Clinical trials: Change; Mental
ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child
Triple P forADHD Children's Mothers, Education of Behavioral Problems, and Change in Mothers' Attitude
The goal of this clinical trial is to investigate whether the Triple P program will reduce behavioral problems for ADHD children, improve mothers' sense of competency, and improve their attitudes The main questions it aims to…
- Conditions
- ADHD, Predominantly Hyperactive - Impulsive, Behavior Problems, Child, ADHD - Attention Deficit Disorder With Hyperactivity, Healthy Adult Females
- Trial name
- (ADHD) (NCT07069621)
- Testing
- Triple p level parenting program
- Where
- Palestinian Territories
- Volunteers
- 67 people
- Sponsor
- Palestine Polytechnic University
Functional Abdominal Pain Syndrome, Anxiety
Neural Mechanisms of Treatment Response to ADAPT
Complex functional abdominal pain disorders (FAPD) with co-occurring anxiety are highly prevalent in children, can be very disabling, and are not responsive to currently available treatments.
- Trial name
- NCT03518216
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Michigan State University
Cirrhosis, PTSD
Microbiome Modulation With Prebiotics in PTSD and Cirrhosis
Despite medical advancements, PTSD remains a major issue in Veterans1. Current treatment strategies have relatively poor adherence.
- Trial name
- RESIST-PTSD (NCT06464952)
- Testing
- Resistant potato starch, Powdered cellulose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Post Traumatic Stress Disorder
Recording Heart Rate Variability During Eye Movement Desensitisation Reprocessing With or Without Eye Movement
The purpose of the study is to gain greater insight into Eye Movement Desensitisation Reprocessing (EMDR). EMDR is an NHS recommended treatment, which can significantly reduce trauma symptoms.
- Trial name
- EMDR;PTSD (NCT02565563)
- Testing
- Eye Movement Desensitisation Reprocessing, HeartMath measuring Heart Rate Variability (HRV)
- Sponsor
- University of Edinburgh
PTSD
ACT With Feedback for Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to explore the efficacy of Attention Control Training with the inclusion of feedback for Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT05242263
- Testing
- Attention Control Training (ACT) with ABV feedback
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Postnatal Depression
Culturally Adapted CBT Based Guided Self-Help in Patients With Postnatal Depression
This is a randomized controlled assessor-blind clinical trial comparing CaCBT based guided self-help (using a manual titled Khushi Aur Khatoon) against treatment as usual (TAU)
- Trial name
- NCT04347499
- Testing
- CaCBT based guided self help using Khushi aur Khatoon Manual
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Peshawar Medical College
Delirium
Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults
(From NIH reporter) Each year >16 million older Americans undergo anesthesia and surgery, and up to 40% of these patients develop postoperative cognitive dysfunction (POCD), a syndrome of postoperative thinking and memory…
- Trial name
- INTUIT (NCT03273335)
- Testing
- Millipore biomarker assay plate
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Duke University
Erectile Dysfunction
Bioequivalence Study Comparing Two Test Products With One Reference Product, All Containing 5 mg Yohimbine
Type: Bioequivalence study in male healthy volunteers, therapeutical indication (erectile disfunction) not studied Products, dosage, and route of administration: Test 1: Yohimbin "Spiegel"® (Desma GmbH, Germany), tablet…
- Trial name
- NCT00975325
- Testing
- Yohimbine
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Walter Ritter GmbH & Co
Autism Spectrum Disorder, Depression
Adaptation of a Behavioral Activation Treatment to Treat Depression in Autistic Adults
The present study aims to adapt and evaluate the feasibility of the BeatIt behavioral activation intervention for people with intellectual disabilities and low mood to be implemented with autistic individuals, with and without…
- Conditions
- Autism Spectrum Disorder, Depression, Depressive Symptoms
- Trial name
- NCT05030610
- Testing
- BeatIt-ASD
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Rutgers, The State University of New Jersey
Inflammation, Aging
Adaptive Stress Response: The Hot Yoga Study
This is a small intervention study which is aimed at characterizing what is known as the adaptive stress response (also know as "hormesis") in women aged 30-45 years.
- Conditions
- Inflammation, Aging, Depression, Anxiety
- Trial name
- NCT06395376
- Testing
- Bikram Hot Yoga Intervention, Hot Yoga Washout
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alzheimer's Disease, Huntington Disease
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
This study will evaluate four different modified release formulation to estimate the amount of dimebon available to the body relative to the current dimebon formulation that is given three times a day.
- Trial name
- NCT00988624
- Testing
- Dimebon IR Tablet, Dimebon MR1, Dimebon MR2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Mild Cognitive Impairment
Lithium As a Treatment to Prevent Impairment of Cognition in Elders
Alzheimer's disease (AD) is the most common cause of dementia in adults 65 years and older. AD leads to a complete loss of memory and independent function, and presently there is no cure.
- Trial name
- LATTICE (NCT03185208)
- Testing
- Lithium Carbonate
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Ariel Gildengers, MD
Mindfulness, Borderline Personality Disorder
Change in Mindfulness in Borderline Personality Disorder
The current study aims to investigate the effect of dialectical behavioral therapy on mindfulness in patients with Borderline Personality Disorder. A treatment group will be compared to a waitlist control group.
- Trial name
- NCT03297840
- Testing
- Dialectical Behavioural Therapy (DBT)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Katharina Bachmann
Preoperative Care, Anxiety
Perioperative Effects of Operating Room Virtual Tour
Preoperative anxiety is associated with adverse consequences such as emergence delirium, and postoperative behavioral changes. According to previous studies, providing information of anesthetic procedures helps to lessen…
- Conditions
- Preoperative Care, Anxiety, Emergence Delirium, Postoperative Complications
- Trial name
- NCT03172182
- Testing
- a 360-degree VR video tour
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Anxiety, Burns
Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing Changes
The primary aim of this pilot study is to establish the safety and feasibility of patient-controlled administration with dexmedetomidine for anxiolysis (PCA-DEX) during burn care dressings for patients with burn injury.
- Trial name
- NCT02409810
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Substance Use Disorders
Juvenile Justice Translational Research on Interventions for Adolescents in the Legal System
This is a multi site experiment to evaluate the impact of various strategies for increasing the use of evidence based screening, assessment and linkage to substance use treatment.
- Trial name
- (JJ-TRAILS) (NCT02672150)
- Testing
- Core, Enhanced
- Where
- 8 sites in United States
- Volunteers
- 839 people
- Sponsor
- Chestnut Health Systems
Anxiety Disorders
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase
Anxiety is chronic, debilitating, and the most common mental health problem across development, costing the U.S. over $42 billion annually.
- Trial name
- NCT07818876
- Testing
- Cognitive Bias Modification for Interpretations (CBM-I), Cognitive Restructuring (CR)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Denver
Depression, Unipolar, Depressive Disorder
Gaze Contingent Feedback in Major Depressive Disorder (MDD)
The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)
- Conditions
- Depression, Unipolar, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02945735
- Testing
- Attention Modification
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease
Terazosin Effect on Cardiac Changes in Early Parkinson's Disease
Parkinson's disease (PD) is characterized by many non-motor symptoms that occur several years before the diagnosis, in particular idiopathic REM behavior disorder (iRBD), which is associated with autonomic impairment.
- Conditions
- REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease, Symptomatic Parkinson Disease
- Trial name
- NCT04386317
- Testing
- Terazosin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cedars-Sinai Medical Center
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