Clinical trials: Change; Mental
Major Depression
Secondary Prevention of Depression Applying an Experimental Attentional Bias Modification Procedure
Depression (Major Depressive Disorder; MDD) has been dubbed "the common cold among the mental illnesses" and it is also a highly recurrent disorder.
- Trial name
- NCT02658682
- Testing
- Attention Bias Modification
- Where
- 2 sites in Norway
- Volunteers
- 350 people
- Sponsor
- University of Oslo
Severe Mental Illness, Schizophrenia
The Potential Efficacy of the Chinese Health Improvement Profile- A Pilot Clustered Randomised Controlled Trial
The investigators programme of research will evaluate an existing physical health care screening intervention with the aim of helping Community Psychiatric Nurses (CPN) to improve the physical health wellbeing of people with a…
- Conditions
- Severe Mental Illness, Schizophrenia, Schizoaffective Disorder, Bipolar Affective Disorder
- Trial name
- CHIP (NCT02453217)
- Testing
- Chinese CHIP, Treatment as usual
- Volunteers
- 144 people
- Sponsor
- Wai-Tong Chien
Binge Eating Behaviour, Binge Eating/Loss of Control Eating
Impact of the EXOMIND (BTL-699-2) on the Brain Reward Pathway
The goal of this clinical trial is to thoroughly explore and ascertain the mechanism of action of the therapy with the EXOMIND (BTL-699-2) device in the treatment of food cravings (serving as an important precipitant to binge…
- Conditions
- Binge Eating Behaviour, Binge Eating/Loss of Control Eating, Food Craving
- Trial name
- NCT07024550
- Testing
- Treatment with BTL-699-2 device, Treatment with BTL-699-2 device with intensity below therapeutic threshold
- Where
- Czechia
- Volunteers
- 8 people
- Sponsor
- BTL Industries Ltd.
Schizophrenia, Bipolar
Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine
The goal of this research is investigating the heart rate changes in schizophrenic and bipolar patients under the medication of aripiprazole and quetiapine.
- Trial name
- HeartAriQue (NCT01047215)
- Testing
- Aripiprazole; Quetiapine
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Body Weight Change, Schizophrenia
Effects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Disorder
The primary purpose of this study is to compare the affects of aripiprazole and olanzapine on weight change.
- Conditions
- Body Weight Change, Schizophrenia, Schizoaffective Disorder, Psychotic Disorder
- Trial name
- NCT00095524
- Testing
- Aripiprazole
- Where
- 32 sites in United States, Brazil and 1 more
- Volunteers
- 300 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Epilepsy, Mental Disorders
Stimulation-Induced Changes in Fronto-Limbic Network
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation.
- Trial name
- Stim_Con (NCT05854160)
- Testing
- Electrical Pulse Train Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Down Syndrome, Alzheimer Disease
Brain Outcomes With Lifestyle Change in Down Syndrome
The goal of this study is to determine if weight loss or changes in dietary intake can help prevent of delay adults with Down syndrome from developing Alzheimer's Disease Adults with Down syndrome without dementia will be…
- Conditions
- Down Syndrome, Alzheimer Disease, Obesity
- Trial name
- BOLD (NCT05985486)
- Testing
- Diet, Health Education
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Kansas Medical Center
Sleep Deprivation
Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study)
This randomized, double-blind, placebo-controlled trial aims to investigate whether n-3 polyunsaturated fatty acid (PUFA) supplementation attenuates abdominal visceral fat accumulation induced by experimental sleep restriction.
- Trial name
- NCT07897097
- Testing
- n-3 PUFA Supplementation, Experimental Sleep Restriction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Schizophrenia, Psychotic Disorders
Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis
The aim of the present single-blind randomized-controlled therapy study is to assess the efficacy of a new form of Cognitive Behavioral Therapy for delusions with a focus on emotion regulation, improvement of self-esteem and…
- Conditions
- Schizophrenia, Psychotic Disorders, Delusions, Emotions
- Trial name
- CBTd-E (NCT02787135)
- Testing
- emotion-oriented Cognitive Behavior Therapy
- Where
- 2 sites in Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Fibromyalgia
Effects of Diatermy in Patients With Fibromyalgia.
Diathermy is a non-invasive pain therapy based on the local application of high-frequency electromagnetic waves. This procedure produces deep heat promotes tissue repair and influences pain sensitivity.
- Trial name
- FIBDIAT (NCT06414369)
- Testing
- Diathermy, Simulated Diathermy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Camilo Jose Cela University
Psychological Distress
Lifestyle Hub Pilot Study
This study will examine the effects of a smartphone-based lifestyle medicine (LM) for improving psychological well-being in Chinese population.
- Trial name
- NCT04295369
- Testing
- Lifestyle Medicine
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Delphi Consensus Excessive Daytime Sleepiness in OSA
The objective of this study is to generate expert consensus statements on the differential diagnosis, definition, and management of EDS in patients with OSA who are adequately treated with primary therapy.
- Trial name
- NCT05055271
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College London
Covid19, Respiratory Disease
Home-based Respiratory Physiotherapy and Telephone-Based Psychological Support in Severe COVID-19 Patients
Some COVID-19 survivors may have respiratory and mental health sequelae, especially those who required hospitalization. The investigators hypothesize that the participation of a rehabilitation program composite by home-based…
- Conditions
- Covid19, Respiratory Disease, Mental Health Disorder
- Trial name
- WAYRA (NCT04649736)
- Testing
- Respiratory and psychological rehabilitation
- Where
- Peru
- Volunteers
- 108 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Health Behavior
Health Behavior Change During COVID-19 Pandemic
This study aims at investigating handwashing behavior during COVID-19 pandemic. It was hypothesized that social-cognitive and emotional predictors as well as COVID-19 morbidity and mortality rates within the country would be…
- Trial name
- NCT04367337
- Testing
- No intervention
- Where
- 14 sites in Australia, Canada and 12 more
- Volunteers
- 6,079 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Schizophrenia, Schizoaffective Disorder
Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia
This study will integrate and adapt a cognitive remediation (Cognitive Enhancement Therapy [CET]) and an affect regulation (Personal Therapy [PT]) intervention for 50 individuals with schizophrenia that misuse cannabis.
- Trial name
- NCT01292577
- Testing
- CET/PT, Treatment as Usual
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Obsessive-Compulsive Disorder, Obsessive-compulsive Disorders and Symptoms
Cognitive Bias Modification for OCD
This study will conduct the development and preliminary evaluation of Cognitive Bias Modification for Interpretation (CBM-I) and Approach Avoidance Training (AAT) as augmentations to treatment as usual for OCD and related…
- Trial name
- NCT03799419
- Testing
- Cognitive bias modification for interpretation bias, Psychoeducation, Approach avoidance training
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mclean Hospital
Social Anxiety Disorder (SAD), Oppositional Defiant Disorder
ACTsocially: The (Dis)Similarities of ACT for Changing Internalizing and Externalizing Symptomatology in Adolescence
Social functioning, fundamental to adolescent's development and mental health, may be impaired by polarizing problematic social functioning, namely externalizing symptoms manifested by Oppositional Defiant Disorder and…
- Trial name
- ACTsocially (NCT07456631)
- Testing
- ACTsocially
- Where
- Portugal
- Volunteers
- 54 people
- Sponsor
- University of Coimbra
Unintentional Burn Injury, Depression
Integrated Case Management for Burns Care in Pakistan
To test whether a culturally adapted multicomponent intervention for improving burns care and patient/family rehabilitation is effective in improving survival among burn victims in Pakistan and is cost-effective.
- Conditions
- Unintentional Burn Injury, Depression, Anxiety, Burns
- Trial name
- BURNS (NCT06559501)
- Testing
- Integrated case manager care
- Where
- 11 sites in Pakistan
- Volunteers
- 1,045 people
- Sponsor
- Pakistan Institute of Living and Learning
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