Clinical trials: Chemotherapy Effects
Cancer, Chemotherapy Effect
The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy
The aim of this study is to determine the effect of mandala application on fatigue, quality of life, rumination and alexithymia in cancer patients receiving chemotherapy.
- Conditions
- Cancer, Chemotherapy Effect, Fatigue, Quality of Life
- Trial name
- ARQULA (NCT05344820)
- Testing
- Art based mandala
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Oral Mucositis (Ulcerative) Due to Radiation
Dexpanthenol Mouthwash to Treat Oral Mucositis
Oral mucositis can be a significant problem for cancer patients. It is typically associated with pain and increased risk of infection and can lead to impaired nutritional status and inadequate hydration.it can be seen in the…
- Trial name
- NCT01318889
- Testing
- Dexpanthenol
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Oral Mucositis
Low-level Laser Therapy on Inflammatory Mediators During Chemotherapy-induced Oral Mucositis
The aim of the study is to evaluate the effect of low-level laser therapy (LLLT) on the severity of oral mucositis (OM) and inflammatory mediators (pro- and anti-inflammatory cytokines, metalloproteinases and growth factors)…
- Trial name
- LLLTHSCT (NCT02050373)
- Testing
- Low-Level laser
- Volunteers
- 51 people
- Sponsor
- Universidade Federal de Goias
Breast Cancer, Metastatic Breast Cancer
Phase II Study for Solid Metastatic Tumors
1. To induce immunity-mediated tumor response outside the radiation field (abscopal effect) after chemo-radiation of a metastatic site in metastatic breast cancer patients. 2. To monitor the induction of a T cell response. 3.
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Solid Tumor
- Trial name
- NCT02474186
- Testing
- Radiation therapy, Xeloda, paclitaxel
- Volunteers
- 41 people
- Sponsor
- NYU Langone Health
Schizophrenia
Therapeutic Drug Monitoring for Individualized Clozapine Therapy
The purpose of this study is to evaluate the factors affecting the occurrence of adverse drug reactions (glucose and lipid metabolism abnormality, changes in liver function index and sleeping tendency) and clinical effects in…
- Trial name
- NCT03523741
- Testing
- Clozapine
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Breast Cancer
Walking Meditation Exercise in Breast Cancer Patients
This study is to evaluate the effects of Walking Meditation on vascular function in breast cancer patients receiving Anthracyclines chemotherapy
- Trial name
- NCT02676531
- Testing
- Exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Breast Cancer, Chemotherapy Effect
Nab-paclitaxel Compared With Docetaxel in the Neoadjuvant Chemotherapy Breast Cancer
Comparison of docetaxel and Nab-paclitaxel in neoadjuvant chemotherapy for breast cancer
- Trial name
- NCT05251766
- Testing
- Nab paclitaxel, Docetaxel
- Volunteers
- 30 people
- Sponsor
- Xuli Meng
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
COPD
Physical Activity Enhancement Using Pedometers in COPD
Physical activity is reduced in COPD affecting morbidity and mortality and the usual advice is not good enough to increase the physical activity level.
- Trial name
- NCT01739751
- Testing
- pedometers
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- University of Chile
NPC, HNSCC
A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.).
Phase II: To evaluate the safety and tolerability of IAE0972 combined with chemotherapy selected by doctors for R/M HNSCC/NPC after failure or progress of ≤2-line system therapy, and to determine the MTD of combined therapy.
- Conditions
- NPC, HNSCC, Recurrence, Metastasis
- Trial name
- NCT06719479
- Testing
- IAE0972+ Methotrexate, IAE0972+Docetaxel, IAE0972+Gemcitabine
- Volunteers
- 60 people
- Sponsor
- SUNHO（China）BioPharmaceutical CO., Ltd.
Candidiasis, HIV Infections
A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone
To evaluate the pharmacokinetics and safety of concomitant administration of methadone and fluconazole. Injection drug users constitute the second largest subset of the U.S.
- Trial name
- NCT00000788
- Testing
- Methadone hydrochloride, Fluconazole
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breast Cancer, eHealth
Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects
Chemotherapy induces side effects varying in severity, impacting patients' quality of life and necessitating unplanned hospital care. Patient-reported outcomes (PROs) could aid in early detection and management of side effects.
- Conditions
- Breast Cancer, eHealth, Symptom Monitoring, Self Management
- Trial name
- eChemoCoach (NCT06424054)
- Testing
- eChemoCoach
- Volunteers
- 746 people
- Sponsor
- Noordwest Ziekenhuisgroep
Chemotherapy Effect, Pancreas Cancer
Prospective Registry of Patients With Pancreas Adenocarcinoma Resectable and Borderline
Unlike other types of gastrointestinal tumors, there is controversial evidence of the efficacy of neoadjuvant therapy in patients with borderline and resectable adenocarcinoma (ADK) of the pancreas, the objective of this study is…
- Trial name
- PaNLoCat (NCT05514171)
- Testing
- Neoadyuvant therapy
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Mar
Thrombopenia, Cervical Cancer
Herombopag for the Prevention of Radio-chemotherapy Induced Thrombocytopenia in Cervical Cancer
Exploring and evaluating the efficacy of herombopag in preventing thrombocytopenia due to radiotherapy for cervical cancer
- Conditions
- Thrombopenia, Cervical Cancer, Radiotherapy Side Effect, Chemotherapeutic Toxicity
- Trial name
- NCT06745219
- Testing
- herombopag
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Breast Cancer, Lung Cancer
The Effect of Zhen Qi Shen Capsule Combined With Yu Yi Kang on Breast Cancer and Lung Cancer Patients With Chemotherapy
The purpose of this study is to research more reasonable and safe methods of nutritional support to improve the nutritional status of tumor patients, which guarantees the anti-tumor treatment such as chemotherapy.
- Trial name
- NCT02771756
- Testing
- zhen qishen capsule and Oral Supplement of Yuyikang, chemotherapy, nutrition education
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences
Early Gastric Cancer, Advanced Gastric Cancer
Evaluation of the Effectiveness of Managing Chemotherapy Side Effects Using ePRO and a Standardized Telenursing Program for Cancer Patients
This is a multicenter randomized controlled clinical trial designed to evaluate the clinical efficacy and cost-effectiveness of a digital health platform that integrates a symptom reporting and management software with a…
- Conditions
- Early Gastric Cancer, Advanced Gastric Cancer, Early Lung Cancer, Advanced Lung Cancer
- Trial name
- NCT07405931
- Testing
- Standardized Telenursing, Smart Cancer Care Plus
- Where
- 5 sites in South Korea
- Volunteers
- 414 people
- Sponsor
- Ulsan University Hospital
Chemotherapy-induced Peripheral Neuropathy
Effects of a Glucoside- and Rutinoside-rich Material in Chemotherapy-induced Peripheral Neuropathy and Related Symptoms
Chemotherapy-induced peripheral neuropathy (CIPN is common among cancer patients during or after chemotherapy, and the currently available drugs cannot effectively manage the symptoms.
- Trial name
- NCT04669977
- Testing
- Mulberry juice
- Where
- Taiwan
- Volunteers
- 246 people
- Sponsor
- Taipei Medical University
Gynecological Cancers, Peripheral Neuropathy Due to Chemotherapy
The Effect of Cryocompression on Peripheral Neuropathy in Patients Receiving Chemotherapy for Gynecological Cancer
Study Design: This study is designed as a prospective, randomized controlled experimental study aiming to determine the effect of cryocompression therapy, applied during chemotherapy, on peripheral neuropathy symptoms in women…
- Trial name
- CryoPN (NCT07131618)
- Testing
- cryocompression
- Volunteers
- 78 people
- Sponsor
- Mersin University
Cardiotoxicity, Systolic Dysfunction
Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy
Oncological diseases are the main cause of death in developed countries and also in Uruguay. Advances in therapeutics have made possible to aspire to cure and in other cases long-term remission with a significant increase in…
- Conditions
- Cardiotoxicity, Systolic Dysfunction, Exercise, Aerobic
- Trial name
- AEROHEMONCO (NCT04476576)
- Testing
- Aerobic exercise (experimental), Flexibility exercise (active comparator)
- Where
- Uruguay
- Volunteers
- 38 people
- Sponsor
- Lucía Florio
Breast Cancer, Cardiac Toxicity
Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab
RATIONALE: Lisinopril or Coreg CR®, may help reduce side effects caused by trastuzumab. It is not yet known whether lisinopril or Coreg CR® are more effective than a placebo in reducing side effects caused by trastuzumab.
- Trial name
- NCT01009918
- Testing
- Coreg CR®, lisinopril
- Where
- 174 sites in United States
- Volunteers
- 468 people
- Sponsor
- University of South Florida
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