Clinical trials: Chatbot, open to volunteers
Nursing Education Research, Chatbot-Based Training
A Mobile Chatbot with ARCS-V Motivation Theory on Learning Motivation
This study will implement a smartphone chatbot in medical-surgical nursing education to enhance nursing students' learning motivation and academic performance. T
- Trial name
- NCT06829628
- Testing
- chatbot teaching strategies
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Advance Care Planning
Chatbot-Assisted Advance Care Planning Education for Family Members
The goal of this clinical trial is to learn if a messaging and chatbot program, called ChatACP, helps family members of people living in nursing homes take part in advance care planning.
- Trial name
- ChatACP (NCT07448649)
- Testing
- ChatACP - Messaging- and-Chatbot Assisted Nursing Consultation, ACP self- learning handout (Hong Kong Hospital Authority ACP education material)
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cancer, Stress, Psychological
Brief Mindfulness Chatbot Intervention for Cancer Patients
This study tests a new digital tool for hospitalized cancer patients. The tool is a chatbot on LINE, a popular messaging app. The chatbot is called Mindbot. Mindbot leads a 10-minute mindfulness practice each day.
- Trial name
- MINDBOT-CA (NCT07811739)
- Testing
- Mindbot: Brief Mindfulness-Based LINE Chatbot with Virtual Reality
- Volunteers
- 66 people
- Sponsor
- Taipei Medical University
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Mild-to-Moderate Mandibular Anterior Crowding
Bracketless Orthodontic Treatment (3D-BOT) Versus Conventional Fixed Braces for Mild-to-Moderate Lower Front Tooth Crowding in Adults
This study will compare two fixed orthodontic treatments for mild-to-moderate crowding of the lower front teeth in adults. Participants will be randomly assigned to three-dimensional bracketless orthodontic treatment (3D-BOT)…
- Trial name
- 3D-BOT-RCT (NCT07897864)
- Testing
- Conventional Labial Fixed Orthodontic Appliance, 3D-BOT Using E-WIRE Archwires
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- University of Aleppo
Anxiety, Depression in Adolescence
Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India
The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and/or depression in rural…
- Conditions
- Anxiety, Depression in Adolescence, Anxiety Disorder of Adolescence
- Trial name
- NCT07595029
- Testing
- Digital psychosocial tool
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wysa
Visceral Surgery Complications
Chatbot on the Prevention of Postoperative Complications
Major visceral surgery encompasses a broad range of operations with a wide variety of procedures that fall under this category. The majority of patients undergoing major visceral surgery often present with cancer and other…
- Trial name
- NCT06624995
- Testing
- chatbot education
- Volunteers
- 214 people
- Sponsor
- Mansoura University
Breast Cancer
Design and Pilot Implementation of a Chatbot to Support Breast Cancer Screening Among Black Women
Black women are more likely than White women to be diagnosed at later stages and to die from breast cancer. Increasing breast cancer screening rates could help improve early detection of and survival from breast cancer.
- Trial name
- NCT07858825
- Testing
- Chatbot
- Volunteers
- 873 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cancer, Financial Toxicity
SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care
This is a randomized, two-arm, parallel-group pilot trial investigating a new chatbot tool designed to support cancer patients and caregivers, particularly those in rural communities.
- Trial name
- NCT07410689
- Testing
- Rule-Based Chatbot, Hybrid Chatbot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Cervical Cancer Screening, Cervical Cancer
Using Artificial Intelligence-based ChatBot to Improve Women's Participation to Cervical Cancer Screening Programme
This project looks to improve the return rate of HPV self-sampling (HPVss) as well as the management of women HPVss positive.
- Trial name
- AppDate-You (NCT05286034)
- Testing
- Decision aid tailored to women with lower educational attainment,accessible via artificial intelligence-based Chatbot platforms
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Gynecologic Cancer, Hereditary Cancer Syndrome
Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment
In this study, the investigators aim to compare a mobile health platform, known as a 'chatbot,' that leverages artificial intelligence and natural language processing to scale communication, to 'usual care' that patients would…
- Trial name
- NCT05562778
- Testing
- Chatbot
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Smoking Cessation
Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2026: Engagement-Focused GenAI-based Chatbot for Real-Time Smoking Cessation Support
The goal of this trial is to learn if chatbot-based instant messaging works to help smoking cessation in general adult smokers. It will also learn about the experience, attitude, and perception of using an LLM-based chatbot.
- Trial name
- QTW2026 (NCT07649044)
- Testing
- AWARD advice, Brief leaflet on health warning and smoking cessation, Referral card
- Where
- Hong Kong
- Volunteers
- 998 people
- Sponsor
- The University of Hong Kong
Missed Abortion, Early Pregnancy Loss
GPT-Based Digital Assistant Support During Treatment for Induced Abortion or Missed Abortion
We have developed a digital assistant based on GPT (Generative Pre-trained Transformer) technology, trained specifically to provide empathetic, medically accurate, and guideline-based responses in Hebrew, tailored to the clinical…
- Conditions
- Missed Abortion, Early Pregnancy Loss, Abortion in First Trimester, Abortion, Medical
- Trial name
- NCT07856940
- Testing
- GPT-Based Digital Assistant
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation
Efficacy of Chatbot for Irritable Bowel Syndrome (IBS) Patients
The goal of this clinical trial is to evaluate the efficacy of an automated chatbot system in improving quality of life, reducing depression and anxiety, and decreasing visceral sensitivity in patients with Irritable Bowel…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation, Irritable Bowel Syndrome - Diarrhoea, Irritable Bowel Syndrome - Mixed
- Trial name
- IrBiS (NCT06837064)
- Testing
- Chatbot supporting system
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Chronic Pain
VETERANS AFFAIRS AUGUSTA
Chronic pain is a prevalent and debilitating condition among Veterans, often accompanied by depression, anxiety, sleep disturbances, and social isolation.
- Trial name
- NCT07776600
- Testing
- My AI Companion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Companion IQ, Inc
Stress (Psychology)
Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China
The goal of this randomized controlled trial is to evaluate the effectiveness of a mindfulness-centered stress management AI chatbot in reducing perceived stress and enhancing mental health among Chinese men who have sex with men…
- Trial name
- MSM (NCT07732621)
- Testing
- Mindfulness-centered stress management AI chatbot, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Cardiovascular Diseases, Lifestyle Factors
Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
The goal of our pragmatic clinical trial is to compare how well three different strategies might do to reduce risk factors for cardiovascular disease in patients experiencing health disparities.
- Trial name
- NCT06324981
- Testing
- Generic text messages, Interactive AI chatbot text messaging, Proactive pharmacist support
- Where
- 3 sites in United States
- Volunteers
- 2,100 people
- Sponsor
- University of Colorado, Denver