Clinical trials: Chemotherapy Symptoms
Squamous Neck Carcinoma of the Head and Neck Cancer (SCCHN)
Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
PURPOSE: Randomized phase 2 trial to compare the effectiveness of chemo-radiation therapy (RT + cisplatin + 5-FU) with or without tirapazamine for the treatment of patients with stage III or IV squamous cell carcinomas of the…
- Trial name
- NCT00002774
- Testing
- Tirapazamine, Cisplatin, 5-fluorouracil
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Stanford University
Chemotherapy Effect
Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy
ABSTRACT Background: Today, a wide range of pediatric cancers is treated by chemotherapy. More than 21 side effects of chemotherapy have been identified. Among those nausea; vomiting, infection and anemia are most common.
- Trial name
- NCT03753542
- Testing
- Multimedia education, booklet Providence and tele-nursing follow-up
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nomi Waqas Gul
Bladder Cancer, Bladder Neoplasm
Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumors.
This study will determine whether Synergo® RITE + MMC treatment is efficacious as second-line therapy for CIS NMIBC BCG-unresponsive patients with or without papillary NMIBC, through examination of the complete response rate…
- Conditions
- Bladder Cancer, Bladder Neoplasm, Bladder Tumors, Cancer of Bladder
- Trial name
- RITE-USA (NCT03335059)
- Testing
- Synergo® RITE + MMC
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Medical Enterprises Ltd.
Mediastinal Cancer, Metastatic Cancer
Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Conditions
- Mediastinal Cancer, Metastatic Cancer, Testicular Germ Cell Tumor
- Trial name
- NCT00003941
- Testing
- bleomycin sulfate, filgrastim, cisplatin
- Where
- 37 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Chemotherapy-induced Nausea and Vomiting
Auricular Acupressure for Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy
Chemotherapy-induced nausea and vomiting (CINV) remains one of the most common and distressing adverse effects in patients receiving highly emetogenic chemotherapy (HEC).
- Trial name
- AACINV (NCT07760766)
- Testing
- Auricular Acupressure
- Where
- China
- Volunteers
- 332 people
- Sponsor
- China Medical University, China
Breast Neoplasms, Neoplasm Metastasis
Study of Chemotherapy With Adoptive Cellular Therapy With DC-CIK Cells in Triple Negative Breast Cancer Patients
To access the effectiveness of cyclophosphamide combined thiotepa and carboplatin chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells in triple negative metastatic breast cancer…
- Trial name
- DCCIK (NCT01395056)
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Peking University Cancer Hospital & Institute
Schizophrenia, Cerebellar Ataxia
A TAK-831-1001, Single and Multiple Rising Dose Study in Healthy Participants
The purpose of this study is to determine the safety, tolerability and pharmacokinetics (PK) of single and multiple rising doses of TAK-831 in healthy participants.
- Trial name
- NCT02566759
- Testing
- TAK-831 Oral Suspension, TAK-831 Tablet
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Neurocrine Biosciences
Ureteral Calculi
Medical Expulsive Therapy of Single Distal Ureteral Stones
Current therapeutic options for ureteral stones include active intervention as well as conservative "watch and wait" approaches.
- Trial name
- NCT00831701
- Testing
- Tamsulosin
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Breast Cancer
Study of the Response to a Neoadjuvant Chemotherapy Based on the Antitumor Immune Response in Localized Breast Cancer
This is a prospective, non-randomized study which aims to evaluate the response to a neoadjuvant chemotherapy according to the the antitumor immune response in localized breast cancer. 40 patients will be enrolled in the study.
- Trial name
- BREAST IMMUN (NCT01440413)
- Testing
- Blood and tumor sample
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Leon Berard
Emergency Department, Clinical Pharmacist
Integrating the Clinical Pharmacists Into Emergency Department Teams
The "Emergency Department (ED) Pharmacist" is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations.
- Trial name
- ED-PHARM (NCT04722588)
- Testing
- Introducing clinical pharmacists to the interdisciplinary ED team.
- Where
- 3 sites in Norway
- Volunteers
- 30,888 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
Hepatitis C Virus Infection
Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed Dose Combination in the Treatment of Hepatitis C Virus (HCV) Infection in Pediatric Participants Undergoing Cancer Chemotherapy
The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) in treating hepatitis C virus (HCV) infection in pediatric participants who are undergoing cancer…
- Trial name
- NCT02868242
- Testing
- LDV/SOF
- Where
- Egypt
- Volunteers
- 19 people
- Sponsor
- Gilead Sciences
Endometriosis
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
The aim of this study is to investigate whether whole-body cryotherapy (a brief exposure to very cold temperatures) can help reduce pain and improve quality of life in people living with endometriosis, and whether it may…
- Trial name
- CHILL-Endo (NCT07603960)
- Testing
- Whole-Body Cryotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Leukemia, Myelodysplastic Syndromes
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy…
- Trial name
- NCT00027924
- Testing
- busulfan, cyclosporine, fludarabine phosphate
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Non-Cancer Pain
Preventive Interventions for Chronic Pain Worsening
This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK).
- Trial name
- NCT06351046
- Testing
- Virtual Reality-based Pain Self-management program
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Mild to Moderate Depression.
Cost-effectiveness of a Non-Pharmacological Treatment (Active Monitoring) vs. a Pharmacological Treatment for Major Depression in Primary Care.
Major Depression (MD) is highly prevalent and has associated a high burden and economic costs. Mild levels of MD could be treated without antidepressants at Primary Care (PC).
- Trial name
- NCT02245373
- Testing
- Antidepressants, Active Monitoring
- Volunteers
- 263 people
- Sponsor
- Fundació Sant Joan de Déu
Ovarian Cancer
A Phase 3 Study of Manganese-primed Immunochemotherapy in Patients With Advanced Ovarian Cancer
Epithelial ovarian cancer is the most lethal gynecologic malignancy, and most patients eventually relapse and develop resistance to available therapies.
- Trial name
- NCT07822646
- Testing
- Manganese Chloride, Nab-paclitaxel, Platinum chemotherapy
- Where
- 6 sites in China
- Volunteers
- 120 people
- Sponsor
- Chinese PLA General Hospital
Tinnitus, Subjective
Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus
Therapy of subjective chronic primary tinnitus could be challenging. Repetitive transcranial magnetic stimulation (rTMS) is currently being tested for suppressing the symptoms.
- Trial name
- NCT03425045
- Testing
- Repetitive Transcranial Magnetic Stimulation, Ginkgo Biloba Extract
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Ostrava
Cancer, Chemotherapy
The Effect of Music on Pain and Anxiety in Patients Receiving Chemotherapy During COVID-19
Introduction: This study has been conducted to determine the effect of music on pain and anxiety levels in patients receiving chemotherapy during COVID-19.
- Trial name
- NCT05334641
- Testing
- Listening Music, Not Listening Music
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Inonu University
Migraine
Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of Migraine
The purpose of this study is to determine the effectiveness of melatonin 3 mg compared to placebo and amitriptyline 25 mg in the preventive treatment of migraine.
- Trial name
- EDUMAP (NCT01357031)
- Testing
- Amitriptyline, Melatonin
- Where
- Brazil
- Volunteers
- 192 people
- Sponsor
- Hospital Israelita Albert Einstein
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