…
- Conditions
- Anesthesia, Analgesia, Depression, Cesarean Section
- Trial name
- ES-CS (NCT04657107)
- Testing
- S-ketamine, normal saline
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Complications of Pregnancy, Childbirth and the Puerperium
Non-Invasive Hemoglobin Monitoring of Women Undergoing Cesarean Delivery
The purpose of this study is to determine the normal hemoglobin curve during cesarean delivery and for the first 24 hours after surgery to aid in the creation of an algorithm to detect life-threatening bleeding earlier.
- Trial name
- NCT02275507
- Testing
- Masimo Rainbow Sensor
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Hypotension
Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery
Background and rationale: The best agent to prevent spinal-induced hypotension is still uncertain but norepinephrine showed fewer effects on heart rate and cardiac output.
- Trial name
- NORA-CS (NCT04560634)
- Testing
- Norepinephrine, ClearSight®, Edwards Lifescience, Irvine, CA
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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