Clinical trials: Challenging Behaviour, active
Autism, Challenging Behavior
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental…
- Conditions
- Autism, Challenging Behavior, ADHD, Oppositional Defiant Disorder
- Trial name
- Footsteps (NCT07042347)
- Testing
- Behavioral economics strategies, Electronic platform
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Challenging Behavior
A Single-Arm Pilot Trial for Mitigating Relapse of Severe Problem Behavior
The goal of this study is to improve how we teach self-control and communication skills to children and adolescents with challenging behaviors.
- Trial name
- NCT06732219
- Testing
- Functional Communication Training, Extinction-Correlated Stimuli, Caregiver Fading
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Auburn University
Harmful Stereotypies, Feeding Difficulties
Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities
Adults with developmental disabilities (DD) and autism represent a vulnerable demographic that transitions into adulthood with diverse etiologies, exhibiting a significantly higher prevalence of various challenging behaviors.
- Trial name
- NCT06920615
- Testing
- Fading and chaining combined with differential reinforcement, Differential reinforcement of high rate, Response interruption with redirection
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Aging, Adults With Overweight and Obesity
Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in Adults With a Metabolically Challenging Profile
Early-onset metabolic disturbances (such as mild hyperglycemia, subclinical dyslipidemia, excess body fat, and reduced functional capacity) represent one of the major public health challenges among middle-aged and older adults.
- Conditions
- Aging, Adults With Overweight and Obesity, Supplementation, Exercise
- Trial name
- NCT07504068
- Testing
- Group 1: Exercise + thermogenic supplement (EX-TS)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- University of Valencia
Smoking Behavior, Special Needs Child
Evaluation of the Effects of Passive Smoking and Parental Stress on Challenging Behaviors in Mentally Retarded Children With Urine Cotinine Levels
This research was planned to determine the effect of environmental cigarette smoke exposure and parenting stress level on the severity of challenging behaviors in mentally disabled children
- Trial name
- smoking (NCT06691022)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Autism Spectrum Disorder
Effectiveness of Parent-Mediated Intervention Combined With Positive Behavioral Support on Challenging Behaviors and Parenting Stress Among Children With Autism.
This study aims to evaluate the effectiveness of a parent-mediated intervention combined with Positive Behavioral Support (PBS) in reducing challenging behaviors among children with autism and decreasing parenting stress in South…
- Trial name
- NCT07570550
- Testing
- Parent-Mediated Intervention + Positive Behavioral Support (PMI + PBS)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Islamia University of Bahawalpur
Intellectual Disability, Autism Spectrum Disorder
Harnessing Communication Preferences
The goal of this clinical trial is to evaluate how preference for communication approach (e.g., using a touch talker versus picture cards) impacts treatment maintenance in the context of treatment to reduce challenging behavior…
- Conditions
- Intellectual Disability, Autism Spectrum Disorder, Self-Injurious Behavior, Communication Disabilities
- Trial name
- NCT07278544
- Testing
- PrefFCT, NonPrefFCT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Joel E. Ringdahl
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Autism Spectrum Disorder
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study.
The investigation team propose in this study to specifically evaluate the feasibility of using oxytocin in the form of an intranasal spray in a specific population of children with autism spectrum disorder and intellectual…
- Trial name
- OT-DEFI (NCT05864508)
- Testing
- Oxytocin nasal spray
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Autism Spectrum Disorder (ASD)
TeleABA for Hospitalized Adolescents and Young Adults With Autism Spectrum Disorder
This study is evaluating whether a telehealth-based applied behavior analysis (ABA) program can improve the care of adolescents and young adults with autism spectrum disorder (ASD) who are hospitalized because of severe…
- Trial name
- NCT07701915
- Testing
- Standard Hospital Care, Telehealth Applied Behavior Analysis (TeleABA)
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Caring Technologies, Inc.
Adherence, Medication, HIV Infections
Optimizing Care for Challenging People Living With HIV
Conduct an intervention combining social and behavioral health models with digital health technologies to improve their adherence to their medication schedules.
- Conditions
- Adherence, Medication, HIV Infections, Social Media
- Trial name
- NCT06183723
- Testing
- Combination of social-behavior model and eHealth
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Challenging Behavior, Autism Spectrum Disorder
Measurement of Treatment Effects
The overall objective is to evaluate and compare the efficacy of two common treatments for CB in children and adolescents with autism using multiple outcome measures.
- Trial name
- NCT07024303
- Testing
- Psychotropic medication (at discretion of psychiatrist), Behavioral therapy
- Volunteers
- 20 people
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic)
Regulating Emotions and Behaviors After Brain Injury
After acquired brain injury (ABI), persons can experience emotional and behavioral difficulties, that can be painful both for the person and his/her family.
- Conditions
- Acquired Brain Injury, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic), Brain Tumor (After Recovery), Encephalitis
- Trial name
- GREMO-LCA (NCT05393492)
- Testing
- Dialectical Behavior Therapy and Radically Open dialectical behavior therapy
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Problem Behavior, Aggression
Manualized Assessment and Treatment Model of Challenging Behavior
Despite decades of mounting single-case-design evidence for the efficacy of applied behavior analysis (ABA) and other approaches for the assessment and treatment of challenging behavior, an evidence-based comprehensive approach…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05928247
- Testing
- Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey