Clinical trials: Chemotherapy Induced Alopecia
Chemotherapy-induced Alopecia
Study To Evaluate The Efficacy And Safety Profile of ECOHAIR in Chemo-induced Alopecia.
This is a Phase 2, single-center study designed to determine the effect of ECOHAIR topical solution on scalp hair growth evaluated objectively ( images) and subjectively ( patient and investigator reports).
- Trial name
- NCT06020586
- Testing
- hair lotion
- Where
- Argentina
- Volunteers
- 22 people
- Sponsor
- Instituto de Oncología Ángel H. Roffo
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Pharmacokinetic Study of DA-020
Pharmacokinetic Study of DA-020
- Trial name
- NCT07402330
- Testing
- DA-020 (0.1%), DA-020 (0.2%), DA-020 (0.5%)
- Where
- 2 sites in Brazil, Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Biology, Inc.
Alopecia, Chemotherapy Effects
A 6-month Post-interventional Follow-up Extension of VOLUME Study (VOLUME-2)
We would suggest to conduct "VOLUME-2" study, as an extension of the ongoing "VOLUME" study with all subjects already included. After completion of VOLUME study, the study will be directly extend with an "open-label design".
- Trial name
- VOLUME2 (NCT02986412)
- Testing
- CG428
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Chemotherapy Adjuvant, Breast Cancer
Efficacy and Safety of Dignicap System for Preventing Chemotherapy Induced Alopecia
The efficacy and safety of the Dignicap System to prevent chemotherapy induced alopecia will be evaluated in women with early breast cancer undergoing adjuvant or neoadjuvant chemotherapy regimens.
- Trial name
- NCT01831024
- Testing
- Dignicap System
- Where
- 4 sites in United States
- Volunteers
- 110 people
- Sponsor
- Target Health Inc.
Breast Cancer, Breast - Female
CARE (Chemotherapy Alopecia REduction)
The goal of this research study is to determine if the DigniCap Scalp Cooling System can help prevent chemotherapy-induced hair loss in Black patients.
- Conditions
- Breast Cancer, Breast - Female, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- CARE (NCT07201389)
- Testing
- Scalp Cooling by DigniCap
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- George Washington University
Prevention of Chemotherapy-induced Myelosuppression
A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer
This is a Phase 1b open-label, single arm, multicenter, study of ALRN-6924 as a chemoprotection agent in patients with TP53-mutated HER2- breast cancer (stages IIa to IIIb) receiving neoadjuvant or adjuvant chemotherapy with…
- Trial name
- NCT05622058
- Testing
- ALRN-6924, TAC (doxorubicin 50 mg/m2; cyclophosphamide 500 mg/m2; docetaxel 75 mg/m2)
- Where
- 14 sites in United States, Bosnia and Herzegovina and 2 more
- Volunteers
- 6 people
- Sponsor
- Aileron Therapeutics, Inc.
Neoplasms, Alopecia
START: Swiss Taxotere Alopecia Prevention Trial
Primary objective: Rate of complete chemotherapy induced alopecia (WHO grade III or IV, physician grading) Secondary objective: Compliance to scalp cooling procedure Received number of cycles of chemotherapy in each subgroup…
- Trial name
- NCT01008774
- Testing
- Paxman Cooling Machine, Cold Caps
- Where
- Switzerland
- Volunteers
- 239 people
- Sponsor
- Sanofi
Breast Cancer, Hair Loss
Alleviation of Alopecia in Breast Cancer Patient Using Synbiotics Formula
This study aims to explore the efficacy and safety of a synbiotic formula (BLHK03) in alleviating chemotherapy-induced alopecia (CIA) in breast cancer patients and the compositional and functional changes in the gut microbiome of…
- Trial name
- NCT06560385
- Testing
- BLHK03
- Where
- 2 sites in Hong Kong
- Volunteers
- 7 people
- Sponsor
- GenieBiome Limited
Metastatic Breast Cancer, Chemotherapy-induced Alopecia
Scalp Cooling in MBC
This research is being done to compare rates of hair loss of people with metastatic breast who use scalp cooling versus those who do not use scalp cooling after receiving standard of care treatment with either sacituzumab…
- Trial name
- NCT04986579
- Testing
- Paxman Scalp Cooling System, Eribulin, Sacituzumab govitecan
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Dana-Farber Cancer Institute
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Portable Scalp Cooling System for the Improvement of Chemotherapy-Induced Hair Loss in Patients With Metastatic Breast Cancer
This clinical trial evaluates the benefits of a portable scalp cooling system (PSCS) for improving chemotherapy-induced hair loss in patients with breast cancer that has spread to other places in the body (metastatic) and are…
- Trial name
- NCT05533320
- Testing
- Cold Cap Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Sponsor
- City of Hope Medical Center
Breast Cancer, Breast Cancer Stage I
Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients
This study is being done to determine if using the Paxman Scalp Cooling System at temperatures lower than the current standard is a safe and tolerable approach to prevent hair loss in breast cancer patients receiving chemotherapy.
- Conditions
- Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III
- Trial name
- NCT04180579
- Testing
- PAXMAN Scalp Cooler
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chemotherapy-induced Alopecia
"Impact of Chemotherapy-induced Alopecia on the Quality of Life of Women With Breast Cancer"
The main objective of this qualitative phenomenological study is to understand the impact of chemotherapy-induced alopecia, the quality of life of women with breast cancer from this experience.
- Trial name
- NCT02797223
- Testing
- Semi-structured interviews
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chemotherapy-Induced Alopecia
Compound 31543 (Calcitriol, USP) in Patients Receiving Taxane-based Chemotherapy Regimens for the Treatment of Chemotherapy-Induced Alopecia
The goal of this clinical trial is to learn if Compound 31543 (topical calcitriol) for treatment of hair-loss in patients with a diagnosis of breast cancer, gynecologic cancer or sarcomas receiving a taxane-based chemotherapy is…
- Trial name
- NCT01588522
- Testing
- Compound 31543 Calcitriol 5 μg/mL, Compound 31543 Calcitriol 10 μg/mL, Compound 31543 Calcitriol 20 μg/mL
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- BPGbio
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Clinical Study of DA-007 for the Treatment of Chemotherapy Induced Alopecia
Clinical Study of DA-007 As a Treatment for Chemotherapy Induced Alopecia
- Trial name
- NCT06762548
- Testing
- DA-007
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Applied Biology, Inc.
Breast Cancer, Chemotherapy-Induced Alopecia
Effects of a Web-Based Alopecia Education Program in Women With Breast Cancer
This randomized controlled trial evaluated the effects of a web-based alopecia education program on body image, self-esteem, chemotherapy-induced alopecia-related quality of life, and psychological well-being among women with…
- Trial name
- NCT07724314
- Testing
- Web-Based Alopecia Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Gulay Akman
Chemotherapy Induced Alopecia
The Lily Device Trial
The goal of this clinical trial is to test if the Lily Device works to reduce chemotherapy induced hair loss in patients. It will also learn about the safety of the Lily Device.
- Trial name
- PREVAIL (NCT06786078)
- Testing
- Lily Device
- Where
- 5 sites in United States
- Volunteers
- 85 people
- Sponsor
- Luminate Medical, Inc.
Alopecia, Chemotherapy-Induced Change
Keratinocyte Growth Factor- Hair Serum for the Prevention of Chemotherapy Induced Alopecia
Primary aim is to provide a preliminary assessment of the efficacy of the investigational topical formula, KGF-HS, as a prophylactic treatment for chemotherapy induced alopecia.
- Conditions
- Alopecia, Chemotherapy-Induced Change, Hair Loss, Alopecia Drugs
- Trial name
- NCT04554732
- Testing
- Keratinocyte growth factor
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Arizona
Breast Cancer, Ovarian Cancer
Efficacy of Paxman Scalp Cooling to Prevent Chemo Induced Alopecia in Black Patients With Breast or GYN Cancers
This study will measure the efficacy of scalp cooling with the Paxman Scalp Cooling (PSC) device in a diverse patient population with success measured as prevention of more than 50% hair loss during chemotherapy.
- Conditions
- Breast Cancer, Ovarian Cancer, Gynecologic Neoplasm, Endometrial Cancer
- Trial name
- NCT04626895
- Testing
- Paxman Scalp Cooling Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Non-Metastatic Breast Cancer
Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer
The purpose of this study is to see how many patients develop hair, skin and nail changes due to cancer treatments. The investigators would like to study the clinical factors, genetic markers, and impact on patients'…
- Trial name
- NCT02530177
- Testing
- Clinical Assessments, Questionnaires, Saliva sample
- Where
- United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alopecia, Chemotherapy-induced Alopecia
A Pilot Study to Evaluate the Use of the AMMA Portable Scalp Cooling System From Cooler Heads
Eligible patients will be recruited prior to initiation of chemotherapy for any stage breast or gynecologic cancer. Patients will undergo training in the use of the AMMA Portable Scalp Cooling System and will use the device…
- Conditions
- Alopecia, Chemotherapy-induced Alopecia, Hair Loss, Breast Cancer
- Trial name
- NCT05365243
- Testing
- AMMA Portalbe Scalp Cooling System
- Where
- United States
- Sponsor
- Cooler Heads Care Inc.