Clinical trials: Cessation of Smoking
Nicotine Addiction
Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers
Background: Central nicotinic acetylcholine receptors (nAChRs) are primary targets for the action of nicotine. In addition to being involved in tobacco dependence, they are also involved in a variety of brain disorders, including…
- Trial name
- NCT01038245
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking ( Cigarette)
Ecological Momentary Assessment of Smoking Triggers, Needs, and Cigarette Forgoing
This study will evaluate a smartphone-based program designed to support adults who smoke cigarettes. Participants will use the spark app to complete brief surveys during the day and a daily evening survey about their smoking…
- Trial name
- spark Forgo (NCT07852845)
- Testing
- Non-Adaptive Motivational EMI, Adaptive Motivational EMI
- Volunteers
- 45 people
- Sponsor
- University of South Carolina
Depression, Tobacco Use Disorder
Use of a Smartphone Mobile Application (App) to Enhance Smoking Cessation Treatment
This trial studies how well smartphone mobile applications work in enhancing smoking cessation treatment in current smokers. Smartphone mobile applications may help current smokers quit smoking.
- Conditions
- Depression, Tobacco Use Disorder, Current Every Day Smoker
- Trial name
- NCT03519451
- Testing
- Internet-Based Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study
This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, Lung Cancer
- Trial name
- NCT02076061
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lund University
Nicotine Dependence
Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study
The purpose of this study is to compare the effects of self-help materials for smoking cessation and self-help materials for smoking cessation plus prize-based contingency management (CM), in which prize incentives are available…
- Trial name
- NCT00408265
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- UConn Health
Tobacco Use Cessation
Effectiveness of a Chat Bot for Smoking Cessation: a Pragmatic Trial in Primary Care.
This study aims to evaluate the effectiveness of an intervention to help people to quit smoking throughout an chat bot compared with usual assistance to increase long-term rates of nicotine abstinence in smoking outpatients with…
- Trial name
- Dej@lo (NCT03445507)
- Testing
- Chat bot, Usual care
- Where
- Spain
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Smoking Cessation
Efficacy and Safety Following Use of a Novel Nicotine Replacement Therapy
A comparison of a novel nicotine replacement therapy and placebo treatment in smokers motivated to quit smoking.
- Trial name
- NCT00882375
- Testing
- Nicotine
- Where
- 3 sites in Denmark, Germany
- Volunteers
- 479 people
- Sponsor
- McNeil AB
Nicotine Dependence
A Smoking Cessation Treatment for Adult Women
The purpose of this study is to develop and pilot test a smoking cessation counseling that focuses on the perceived risks of quitting smoking (e.g., weight gain, managing cravings and negative affect, loss of enjoyment).
- Trial name
- NCT01422239
- Testing
- Tailored treatment, Standard Treatment
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Focus: Smoking Cessation as it Relates to Fracture Healing
Smoking Cessation Intervention Within the Fracture Clinic
Tobacco use is the leading preventable cause of death contributing to more than 5 million estimated deaths per year globally. The longterm negative effects of smoking are well established.
- Trial name
- NCT02891265
- Testing
- Smoking cessation patch
- Where
- 2 sites in Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Tobacco Use Cessation
Usefulness of Selegiline as an Aid to Quit Smoking - 1
Despite the widespread use of nicotine replacement therapies for the treatment of nicotine dependence, many smokers are still unable to quit smoking.
- Trial name
- NCT00129311
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation, Health Behavior
A Health Recommeder System to Tailor Message Preferences in a Smoking Cessation Programme
Patients attending the smoking cessation programme at the Virgen del Rocío University Hospital under the SoLoMo clinical trial of the SmokeFreeBrain project and provided with the SoLoMo mobile app will be observed for one year.
- Conditions
- Smoking Cessation, Health Behavior, Smoking, Tobacco, Smoking
- Trial name
- NCT03206619
- Testing
- Social, Local and Mobile
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Seville
Tobacco Use Cessation, Second Hand Tobacco Smoke
Families Reduce Exposure to Smoke at Home
This project proposes to evaluate the effectiveness of training Head Start staff to discuss tobacco use, shs reduction and cessation in their existing encounters with parents in reducing tobacco use and exposure.
- Trial name
- FRESH (NCT02557919)
- Testing
- Motivational Interviewing Training, Usual Best Practice
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Smoking Cessation
Facilitating Smoking Cessation With Reduced Nicotine Cigarettes
STUDY 1: INTERVENTION DEVELOPMENT The purpose of this study is to determine the best way to help people stop smoking by using very low nicotine content (VLNC) cigarettes.
- Trial name
- NCT02796391
- Testing
- Very Low Nicotine Content (VLNC) Cigarettes, One on One Counseling
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Tobacco Dependence
Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab
The purpose of this study is to assess the bioequivalence between two new oral nicotine replacement therapy products and Nicorette® microtab.
- Trial name
- NCT01238640
- Testing
- Code STD, Code STE, Nicorette Microtab
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- McNeil AB
Smoking Cessation, Smoking Behaviors
Nurse-led Smoking Cessation Program With Follow-up in Healthy Life Centres: a Randomized Clinical Trial
A better understanding of how to incorporate effective smoking cessation measures into clinical practice is requested. In this is prospective, multi-center, randomized, open, blinded end-point (PROBE) trial, we assigned daily…
- Conditions
- Smoking Cessation, Smoking Behaviors, Nurse's Role, Cardiovascular Diseases
- Trial name
- NCT05049174
- Testing
- Nuse-led interview and referral to municipal healthy life-centres
- Where
- 3 sites in Norway
- Volunteers
- 221 people
- Sponsor
- Vestre Viken Hospital Trust
Tobacco Use, Smoking
A Facebook Intervention for Young Sexual and Gender Minority Smokers
The 2-year research plan will test the Put It Out Project (POP) in a pilot randomized trial (N=120) compared to TSP and two historical control conditions.
- Conditions
- Tobacco Use, Smoking, Tobacco Dependence, Tobacco Use Disorder
- Trial name
- POP (NCT03259360)
- Testing
- POP:, TSP:
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Improving Smoking Cessation Outcomes in Heavy Drinkers - 1
To test the effectiveness of an smoking cessation treatment for smokers who also drink alcohol heavily.
- Trial name
- NCT00107575
- Testing
- Standard treatment plus brief alcohol intervention, Standard treatment (ST)
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Brown University
Smoking, Smoking Cessation
Couples Dynamics and Smoking Cessation
This study is about investigating smoking and attempts to quit smoking in couples. Participation will help determine better treatment efforts for couples who want to quit smoking.
- Conditions
- Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors
- Trial name
- SCOR (NCT03885336)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Southern California
Smoking Cessation, Smoking Cessation Counseling Ability and Practice
Evaluating the Impact of CONNECT in a Multilingual Population
This study aims to broaden the reach of the lung cancer screening (LCS) CONNECT program (NCT04149249, NCT06213532), by developing a version of the program to be available to multilingual communities.
- Conditions
- Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
- Trial name
- CONNECT-ML (NCT07111936)
- Testing
- CONNECT Intervention for multilingual populations, Saliva Sample, Interview
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Comparing Smoking Treatment Programs for Lighter Smokers - 1
The purpose of this study was to compare two different types of Food and Drug Administration (FDA) approved smoking cessation medications (nicotine patch or bupropion) used in conjunction with two levels of counseling.
- Trial name
- NCT00086411
- Testing
- nicotine transdermal system, bupropion, Medication Management
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania