Clinical trials: Cessation, Tobacco
Bladder Cancer, Cervical Cancer
Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking
RATIONALE: Stop-smoking plans, including counseling and nicotine replacement therapy, may help smokers quit smoking. It is not yet known whether counseling and the nicotine lozenge is more effective than counseling and the…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00365508
- Testing
- nicotine lozenge, nicotine patch
- Where
- 10 sites in United States
- Volunteers
- 642 people
- Sponsor
- Fox Chase Cancer Center
Tobacco Use Cessation
Optimizing the Tobacco Cessation Clinical Decision Support Tool.
The existing tobacco cessation best practice advisory (BPA) fires for providers (physicians, residents, fellows, midwives, nurse practitioners, physician assistants) during outpatient encounters when a patient is identified as a…
- Trial name
- NCT03714191
- Testing
- Patient Outcomes, Billing documentation, Regulatory
- Where
- United States
- Volunteers
- 54,417 people
- Sponsor
- NYU Langone Health
Smoking Cessation, Smoking, Cigarette
Randomized Trial of Electronic Cigarettes With or Without Nicotine in Smoking Cessation.
Background: Electronic cigarettes (EC) mainly containing nicotine (88-95 % of users) are widely and growingly used worldwide. It is estimated that there were 1.7 million daily users in France in 2016.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Electronic Cigarette
- Trial name
- ECSMOKE (NCT03630614)
- Testing
- Electronic cigarette without nicotine (ECwN) plus active varenicline tablets
- Where
- France
- Volunteers
- 650 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Smoking Cessation
Dissemination of Tobacco Tactics for Hospitalized Smokers
Nurse-administered smoking cessation interventions have been shown to be efficacious, but are seldom implemented due to lack of training and time.
- Trial name
- NCT01309217
- Testing
- Tobacco Tactics Intervention, Usual Care
- Where
- 6 sites in United States
- Volunteers
- 1,528 people
- Sponsor
- University of Michigan
Smoking Cessation, Nicotine Dependence
Neuropsychological Prognosis Factors of Smoking Cessation
The low overall effectiveness of available smoking cessation treatment so far, indicate the need for new and more efficacious ways to help smokers maintain abstinence. Smokers are a highly heterogeneous population.
- Trial name
- NCT01554436
- Testing
- neuropsychological assessment
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Montpellier
Tobacco Use Disorder
Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals
Nicotine addiction is a serious health problem in the United States; 46 million people smoke cigarettes, and 70% of those are trying to quit.
- Trial name
- NCT00308763
- Testing
- Nicotine Patch, Sustained Release Bupropion
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Tobacco Smoking
Pilot Testing a Computer Delivered Tobacco Cessation Intervention in Outpatient Clinical Settings: A Feasibility Study
The investigators have developed a hybrid computer- and person-delivered intervention, called "C-Raven" for smoking cessation that is tailored to people with tobacco use in Baltimore City.
- Trial name
- NCT05145738
- Testing
- C-Raven with avatar, C-Raven without avatar
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Tobacco Smoking
Enhancing Smoking Cessation in the Homeless Population
The goal of this research study is to enhance smoking cessation rates for homeless smokers. The original study design proposed to test the effects of 1) an Intensive Smoking Intervention, and 2) integrating alcohol abuse…
- Conditions
- Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
- Trial name
- NCT01932996
- Testing
- nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation
The lack of proven waterpipe smoking cessation interventions makes it important to explore interventions proven effective for cigarette smoking cessation.
- Trial name
- NCT02575183
- Testing
- Varinecline (Chantix), Behavioral Therapy
- Where
- 2 sites in Lebanon
- Volunteers
- 152 people
- Sponsor
- American University of Beirut Medical Center
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking
Web and Mobile Smoking Cessation
This study seeks to develop and then perform a controlled efficacy Randomized Controlled Trial assessing tobacco abstinence of a best-practices Web-based PC-delivered smoking cessation intervention (QuitOnline) compared to a…
- Trial name
- MobileQuit (NCT01952236)
- Testing
- Web+Mobile, Web Only
- Where
- United States
- Volunteers
- 1,266 people
- Sponsor
- Oregon Research Institute
Smoking
Tobacco Status Project: Social Media Intervention for Young Adult Smokers
This randomized clinical trial will test the efficacy of a Facebook intervention based on the Transtheoretical Model (Prochaska and DiClemente) and US Public Health Service Clinical Practice Guidelines with young adults who smoke…
- Trial name
- TSP (NCT02207036)
- Testing
- Facebook intervention, Smokefree.gov
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Mental Illness
Trial of Integrated Smoking Cessation, Exercise and Weight Management in Serious Mental Illness: TRIUMPH
This study will determine whether an 18-month practical tobacco smoking cessation program integrating weight management counseling and exercise will be superior to treatment as usual in achieving prolonged smoking abstinence in…
- Trial name
- TRIUMPH (NCT02424188)
- Testing
- TRIIUMPH Intervention
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Smoking Cessation
Goal2Quit + NRT Sampling
The goal of this work is to develop, systematically evaluate, and clinically test an integrated cessation intervention comprised of a depression-specific Behavioral Activation (BA) for cessation mobile app ("Goal2Quit") packaged…
- Conditions
- Cigarette Smoking, Smoking Cessation, Depression
- Trial name
- NCT03837379
- Testing
- Treatment as Usual, Goal2Quit + NRT Sampling
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Medical University of South Carolina
Tobacco Cessation, Health Warning Label
Health Warnings and Counseling for Smoking Cessation
Tobacco use remains persistently high across South Asia, despite numerous public health efforts, and continues to significantly contribute to the burden of non-communicable diseases (NCDs) such as cardiovascular disease…
- Conditions
- Tobacco Cessation, Health Warning Label, Hypertension, Non Communicable Chronic Diseases
- Trial name
- NCT07098065
- Testing
- Graphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention)
- Where
- Bangladesh
- Volunteers
- 3,400 people
- Sponsor
- Hitotsubashi University
Smoking Cessation, Weight Gain
Exenatide for Smoking Cessation and Prevention of Weight Gain
The purpose of this study is to determine if exenatide improves end-of-treatment smoking abstinence rates and to determine if exenatide mitigates post-cessation weight gain.
- Trial name
- NCT05610800
- Testing
- Exenatide 2 milligram (mg) Injection, Nicotine patch, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking
Korean Youth Smoking Cessation Study
Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. In Los Angeles, rates of morbidities due to cigarette smoking follow prevalence.
- Trial name
- NCT02021175
- Testing
- Tailored CBME Therapy via Technology, Standard of Care
- Where
- United States
- Sponsor
- University of California, Los Angeles
Male Infertility
Tobacco and Sperm Genome: Effects of Smoking Cessation
Tobacco is a male infertility risk factor. Many studies comparing smokers to non-smokers have shown effects on spermatogenesis and the quality of the male gamete.
- Trial name
- TABAGERM (NCT03552081)
- Testing
- Fragmented DNA evaluation in blood and semen samples
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
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