Clinical trials: Change; Mental
Obesity, Weight Gain, Maternal
Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women
Moms Are Worth It is a lifestyle behavior intervention study aims to prevent excessive gestational weight gain in overweight or obese pregnant women through promotion of the stress management, healthy eating, and physical…
- Trial name
- MAWI (NCT04623008)
- Testing
- Goal-Oriented Episodic Future Thinking
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anxiety, Depression
Internet-delivered Cognitive Behavioural Therapy in Arabic for Anxiety and Depression
The purpose of this study is to evaluate the efficacy of a culturally adapted internet-administrated cognitive behaviour therapy (ICBT) in Arabic for anxiety and depression
- Trial name
- NCT03496350
- Testing
- Internet-delivered CBT
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Linkoeping University
Attention Bias Modification Treatment (ABMT)
Attention Bias Modification Treatment (ABMT) for Patients With Post Traumatic Stress Disorder (PTSD)
Patients with Post Traumatic Stress Disorder (PTSD) will be randomly assigned to either Attention Bias Modification Treatment (ABMT) designed to normalize threat-related attention biases or a placebo control condition not…
- Trial name
- NCT01368302
- Testing
- Attention Bias Modification Treatment (ABMT)
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Tel Aviv University
Obesity, Overweight (BMI > 25)
CHANGES IN SLEEP QUALITY AND BODY COMPOSITION FOLLOWING A MULTIMODAL LIFESTYLE INTERVENTION IN OLDER WOMEN
This single-arm pilot study evaluated changes in sleep quality, body composition, biochemical parameters, physical activity, and psychological well-being following a 12-week multimodal lifestyle intervention in overweight and…
- Conditions
- Obesity, Overweight (BMI > 25), Sleep Quality, Body Composition
- Trial name
- NCT07740902
- Testing
- Multimodal Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Major Depressive Disorder, Neuroticism
Predictors of Cognitive Outcomes in Geriatric Depression
This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging.
- Conditions
- Major Depressive Disorder, Neuroticism, Cognitive Change, Stress
- Trial name
- NBOLD (NCT05273996)
- Testing
- Sertraline, bupropion, desvenlafaxine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- David Steffens
Psychosis
Culturally Adapted Cognitive Behavior Therapy for Psychosis in Pakistan
Aim: To assess the feasibility of application of culturally-adapted CBT (CaCBTp) for use in Pakistan. Design: Randomized Control Trial Setting: Psychiatry Departments of General Hospitals in Karachi.
- Trial name
- NCT02202694
- Testing
- Culturally Adapted Cognitive behavior therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Pakistan Institute of Living and Learning
Bipolar Disorder, Youth
Prospective Metabolic Monitoring of Youth and Adults With Bipolar Disorder
Background: Most psychotropic medications that are effective in the treatment of Bipolar Disorder (BD) are associated with endocrine-metabolic changes (EMCs).
- Conditions
- Bipolar Disorder, Youth, Adults
- Trial name
- NCT01282281
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Dr. Ayal Schaffer
Astrogliosis, Postoperative Cognitive Dysfunction
Association Between Changes of GFAP After Surgery and Postoperative Delayed Cognitive Recovery
Assessment of serum level of glial fibrillary acidic protein (GFAP) before surgery (on the day of surgery), 24 hours after surgery and on 3 or 4 postoperative day.
- Conditions
- Astrogliosis, Postoperative Cognitive Dysfunction, Postoperative Delirium
- Trial name
- NCT03683537
- Testing
- Glial fibrillary acidic protein
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Moscow Clinical Scientific Center
Spinal Cord Injuries, PTSD
Brief Prolonged Exposure Therapy Versus Clinical Standard to Reduce Posttraumatic Stress Post Spinal Cord Injury
This study will examine the use brief prolonged exposure (Brief PE) therapy compared to standard clinical care to reduce posttraumatic distress among people who have had a spinal cord injury and are receiving rehabilitation in an…
- Conditions
- Spinal Cord Injuries, PTSD, Post-Traumatic Stress Disorder
- Trial name
- NCT05233111
- Testing
- Brief Prolonged Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor Research Institute
Alcohol Use Disorder
Trial of a Culturally Informed Brief Intervention to Reduce Alcohol Related Health Disparities and Treatment Inequities Among Latinxs
This Stage II Randomized Efficacy Trial will compare the effectiveness of a theoretically informed and culturally responsive brief motivational intervention to a non-adapted brief intervention among non-treatment seeking Latinxs…
- Trial name
- NCT05800899
- Testing
- Brief Motivational Interviewing, Culturally adaptation brief motivational interviewing
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Texas, El Paso
Schizophrenia and Related Disorders, Immune Suppression
The Norwegian Prednisolone in Early Psychosis Study
Objective: The primary objective of this trial is to investigate whether prednisolone improves symptom severity as compared to placebo when given in addition to antipsychotic medication to patients with early-stage psychotic…
- Conditions
- Schizophrenia and Related Disorders, Immune Suppression, Psychosis, Cognitive Change
- Trial name
- NorPEPS (NCT03340909)
- Testing
- Prednisolone
- Where
- 3 sites in Norway
- Volunteers
- 12 people
- Sponsor
- Haukeland University Hospital
Alzheimer Disease
Neuroelectrical Biomarkers for Alzheimer's Disease Stages
Recent diagnostic criteria for Alzheimer's disease (AD) recognize an extended spectrum of AD stages as part of the disease, including a preclinical stage.
- Trial name
- ESTIMATE (NCT01880151)
- Testing
- EEG
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Sustained Behavior Change, Mental Well-being
The Impact of Enhanced, Demand-side Sanitation and Hygiene Promotion on Sustained Behavior Change and Health in Ethiopia
This study is a two-year evaluation investigating the impacts of an enhanced, demand-side sanitation and hygiene intervention on sustainable adoption of improved water, sanitation, and hygiene (WASH) practices and mental…
- Trial name
- NCT03075436
- Testing
- Enhanced demand-side sanitation, hygiene, Standard of care
- Where
- Ethiopia
- Volunteers
- 10,375 people, healthy volunteers welcome
- Sponsor
- Emory University
Parkinson's Disease (PD)
Observational Study Evaluating Robotic Spinal Mobilization in 16 Parkinson's Disease Participants. The Study Recorded Changes in Mobility, Sit-to-stand Performance, and Pain Scores After a 2-week Intervention With the BackHug Device.
The goal of this completed observational pilot study was to evaluate the immediate and short-term clinical effects of robotic spinal mobilization on motor and non-motor symptoms in community-dwelling adults with Parkinson's…
- Trial name
- NCT07384364
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Pacla Medical Limited
Depression, Treatment Resistant Depression
Computational Psychiatric Approach to Depression
The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression.
- Trial name
- NCT04189939
- Testing
- clinical assessments
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Dementia of Alzheimer Type, Dementia Frontotemporal
Multifactorial Approach to Dementia, Multicentric Study
The goal of this observational study is to assess the role of narcisistic personality disorder and life stressful events in conversion rate to dementia, using a three tier approach along three research lines employing subjects…
- Conditions
- Dementia of Alzheimer Type, Dementia Frontotemporal, Narcissistic Personality Disorder, Depression
- Trial name
- NCT05923307
- Where
- Argentina
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Daniel Serrani Azcurra
Hypotension, Hypoxemia
Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit
The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low…
- Conditions
- Hypotension, Hypoxemia, Altered Mental Status, Urine Output Low
- Trial name
- NCT04410757
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Loma Linda University
Diabetes Mellitus, Type 2, Insomnia
A Study Looking to Improve Sleep and Reduce Sedentary Behaviour in Those Living With Type 2 Diabetes Mellitus
The goal of this clinical feasibility trial is to learn whether the investigators can improve sleep and reduce sedentary behaviour in people living with Type 2 diabetes mellitus with sleep problems.
- Conditions
- Diabetes Mellitus, Type 2, Insomnia, Sedentary Behavior
- Trial name
- NCT06471634
- Testing
- CBTi, Control - usual care, Sedentary behaviour reduction
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Leicester
Tobacco Cessation, Tobacco Dependence
FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers
The long-term goal of FRESH Delivers is to fill a critical gap in knowledge on the role of a home-based food delivery social intervention in the elimination of tobacco-caused cancer health burdens.
- Conditions
- Tobacco Cessation, Tobacco Dependence, Food Security
- Trial name
- NCT05429892
- Testing
- Smoking cessation counseling and food delivery, Smoking cessation counseling, Food delivery
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
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