Clinical trials: Cessation, Tobacco
Nicotine Dependence, Substance Abuse
Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation
Background Smokers often reject drugs as smoking cessation aids. Nonpharmacological interventions are notoriously under-evaluated.
- Conditions
- Nicotine Dependence, Substance Abuse, Substance Dependence, Tobacco Dependence
- Trial name
- NCT00484692
- Testing
- sustained-release bupropion (Zyban(R)), Psychodynamic Model Training (R) = PDM(R)
- Where
- Austria
- Volunteers
- 779 people
- Sponsor
- Medical University Innsbruck
Tobacco Use Cessation
Inpatient Smoking Cessation Pilot Program
The investigators are implementing a stepwise approach to cessation with a public health focus to improve health outcomes for the investigators' pediatric patients.
- Trial name
- NCT05060965
- Testing
- Nicotine lozenge, Nicotine gum, Nicotine patch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation, Tobacco Dependence
tDCS as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy
As an add-on treatment to behavioural therapy for tobacco dependence, anodal transcranial direct current stimulation (tDCS) significantly increases the cessation rate compared to treatment with sham tDCS; endpoint analysis will…
- Trial name
- NCT01729507
- Testing
- tDCS, standardised behavioural therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Smoking Cessation, Smoking, Cigarette
Enhancing Self Regulation Among Smokers
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to smoking cues in individuals with nicotine dependence.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
- Trial name
- MIMIC (NCT04161144)
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Tobacco Smoking
Mindfulness Based Smoking Cessation Among Cancer Survivors
This study will examine the effect of a mindfulness-based smoking cessation program among cancer survivors.
- Trial name
- NCT04038255
- Testing
- Nicoderm C-Q Transdermal Product, Orientation session, Craving-to-Quit app
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Smoking Cessation
Integrating Tobacco Treatment Into Cancer Care: A Randomized Controlled Comparative Effectiveness Trial
There are currently over 11 million cancer survivors in the U.S. and survival rates are increasing. Unfortunately, 10-30% of cancer patients are current smokers at the time of diagnosis, and many of these patients have elevated…
- Trial name
- NCT01871506
- Testing
- Standard Care (SC), Intensive Counseling (IC)
- Where
- 3 sites in United States
- Volunteers
- 303 people
- Sponsor
- Massachusetts General Hospital
Tobacco Use Disorder, Psychiatric Disorder
Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial
Tobacco smoking is the leading preventable cause of morbidity and mortality worldwide. However, currently available treatments, including standard pharmacotherapy and behavioural support, are limited in their efficacy…
- Conditions
- Tobacco Use Disorder, Psychiatric Disorder, Nicotine Dependence
- Trial name
- NCT06534047
- Testing
- Brainsway H4 deep Repetitive Transcranial Magnetic Stimulation (rTMS) coil, Nicotine replacement
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Breast Cancer, Smoking Cessation
Brief Intervention for Tobacco and Alcohol Risk Reduction for Couple During Breast Cancer Treatment.
This study will examine the benefits of involving partner in a Screening, Brief Intervention and Referral to Treatment (SBIRT) program for tobacco and alcohol for women treated for breast cancer.
- Conditions
- Breast Cancer, Smoking Cessation, Alcohol Use, Unspecified
- Trial name
- IBMC (NCT04007549)
- Testing
- Brief motivational interview on tobacco/alcohol risk reduction
- Where
- France
- Sponsor
- Institut Bergonié
Tobacco Use Disorder
Smoking Termination Opportunity for inPatients
The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute smoking related illness, to assist patients through withdrawal by use of a…
- Trial name
- STOP (NCT01141855)
- Testing
- Champix, Counselling alone
- Where
- 3 sites in Australia
- Volunteers
- 392 people
- Sponsor
- The Queen Elizabeth Hospital
Tobacco Dependence
C-Raven, a Virtual Tobacco Cessation Intervention in the Community
In low-income housing units in Baltimore, the investigators propose to conduct a pilot two-arm hybrid type 1 effectiveness-implementation RCT comparing a) an avatar-delivered computerized intervention (CI) for tobacco cessation…
- Trial name
- NCT06545669
- Testing
- C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Tobacco Use Cessation, Tobacco Use Disorder
Treating Tobacco Dependence in Inpatient Psychiatry - 1
The purpose of this study is to test in a randomized clinical trial a series of hypotheses concerning the efficacy of an extended expert-system intervention plus nicotine replacement therapy (NRT) for treating tobacco dependence…
- Trial name
- NCT00136812
- Testing
- stage-tailored intervention
- Where
- 2 sites in United States
- Volunteers
- 224 people
- Sponsor
- Stanford University
Smoking Cessation, Weight Gain
Exenatide for Smoking Cessation and Prevention of Weight Gain
The purpose of this study is to determine if exenatide improves end-of-treatment smoking abstinence rates and to determine if exenatide mitigates post-cessation weight gain.
- Trial name
- NCT05610800
- Testing
- Exenatide 2 milligram (mg) Injection, Nicotine patch, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Cessation, Peripheral Artery Disease
Onsite Tobacco Cessation Treatment for Patients With PAD
Tobacco cessation treatment is needed for individuals with peripheral artery disease (PAD) to improve symptoms, lower cardiovascular risk, and prevent amputation.
- Trial name
- PAD (NCT05469698)
- Testing
- Tobacco Treatment Research Program Standard Care
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking in IBD Patients
Influence of Smoking Cessation or Switching to THS on Disease Activity in IBD Patients.
The main goal of this study is to evaluate the effects of smoking cessation or switching from cigarette smoking to THS (tobacco heat system) on the clinical course of UC (ulcerative colitis) and CD (Crohn´s disease) in adult…
- Trial name
- NCT05196282
- Testing
- Smoking cessation
- Volunteers
- 100 people
- Sponsor
- HaFCED e.K.
Breast Carcinoma, Caregiver
Provider Training in Increasing Patient Tobacco Cessation Counseling and Referrals for Patients With Cancer Undergoing Radiation Therapy
This pilot clinical trial studies how well provider training works in increasing patient tobacco cessation counseling and referrals for patients with cancer undergoing radiation therapy.
- Conditions
- Breast Carcinoma, Caregiver, Head and Neck Carcinoma, Lung Carcinoma
- Trial name
- NCT03135782
- Testing
- Communication Skills Training, Medical Chart Review, Questionnaire Administration
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Smoking Cessation, Nicotine Addiction
Nicotine Receptor Levels and Smoking Cessation
The investigators propose to use positron emission tomography (PET) imaging to determine whether nicotinic receptor availability at pretreatment predicts smoking cessation success.
- Trial name
- NCT01788943
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Dependence
Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab
The purpose of this study is to assess the bioequivalence between two new oral nicotine replacement therapy products and Nicorette® microtab.
- Trial name
- NCT01238640
- Testing
- Code STD, Code STE, Nicorette Microtab
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- McNeil AB
Tobacco Dependence, PTSD
Behavioral Activation for Smoking Cessation in PTSD
The purpose of this study is to examine whether behavioral activation as an adjuvant to standard smoking cessation treatment improves smoking cessation outcomes among veterans with PTSD relative to a comparably intense…
- Trial name
- NCT01995123
- Testing
- Behavioral Activation Therapy, Health and Smoking Education, Standard Smoking Cessation Therapy
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Smoking Reduction, Smoking Behaviors
Assessment of the Pivot Breath Sensor: Single-Arm Cohort Study
Prospective open label, single center study enrolling up to 220 participants to evaluate the effect of the Pivot Breath Sensor on a user's attitudes towards quitting smoking and smoking behavior.
- Conditions
- Smoking Reduction, Smoking Behaviors, Smoking, Tobacco, Smoking Cessation
- Trial name
- NCT04133064
- Testing
- Pivot Breath Sensor
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD
Smoking, Cancer
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Little is known about what factors influence parental decisions to participate or to decline participation in tobacco trials offered in the pediatric clinical setting.
- Conditions
- Smoking, Cancer, Sickle Cell Disease
- Trial name
- NCT01673243
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
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